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Identifier: 11498040

GI number: 11498040

Start: 385261

End: 386247

Strand: Reverse

Name: Not Available

Synonym: AF0428

Alternate gene names: 11498040

Gene position: 386247-385261 (Counterclockwise)

Preceding gene: 11498041

Following gene: 11498034

Centisome position: 17.73

GC content: 49.44

Gene sequence:

>987_bases
ATGCAGGACTTCAAGAAGCTGCCGACTGTGCTAACGGCAGAGGAGCTGATAGACAAGATTTTCAGGAGAGCTGCGAGAGT
TGAGGGGAGAAATCCAAAGGAGAAAGCCTTGAACAAGCTTGCAACAATCTCCAACGTTTCAAGGGACTACTTCGGCAAGA
TTATCGGAGCCCATCCGAGCTACGAAAACCTTCCCGACTTTTACAGGGAAATGGTTGACGTGGTTGTGGGAATAAGGCAG
CTCAAGAAGTCCCTCGTAGCGCTGAAGTGGGCGGACGGGATGATTCAGAAGGTTGTGAGCAGAGCTGTGAGGGAAGTTAA
GGGCGGTAAAAATCCCTCTGCTGTGGTTAAATCTGCCTACGGCAGAGTTGCATCAATCATCGAGCAGATTGATGATGAGC
TTAGGTTCCTGAACGATGCCAAAAACAGGATGAGGGAGATACCCATTCTTCAGGATTTGCCCACAATCGTCGTTGCAGGC
TACCCCAATGTAGGAAAATCTTCGCTCGTTGCAAGAATCTCAACGGTAAAGCCAGAGGTTGCCAGCTACCCCTTCACCAC
CAAGAAAATCAACCTCGGCTTTGCTGAATTTGCTGGAAAGAGAGTCCAAATCATTGACACGCCCGGTCTTCTTGACAGGC
CGTTGAGCAAGAGAAACAGAATTGAGAGGAGGGCGGTTCTCGCTTTAAAGCACCTCGCTGACATAATCCTTTTCGTCATT
GACCCAACAGAAACCTGCGGATACTCTCTGGAAAAGCAGCTTTCCCTTCTCGAGGAGATAAAGGGCTACTTCGCCAAGCC
AACAGTAGAGGTGTACAGCAAGGCTGACATGCACGACAGAAGGGATAGACAAGCTTACTCAGCCGTTACAGGCGAGGGAA
TTGACGAGCTAATCAAAGAAATAGAAAAAATGGTAAAAATTCACTCGCAGACGTCTACGGTGATTGCCCCCTCAGGGCAG
ACCTCAACGCAGGAGCAGCACTCCTGA

Upstream 100 bases:

>100_bases
GAAAAACATGACTTTGAGATTCTCGGCATCCACAGCTATGGGGACCAAAAAATGATAGTGGCAAGGAAAACAAAATAAGC
CCTGAGCAAAACTTCAGCAG

Downstream 100 bases:

>100_bases
CACTCGTCCGGGTTTGCCGGGTAGCTCTTCCCGTCGTCGTTGAACTCAAACACTCCTCCGGGGCAAACGGAAATGCACTC
TCCACATCCGCTGCACTTGT

Product: GTP1/OBGfamily GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MQDFKKLPTVLTAEELIDKIFRRAARVEGRNPKEKALNKLATISNVSRDYFGKIIGAHPSYENLPDFYREMVDVVVGIRQ
LKKSLVALKWADGMIQKVVSRAVREVKGGKNPSAVVKSAYGRVASIIEQIDDELRFLNDAKNRMREIPILQDLPTIVVAG
YPNVGKSSLVARISTVKPEVASYPFTTKKINLGFAEFAGKRVQIIDTPGLLDRPLSKRNRIERRAVLALKHLADIILFVI
DPTETCGYSLEKQLSLLEEIKGYFAKPTVEVYSKADMHDRRDRQAYSAVTGEGIDELIKEIEKMVKIHSQTSTVIAPSGQ
TSTQEQHS

Sequences:

