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Identifier: 15679596

GI number: 15679596

Start: 1466744

End: 1467907

Strand: Direct

Name: Not Available

Synonym: MTH1601

Alternate gene names: NA

Gene position: 1466744-1467907 (Clockwise)

Preceding gene: 15679579

Following gene: 15679598

Centisome position: 83.75

GC content: 51.46

Gene sequence:

>1164_bases
TTGGAAATGGATGAAACACTGCTTATGATCCCCGGGCCGACGAGGGTGGCCCAGAGAGTCCTTAAGGCAATGTCAGAGAA
CATTGTTAACCACAGGAGCGCCCTCTTTGGCAGGATCCTGACTGAAACGACTGAGATGATGTCCGATGTTTTCAGGACCA
GCAATAAGTCTTACCTTCTGACGGGTTCAGGGACAGCTGCAATGGAAGCCGCAGTTGCAAACATTATAGAACCCGGCGAT
AAGATCCTGAATGTTGTTGGGGGTAAATTTGGTCAGAGGTTCGCCCAGATAGTGGAGGCCTTTGGAGGCGAATCCATCAC
CATAGACGTGGAGTGGGGTAAGGCCGTTAACCCCGATGACATTGGATACACCCTAGAGGAGAATGATGATATAAAGGCAG
TCACAGTAGTCCACAATGAGACATCAACAGGTGTTGCTAACCCCATCAGGGAGATAGGGAAGATAATGGACGACTACGAC
GCCCTCTACATAGTTGACACGGTTTCATCCCTGGGAGGGGATGAGGTCGATGTTGAGTCCTACGGCATAGACATCTGTGT
TACAGGTTCCCAGAAGTGCCTTGCAGCACCCCCGGGCATGGCAGCCATAACCCTCAGCAACGACGCCTGGAGGGTCATTG
AAGCTGTGGATAATCCCCGGACATACTACCTGAACCTCAAGAAGTACAGGAAGAGCGGTGACGCGGAGCCACCTGAGACA
CCATACACCCCTGCAGTTTCACTCATATACGCAATGCATGAGGCCCTCAAGGTTATAATGGAGGAGGGACTCAGCAACAG
GATAAAGAGGCACAAGATAGCTGCAGAGGCCACAAGGAATGCGGTGAAGGCCCTCGACCTTGAACTGTTCCCTGATGAAG
CAGTTTCATCAACAACGGTCACGGCTGTTAATCTCCCGGAGGGAGTTACAGATGGTGAACTGAGGGGGACAATGAGGAAC
AAGTACCATGTTGAGCTTGCAGGGGGACAGGACCACCTCAAGGGAAGGATATTCCGTATCGGTCACATGGGTAACATAAC
CCACAGGGAACTTATAACAACATTTTCAGCCCTTGAGATGACCCTCAGGGAGCTCGGATTTGAGGTTGAAATGGGAGAGG
CTGTTGCAGCAGTTGCAGACACCTACCTCCCTGAGGACCTCTAA

Upstream 100 bases:

>100_bases
CGGATTTACTGATGGCTGGCCGGGACTCATGTAAATCTTTTTAAATGGACAGATTAAAAATAGATACAGGTTATGAAATC
CACTTTAATCTGGAGGTTTT

Downstream 100 bases:

>100_bases
ATATCTATTTTTTCGCGGATTTCTCCTTTTTCTGGCGGACCCTAAAACATTCTCCACCCGGAATCACCATGGCCCCTGTT
CGTTGACGAAGAGCTCTCCG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MEMDETLLMIPGPTRVAQRVLKAMSENIVNHRSALFGRILTETTEMMSDVFRTSNKSYLLTGSGTAAMEAAVANIIEPGD
KILNVVGGKFGQRFAQIVEAFGGESITIDVEWGKAVNPDDIGYTLEENDDIKAVTVVHNETSTGVANPIREIGKIMDDYD
ALYIVDTVSSLGGDEVDVESYGIDICVTGSQKCLAAPPGMAAITLSNDAWRVIEAVDNPRTYYLNLKKYRKSGDAEPPET
PYTPAVSLIYAMHEALKVIMEEGLSNRIKRHKIAAEATRNAVKALDLELFPDEAVSSTTVTAVNLPEGVTDGELRGTMRN
KYHVELAGGQDHLKGRIFRIGHMGNITHRELITTFSALEMTLRELGFEVEMGEAVAAVADTYLPEDL

Sequences:

>Translated_387_residues
MEMDETLLMIPGPTRVAQRVLKAMSENIVNHRSALFGRILTETTEMMSDVFRTSNKSYLLTGSGTAAMEAAVANIIEPGD
KILNVVGGKFGQRFAQIVEAFGGESITIDVEWGKAVNPDDIGYTLEENDDIKAVTVVHNETSTGVANPIREIGKIMDDYD
ALYIVDTVSSLGGDEVDVESYGIDICVTGSQKCLAAPPGMAAITLSNDAWRVIEAVDNPRTYYLNLKKYRKSGDAEPPET
PYTPAVSLIYAMHEALKVIMEEGLSNRIKRHKIAAEATRNAVKALDLELFPDEAVSSTTVTAVNLPEGVTDGELRGTMRN
KYHVELAGGQDHLKGRIFRIGHMGNITHRELITTFSALEMTLRELGFEVEMGEAVAAVADTYLPEDL
>Mature_387_residues
MEMDETLLMIPGPTRVAQRVLKAMSENIVNHRSALFGRILTETTEMMSDVFRTSNKSYLLTGSGTAAMEAAVANIIEPGD
KILNVVGGKFGQRFAQIVEAFGGESITIDVEWGKAVNPDDIGYTLEENDDIKAVTVVHNETSTGVANPIREIGKIMDDYD
ALYIVDTVSSLGGDEVDVESYGIDICVTGSQKCLAAPPGMAAITLSNDAWRVIEAVDNPRTYYLNLKKYRKSGDAEPPET
PYTPAVSLIYAMHEALKVIMEEGLSNRIKRHKIAAEATRNAVKALDLELFPDEAVSSTTVTAVNLPEGVTDGELRGTMRN
KYHVELAGGQDHLKGRIFRIGHMGNITHRELITTFSALEMTLRELGFEVEMGEAVAAVADTYLPEDL

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=365, Percent_Identity=33.1506849315069, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17536281, Length=346, Percent_Identity=34.1040462427746, Blast_Score=177, Evalue=7e-45,
Organism=Saccharomyces cerevisiae, GI6321079, Length=361, Percent_Identity=27.9778393351801, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17530823, Length=343, Percent_Identity=31.4868804664723, Blast_Score=177, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42231; Mature: 42231

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMDETLLMIPGPTRVAQRVLKAMSENIVNHRSALFGRILTETTEMMSDVFRTSNKSYLL
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
TGSGTAAMEAAVANIIEPGDKILNVVGGKFGQRFAQIVEAFGGESITIDVEWGKAVNPDD
ECCCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
IGYTLEENDDIKAVTVVHNETSTGVANPIREIGKIMDDYDALYIVDTVSSLGGDEVDVES
CCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCEEHHH
YGIDICVTGSQKCLAAPPGMAAITLSNDAWRVIEAVDNPRTYYLNLKKYRKSGDAEPPET
CCEEEEEECCCCEEECCCCCEEEEECCCCEEHHHHCCCCEEEEEEHHHHHCCCCCCCCCC
PYTPAVSLIYAMHEALKVIMEEGLSNRIKRHKIAAEATRNAVKALDLELFPDEAVSSTTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCEE
TAVNLPEGVTDGELRGTMRNKYHVELAGGQDHLKGRIFRIGHMGNITHRELITTFSALEM
EEEECCCCCCCCHHHHCCCCEEEEEEECCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHH
TLRELGFEVEMGEAVAAVADTYLPEDL
HHHHCCCEEECCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEMDETLLMIPGPTRVAQRVLKAMSENIVNHRSALFGRILTETTEMMSDVFRTSNKSYLL
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
TGSGTAAMEAAVANIIEPGDKILNVVGGKFGQRFAQIVEAFGGESITIDVEWGKAVNPDD
ECCCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
IGYTLEENDDIKAVTVVHNETSTGVANPIREIGKIMDDYDALYIVDTVSSLGGDEVDVES
CCEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCEEHHH
YGIDICVTGSQKCLAAPPGMAAITLSNDAWRVIEAVDNPRTYYLNLKKYRKSGDAEPPET
CCEEEEEECCCCEEECCCCCEEEEECCCCEEHHHHCCCCEEEEEEHHHHHCCCCCCCCCC
PYTPAVSLIYAMHEALKVIMEEGLSNRIKRHKIAAEATRNAVKALDLELFPDEAVSSTTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCEE
TAVNLPEGVTDGELRGTMRNKYHVELAGGQDHLKGRIFRIGHMGNITHRELITTFSALEM
EEEECCCCCCCCHHHHCCCCEEEEEEECCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHH
TLRELGFEVEMGEAVAAVADTYLPEDL
HHHHCCCEEECCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]