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The map label for this gene is purP

Identifier: 11497872

GI number: 11497872

Start: 232716

End: 233837

Strand: Reverse

Name: purP

Synonym: AF0256

Alternate gene names: 11497872

Gene position: 233837-232716 (Counterclockwise)

Preceding gene: 11497873

Following gene: 11497870

Centisome position: 10.73

GC content: 48.48

Gene sequence:

>1122_bases
ATGAATCCGCGGAAAATCGCAGCCAGTTACGAGGACGTCACCATAGGAATTTTCGGCTCTCACTCAGCGAAGGAAGTGGG
AATGGCTGCAAAAGCCTGGGGCTTCAAGACAGTCATCGTCGTGCAGAGGGGAAGGGACAAGCTTTACACCAAATACAACA
GGCACCTTTATGATGAGGTGATAATGGTCGAGAAGTTTAAGGACATACTTAACAGGGAAATTCAGGAAAAACTACTCGAA
TTGAACACCATTTTCATCCCCAACAGGAGCTTTGCCGTGTATGTCGGTTACGACGGTATAGAGAAGGAGTTTGAAGTCCC
GATTTACGGCAACAGGTTTATGCTGAGAGCTGAGGAGAGAAACCACCCTAAAAACCAGTACTACCTTCTCGAAAAGGCAG
GTTTGAGGTATCCCAAGGAGTTCAAGTCTCCGGAGGAGATCGACAGGCTCGTGATAGTCAAGGTTCAGCAGGCGAAGAAT
CCACTCGAAAGAGCCTTTTTCTACGCCGTTTCGCCGGAAGACTACTACGAGCAGGCTGAGAGATTGCTGAAGGAAGGTGT
AATTGACGAGGAGGGGCTAAAAAAGGCCAGAATAGAGGAGTACGTGTTGGGAGCGAGGTTCAACGCCAACTTCCACAGTT
ACGCCCTTAAAGACGTGTTTGGGAACTTTGACTTTGTGGGGTTCAGCGACAGGAGACAGGTCAACCTGCAGGGATTTCTG
AACCTGCCTGCGAAGGATCAGCTAAAGATTAACGTTCCGGTAAAGAACGAGGAGATTGGTCATTTCGGAGTTACCATGAG
GGAGAGCAAGCAGCAAGAAGTTTACGAGGCTGCAGAGAAGTTCATCGAAGCCTGCAAAGCTGAATTTCCACCGGGAATCA
TAGGCATGTTCGGTCTGCAGGGAGCAATGGCTTACTCTCCCGAGGATGAGACGAAGCTTGAGTTCGTAATCTTCGATGTC
TCCTTCAGGGTTCCTGGCGACCCTGCAATAGGCCCCACATCGCCGGAGATGAGAAACCTCACACTTAAGCATGGTGTGAA
GATAGAAGACCCACTGGATTTGACAATGATGGAAATAAAAAAGGCGATGGAGCTCAAAAGAATGGAAGAGATAGTTACTT
AA

Upstream 100 bases:

>100_bases
GTTTATTGCGGTGTTCGTGTTGAGAATTTTGTAAAAGTCCGAAACTTTCGCACTGCAATACATTACCAATCAATTTTTTA
AGTGCGACACAACGTGAAAC

Downstream 100 bases:

>100_bases
CCGGCCTCAAGCAGCTCAATCCCGTCGTCAGTAAGCTTCAGCTTCCCATCTTCCTCTTTTACAAACCCCTCTCTTATGAG
CCAGTCCAGATTGAACTTGA

Product: 5-formaminoimidazole-4-carboxamide-1-(beta)-D- ribofuranosyl 5'-monophosphate synthetase-like protein

Products: NA

Alternate protein names: 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNPRKIAASYEDVTIGIFGSHSAKEVGMAAKAWGFKTVIVVQRGRDKLYTKYNRHLYDEVIMVEKFKDILNREIQEKLLE
LNTIFIPNRSFAVYVGYDGIEKEFEVPIYGNRFMLRAEERNHPKNQYYLLEKAGLRYPKEFKSPEEIDRLVIVKVQQAKN
PLERAFFYAVSPEDYYEQAERLLKEGVIDEEGLKKARIEEYVLGARFNANFHSYALKDVFGNFDFVGFSDRRQVNLQGFL
NLPAKDQLKINVPVKNEEIGHFGVTMRESKQQEVYEAAEKFIEACKAEFPPGIIGMFGLQGAMAYSPEDETKLEFVIFDV
SFRVPGDPAIGPTSPEMRNLTLKHGVKIEDPLDLTMMEIKKAMELKRMEEIVT

Sequences:

>Translated_373_residues
MNPRKIAASYEDVTIGIFGSHSAKEVGMAAKAWGFKTVIVVQRGRDKLYTKYNRHLYDEVIMVEKFKDILNREIQEKLLE
LNTIFIPNRSFAVYVGYDGIEKEFEVPIYGNRFMLRAEERNHPKNQYYLLEKAGLRYPKEFKSPEEIDRLVIVKVQQAKN
PLERAFFYAVSPEDYYEQAERLLKEGVIDEEGLKKARIEEYVLGARFNANFHSYALKDVFGNFDFVGFSDRRQVNLQGFL
NLPAKDQLKINVPVKNEEIGHFGVTMRESKQQEVYEAAEKFIEACKAEFPPGIIGMFGLQGAMAYSPEDETKLEFVIFDV
SFRVPGDPAIGPTSPEMRNLTLKHGVKIEDPLDLTMMEIKKAMELKRMEEIVT
>Mature_373_residues
MNPRKIAASYEDVTIGIFGSHSAKEVGMAAKAWGFKTVIVVQRGRDKLYTKYNRHLYDEVIMVEKFKDILNREIQEKLLE
LNTIFIPNRSFAVYVGYDGIEKEFEVPIYGNRFMLRAEERNHPKNQYYLLEKAGLRYPKEFKSPEEIDRLVIVKVQQAKN
PLERAFFYAVSPEDYYEQAERLLKEGVIDEEGLKKARIEEYVLGARFNANFHSYALKDVFGNFDFVGFSDRRQVNLQGFL
NLPAKDQLKINVPVKNEEIGHFGVTMRESKQQEVYEAAEKFIEACKAEFPPGIIGMFGLQGAMAYSPEDETKLEFVIFDV
SFRVPGDPAIGPTSPEMRNLTLKHGVKIEDPLDLTMMEIKKAMELKRMEEIVT

Specific function: Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates [H]

COG id: COG1759

COG function: function code R; ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013816
- InterPro:   IPR009720
- InterPro:   IPR010672
- InterPro:   IPR013817 [H]

Pfam domain/function: PF06849 DUF1246; PF06973 DUF1297 [H]

EC number: NA

Molecular weight: Translated: 43044; Mature: 43044

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRKIAASYEDVTIGIFGSHSAKEVGMAAKAWGFKTVIVVQRGRDKLYTKYNRHLYDEV
CCCHHEECCCCEEEEEEECCCCHHHHCCCHHHCCCEEEEEEECCCHHHHHHHHHHHHHHH
IMVEKFKDILNREIQEKLLELNTIFIPNRSFAVYVGYDGIEKEFEVPIYGNRFMLRAEER
HHHHHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCEECEEECCEEEEEECCC
NHPKNQYYLLEKAGLRYPKEFKSPEEIDRLVIVKVQQAKNPLERAFFYAVSPEDYYEQAE
CCCCCCEEEEECCCCCCCHHCCCHHHHCEEEEEEEHHHCCHHHHHEEEEECCHHHHHHHH
RLLKEGVIDEEGLKKARIEEYVLGARFNANFHSYALKDVFGNFDFVGFSDRRQVNLQGFL
HHHHCCCCCHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHCCCCEEECCCCCEEEEEEEE
NLPAKDQLKINVPVKNEEIGHFGVTMRESKQQEVYEAAEKFIEACKAEFPPGIIGMFGLQ
CCCCCCCEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHCCC
GAMAYSPEDETKLEFVIFDVSFRVPGDPAIGPTSPEMRNLTLKHGVKIEDPLDLTMMEIK
CCEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHCCHHHCCCEECCCCCHHHHHHH
KAMELKRMEEIVT
HHHHHHHHHHHCC
>Mature Secondary Structure
MNPRKIAASYEDVTIGIFGSHSAKEVGMAAKAWGFKTVIVVQRGRDKLYTKYNRHLYDEV
CCCHHEECCCCEEEEEEECCCCHHHHCCCHHHCCCEEEEEEECCCHHHHHHHHHHHHHHH
IMVEKFKDILNREIQEKLLELNTIFIPNRSFAVYVGYDGIEKEFEVPIYGNRFMLRAEER
HHHHHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCEECEEECCEEEEEECCC
NHPKNQYYLLEKAGLRYPKEFKSPEEIDRLVIVKVQQAKNPLERAFFYAVSPEDYYEQAE
CCCCCCEEEEECCCCCCCHHCCCHHHHCEEEEEEEHHHCCHHHHHEEEEECCHHHHHHHH
RLLKEGVIDEEGLKKARIEEYVLGARFNANFHSYALKDVFGNFDFVGFSDRRQVNLQGFL
HHHHCCCCCHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHCCCCEEECCCCCEEEEEEEE
NLPAKDQLKINVPVKNEEIGHFGVTMRESKQQEVYEAAEKFIEACKAEFPPGIIGMFGLQ
CCCCCCCEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHCCC
GAMAYSPEDETKLEFVIFDVSFRVPGDPAIGPTSPEMRNLTLKHGVKIEDPLDLTMMEIK
CCEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHCCHHHCCCEECCCCCHHHHHHH
KAMELKRMEEIVT
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]