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Identifier: 15679703

GI number: 15679703

Start: 1566136

End: 1566657

Strand: Direct

Name: Not Available

Synonym: MTH1709

Alternate gene names: 15679703

Gene position: 1566136-1566657 (Clockwise)

Preceding gene: 15679702

Following gene: 15679704

Centisome position: 89.42

GC content: 48.85

Gene sequence:

>522_bases
GTGATAGTCTTGAATGACAGAATAATACCATGGCAGCCCACTGTTATAGCCGGGCCAAAACAGGCAATGCTCGTAACACC
CGAAACTGCGACCATGATGATAAAAAAGGCCAGGAGGCCACTTATGGTTGTAGGGCCACTCGCCAAGCGCCAGGAAGTGC
TTGAACATACGGTTAAAATCATAAGGCACTTCGATTTACCGGTGGTAGCAACGGCAGACACCTACAGGGCACTGAGTGAG
GCCGGCATAGAATCAGAGCCCCACGGTATCGTGGAGATAACAAACCTCCTGAAGGACCCCTCCTGGGAGGGTATCCGCGG
TGAGGGCCAGCATGACCTTGTAATATTCATAGGCTGCATATACTACATCGCATCCCAGGGCCTATCAAGCCTCAAACACT
TCGCACCACATATAAAGACACTCACAATATGCAAGACATTCCACTCAAATGCAGATGCATCATTCCCGAACATGGATGAT
GATGAATGGTTCAGATACCTTGAGAAGATGTATGCTGAATGA

Upstream 100 bases:

>100_bases
AGGACATCCCGATAGTCTACAAGAGGGATGTCATGAAGATCCTTGAGGAGAAAAACTGGAAACCCAGGGAGCTTCCAAAG
GAACCCTCACTCCTGGAGAG

Downstream 100 bases:

>100_bases
TCAGGATAATGGAGGAATTCAATGTTTGAAGACATACCAGTCGATGTAAGTCCCATGCATGAGGGGGAGAGGATAAGATC
AGCCAACATGTTCGTTGAAC

Product: acetyl-CoA decarbonylase/synthase complex subunit epsilon

Products: CO2; AH2

Alternate protein names: ACDS complex subunit epsilon

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MIVLNDRIIPWQPTVIAGPKQAMLVTPETATMMIKKARRPLMVVGPLAKRQEVLEHTVKIIRHFDLPVVATADTYRALSE
AGIESEPHGIVEITNLLKDPSWEGIRGEGQHDLVIFIGCIYYIASQGLSSLKHFAPHIKTLTICKTFHSNADASFPNMDD
DEWFRYLEKMYAE

Sequences:

>Translated_173_residues
MIVLNDRIIPWQPTVIAGPKQAMLVTPETATMMIKKARRPLMVVGPLAKRQEVLEHTVKIIRHFDLPVVATADTYRALSE
AGIESEPHGIVEITNLLKDPSWEGIRGEGQHDLVIFIGCIYYIASQGLSSLKHFAPHIKTLTICKTFHSNADASFPNMDD
DEWFRYLEKMYAE
>Mature_173_residues
MIVLNDRIIPWQPTVIAGPKQAMLVTPETATMMIKKARRPLMVVGPLAKRQEVLEHTVKIIRHFDLPVVATADTYRALSE
AGIESEPHGIVEITNLLKDPSWEGIRGEGQHDLVIFIGCIYYIASQGLSSLKHFAPHIKTLTICKTFHSNADASFPNMDD
DEWFRYLEKMYAE

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably has a structural role in stabilizing the alpha-epsilon subcomponent of the ACDS complex by forming a structural link between the two a

COG id: COG1880

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase epsilon subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdhB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDE_METTH (O27744)

Other databases:

- EMBL:   AE000666
- PIR:   F69095
- RefSeq:   NP_276821.1
- ProteinModelPortal:   O27744
- SMR:   O27744
- STRING:   O27744
- GeneID:   1470794
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1709
- NMPDR:   fig|187420.1.peg.1676
- eggNOG:   arNOG08811
- HOGENOM:   HBG541140
- OMA:   WQPTVIA
- ProtClustDB:   PRK00945
- BioCyc:   MTHE187420:MTH1709-MONOMER
- HAMAP:   MF_01134
- InterPro:   IPR003704
- PIRSF:   PIRSF006035
- TIGRFAMs:   TIGR00315

Pfam domain/function: PF02552 CO_dh

EC number: 1.2.99.2

Molecular weight: Translated: 19558; Mature: 19558

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLNDRIIPWQPTVIAGPKQAMLVTPETATMMIKKARRPLMVVGPLAKRQEVLEHTVKI
CEEECCCCCCCCCCEEECCCCEEEECCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHH
IRHFDLPVVATADTYRALSEAGIESEPHGIVEITNLLKDPSWEGIRGEGQHDLVIFIGCI
HHHCCCCEEECHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
YYIASQGLSSLKHFAPHIKTLTICKTFHSNADASFPNMDDDEWFRYLEKMYAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVLNDRIIPWQPTVIAGPKQAMLVTPETATMMIKKARRPLMVVGPLAKRQEVLEHTVKI
CEEECCCCCCCCCCEEECCCCEEEECCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHH
IRHFDLPVVATADTYRALSEAGIESEPHGIVEITNLLKDPSWEGIRGEGQHDLVIFIGCI
HHHCCCCEEECHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
YYIASQGLSSLKHFAPHIKTLTICKTFHSNADASFPNMDDDEWFRYLEKMYAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CO; H2O; A

Specific reaction: CO + H2O + A = CO2 + AH2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463