Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15679524

GI number: 15679524

Start: 1387883

End: 1389244

Strand: Direct

Name: Not Available

Synonym: MTH1528

Alternate gene names: 15679524

Gene position: 1387883-1389244 (Clockwise)

Preceding gene: 15679523

Following gene: 15679525

Centisome position: 79.25

GC content: 51.25

Gene sequence:

>1362_bases
ATGGTGGTTGTTATGGGGACCTACTTCAATCCTGAAATAGAGACCATGGAACGTGGCGAACTGGACGCCCTTGTAGAGGA
GAGGATAAGGTACACAGTTAACTATGCATATGAAAACTCTCCCTTCTACAGCAAATGGTTCAGGGAGAACAATATCAAGC
CCTCAGATATAAAGAGTCATGAGGACCTAAGGGAGCTCCCTATAATAAGCGGTGAAACAGTAAGGAAAAACCAGCCACCT
GAAAAGGACAGATTTGAATTTAAATGCGCCCCCTGGGAGGAGATCTACACCATCCATGAGACCAGCGGCACCAGCGGAAG
ACCAAAGTCCTTCTTCCTCACATGGGGGGACTGGCAGAGGTACGCAGAGAAGTATGCGAGGTCCTTTGTATCCCAGGGAT
TTGAAACAGGTGACCGGGTCGTCGTATGCGCATCCTACGGCATGAACGTCGGGGCCAACACGATGACACTGGCAGCACAG
AAGATAGGAATGACAATAATACCCGAGGGCAAATGCACATTTCCTGTGAGGATAATGGAGAACTACCGGCCAACAGGGAT
AGTTGCAAACGTATTCAAACTGCTGAGGCTCGCAAGGCGAATGAAGGAGCAGGGAATTGATCCCAGGGAGTCAAGCATAA
AGAGACTGGTGGTTGGTGGTGAAAGCTTTGCGCCGGAATCAAGGGCATACGTCGAGGAACTGTGGGGAGTTGATGTCTAC
AACACCTATGGGAGCACCGAGGGGACCATGTGTGGGGAATGCCACATCAAGGAGGGACTCCACGTCCCCGAGGACCTCGT
ACACCTGGATGTCTATGACCCCAACCTCAGGGACTTCGTTGATGATGGGGAATGCGGCAGGATAGTCCTGACAACACTGC
TACCCGTTGGTGAGAGGACCGGCACACTCCTGCTCAACTATGACACCGAGGACACAACCGTGGTCATATCCAGGGACACG
TGCAGGTGTGGAAGGACCCACATGAGGATAATGAACCCTGAAAGGGAGGCAGAGACCTTCTGGATCTCCGGTCATCCATT
CAACCGGGTTGACGTTGAGGCAGCGGTTTTCCAGAGGGAGAACATGGATTACCTCACAGGGGAATATGAGGCCTTCCTCT
ACGGGGACGAGGATGAGGGCACAGTGACCATGAGGGTCTCCCTTGAATGTGAGGATCCAGGAAACTGCGCCAAGGAGATA
ATCCAGGAGAACTTTATAGGGGCCTTCTTCAAATATAAGAGGGACCTGCATGATGCCTACCTTGAGGGAACATTTGAGAT
AATATTCAACTTCGTAGGGCCAGGCGAACTCGAATTTTATAAGGTTAAGGGCAGGCCCAAGCGTATGGTTGATAGGAGAT
AG

Upstream 100 bases:

>100_bases
CGGACCGTCAGCAAATCTTTTTTCATTCTTGCTCTGATCATGTCGGGATGGAGATCATCAGCAAATCTTTATTTCATGGA
CGACAAACTAATGTCTGGAG

Downstream 100 bases:

>100_bases
TCCAGCTAAGGTTGGGATGTAGGGCAGACATCATCATGGACGGATAGTTTCAGGGAACTGAGCCTTCCTTCAGTGGATAG
CGAATTATATAATTAAAATG

Product: coenzyme F390 synthetase I

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MVVVMGTYFNPEIETMERGELDALVEERIRYTVNYAYENSPFYSKWFRENNIKPSDIKSHEDLRELPIISGETVRKNQPP
EKDRFEFKCAPWEEIYTIHETSGTSGRPKSFFLTWGDWQRYAEKYARSFVSQGFETGDRVVVCASYGMNVGANTMTLAAQ
KIGMTIIPEGKCTFPVRIMENYRPTGIVANVFKLLRLARRMKEQGIDPRESSIKRLVVGGESFAPESRAYVEELWGVDVY
NTYGSTEGTMCGECHIKEGLHVPEDLVHLDVYDPNLRDFVDDGECGRIVLTTLLPVGERTGTLLLNYDTEDTTVVISRDT
CRCGRTHMRIMNPEREAETFWISGHPFNRVDVEAAVFQRENMDYLTGEYEAFLYGDEDEGTVTMRVSLECEDPGNCAKEI
IQENFIGAFFKYKRDLHDAYLEGTFEIIFNFVGPGELEFYKVKGRPKRMVDRR

Sequences:

>Translated_453_residues
MVVVMGTYFNPEIETMERGELDALVEERIRYTVNYAYENSPFYSKWFRENNIKPSDIKSHEDLRELPIISGETVRKNQPP
EKDRFEFKCAPWEEIYTIHETSGTSGRPKSFFLTWGDWQRYAEKYARSFVSQGFETGDRVVVCASYGMNVGANTMTLAAQ
KIGMTIIPEGKCTFPVRIMENYRPTGIVANVFKLLRLARRMKEQGIDPRESSIKRLVVGGESFAPESRAYVEELWGVDVY
NTYGSTEGTMCGECHIKEGLHVPEDLVHLDVYDPNLRDFVDDGECGRIVLTTLLPVGERTGTLLLNYDTEDTTVVISRDT
CRCGRTHMRIMNPEREAETFWISGHPFNRVDVEAAVFQRENMDYLTGEYEAFLYGDEDEGTVTMRVSLECEDPGNCAKEI
IQENFIGAFFKYKRDLHDAYLEGTFEIIFNFVGPGELEFYKVKGRPKRMVDRR
>Mature_453_residues
MVVVMGTYFNPEIETMERGELDALVEERIRYTVNYAYENSPFYSKWFRENNIKPSDIKSHEDLRELPIISGETVRKNQPP
EKDRFEFKCAPWEEIYTIHETSGTSGRPKSFFLTWGDWQRYAEKYARSFVSQGFETGDRVVVCASYGMNVGANTMTLAAQ
KIGMTIIPEGKCTFPVRIMENYRPTGIVANVFKLLRLARRMKEQGIDPRESSIKRLVVGGESFAPESRAYVEELWGVDVY
NTYGSTEGTMCGECHIKEGLHVPEDLVHLDVYDPNLRDFVDDGECGRIVLTTLLPVGERTGTLLLNYDTEDTTVVISRDT
CRCGRTHMRIMNPEREAETFWISGHPFNRVDVEAAVFQRENMDYLTGEYEAFLYGDEDEGTVTMRVSLECEDPGNCAKEI
IQENFIGAFFKYKRDLHDAYLEGTFEIIFNFVGPGELEFYKVKGRPKRMVDRR

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=339, Percent_Identity=28.9085545722714, Blast_Score=130, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 52146; Mature: 52146

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVVMGTYFNPEIETMERGELDALVEERIRYTVNYAYENSPFYSKWFRENNIKPSDIKSH
CEEEEEECCCCCCCHHCCCCHHHHHHHHHEEEEEEEECCCCHHHHHHHCCCCCCCCCCCH
EDLRELPIISGETVRKNQPPEKDRFEFKCAPWEEIYTIHETSGTSGRPKSFFLTWGDWQR
HHHHHCCCCCCCCCCCCCCCCCCCCEEEECCHHHEEEEEECCCCCCCCCEEEEECCHHHH
YAEKYARSFVSQGFETGDRVVVCASYGMNVGANTMTLAAQKIGMTIIPEGKCTFPVRIME
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHEEEHHHCCEEEECCCCCEEEEEECC
NYRPTGIVANVFKLLRLARRMKEQGIDPRESSIKRLVVGGESFAPESRAYVEELWGVDVY
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEECCCCCCCCHHHHHHHHCCCEEE
NTYGSTEGTMCGECHIKEGLHVPEDLVHLDVYDPNLRDFVDDGECGRIVLTTLLPVGERT
ECCCCCCCCEECEEECCCCCCCCCHHEEEEEECCCHHHHCCCCCCCEEEEEEHHCCCCCC
GTLLLNYDTEDTTVVISRDTCRCGRTHMRIMNPEREAETFWISGHPFNRVDVEAAVFQRE
CEEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCCCCEEEECCCCCCCEEHHHHHHHHC
NMDYLTGEYEAFLYGDEDEGTVTMRVSLECEDPGNCAKEIIQENFIGAFFKYKRDLHDAY
CCCCCCCCEEEEEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LEGTFEIIFNFVGPGELEFYKVKGRPKRMVDRR
HCCEEEEEEEECCCCCEEEEEECCCCHHHCCCC
>Mature Secondary Structure
MVVVMGTYFNPEIETMERGELDALVEERIRYTVNYAYENSPFYSKWFRENNIKPSDIKSH
CEEEEEECCCCCCCHHCCCCHHHHHHHHHEEEEEEEECCCCHHHHHHHCCCCCCCCCCCH
EDLRELPIISGETVRKNQPPEKDRFEFKCAPWEEIYTIHETSGTSGRPKSFFLTWGDWQR
HHHHHCCCCCCCCCCCCCCCCCCCCEEEECCHHHEEEEEECCCCCCCCCEEEEECCHHHH
YAEKYARSFVSQGFETGDRVVVCASYGMNVGANTMTLAAQKIGMTIIPEGKCTFPVRIME
HHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHEEEHHHCCEEEECCCCCEEEEEECC
NYRPTGIVANVFKLLRLARRMKEQGIDPRESSIKRLVVGGESFAPESRAYVEELWGVDVY
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEECCCCCCCCHHHHHHHHCCCEEE
NTYGSTEGTMCGECHIKEGLHVPEDLVHLDVYDPNLRDFVDDGECGRIVLTTLLPVGERT
ECCCCCCCCEECEEECCCCCCCCCHHEEEEEECCCHHHHCCCCCCCEEEEEEHHCCCCCC
GTLLLNYDTEDTTVVISRDTCRCGRTHMRIMNPEREAETFWISGHPFNRVDVEAAVFQRE
CEEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCCCCEEEECCCCCCCEEHHHHHHHHC
NMDYLTGEYEAFLYGDEDEGTVTMRVSLECEDPGNCAKEIIQENFIGAFFKYKRDLHDAY
CCCCCCCCEEEEEECCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LEGTFEIIFNFVGPGELEFYKVKGRPKRMVDRR
HCCEEEEEEEECCCCCEEEEEECCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]