>Translated_328_residues
MQDFKKLPTVLTAEELIDKIFRRAARVEGRNPKEKALNKLATISNVSRDYFGKIIGAHPSYENLPDFYREMVDVVVGIRQ
LKKSLVALKWADGMIQKVVSRAVREVKGGKNPSAVVKSAYGRVASIIEQIDDELRFLNDAKNRMREIPILQDLPTIVVAG
YPNVGKSSLVARISTVKPEVASYPFTTKKINLGFAEFAGKRVQIIDTPGLLDRPLSKRNRIERRAVLALKHLADIILFVI
DPTETCGYSLEKQLSLLEEIKGYFAKPTVEVYSKADMHDRRDRQAYSAVTGEGIDELIKEIEKMVKIHSQTSTVIAPSGQ
TSTQEQHS
>Mature_328_residues
MQDFKKLPTVLTAEELIDKIFRRAARVEGRNPKEKALNKLATISNVSRDYFGKIIGAHPSYENLPDFYREMVDVVVGIRQ
LKKSLVALKWADGMIQKVVSRAVREVKGGKNPSAVVKSAYGRVASIIEQIDDELRFLNDAKNRMREIPILQDLPTIVVAG
YPNVGKSSLVARISTVKPEVASYPFTTKKINLGFAEFAGKRVQIIDTPGLLDRPLSKRNRIERRAVLALKHLADIILFVI
DPTETCGYSLEKQLSLLEEIKGYFAKPTVEVYSKADMHDRRDRQAYSAVTGEGIDELIKEIEKMVKIHSQTSTVIAPSGQ
TSTQEQHS

Specific function: Gtpase Of Unknown Physiological Role. [C]

COG id: COG1084

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP1/OBG family. NOG subfamily [H]

Homologues:

Organism=Homo sapiens, GI55953087, Length=311, Percent_Identity=27.3311897106109, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI24308117, Length=171, Percent_Identity=29.2397660818713, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145602, Length=315, Percent_Identity=30.1587301587302, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25145600, Length=315, Percent_Identity=30.1587301587302, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6325164, Length=284, Percent_Identity=29.9295774647887, Blast_Score=146, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6321612, Length=101, Percent_Identity=41.5841584158416, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19921908, Length=296, Percent_Identity=31.7567567567568, Blast_Score=147, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006073
- InterPro:   IPR010674
- InterPro:   IPR005225 [H]

Pfam domain/function: PF06858 NOG1 [H]

EC number: NA

Molecular weight: Translated: 36764; Mature: 36764

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDFKKLPTVLTAEELIDKIFRRAARVEGRNPKEKALNKLATISNVSRDYFGKIIGAHPS
CCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YENLPDFYREMVDVVVGIRQLKKSLVALKWADGMIQKVVSRAVREVKGGKNPSAVVKSAY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GRVASIIEQIDDELRFLNDAKNRMREIPILQDLPTIVVAGYPNVGKSSLVARISTVKPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEECCCCCCHHHHHHHHHHCCCHH
ASYPFTTKKINLGFAEFAGKRVQIIDTPGLLDRPLSKRNRIERRAVLALKHLADIILFVI
HCCCCCCCEECCCHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
DPTETCGYSLEKQLSLLEEIKGYFAKPTVEVYSKADMHDRRDRQAYSAVTGEGIDELIKE
CCCHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHH
IEKMVKIHSQTSTVIAPSGQTSTQEQHS
HHHHHHHHHCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure
MQDFKKLPTVLTAEELIDKIFRRAARVEGRNPKEKALNKLATISNVSRDYFGKIIGAHPS
CCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YENLPDFYREMVDVVVGIRQLKKSLVALKWADGMIQKVVSRAVREVKGGKNPSAVVKSAY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GRVASIIEQIDDELRFLNDAKNRMREIPILQDLPTIVVAGYPNVGKSSLVARISTVKPEV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCEEEECCCCCCHHHHHHHHHHCCCHH
ASYPFTTKKINLGFAEFAGKRVQIIDTPGLLDRPLSKRNRIERRAVLALKHLADIILFVI
HCCCCCCCEECCCHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEE
DPTETCGYSLEKQLSLLEEIKGYFAKPTVEVYSKADMHDRRDRQAYSAVTGEGIDELIKE
CCCHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHH
IEKMVKIHSQTSTVIAPSGQTSTQEQHS
HHHHHHHHHCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]