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Identifier: 15679269

GI number: 15679269

Start: 1149346

End: 1151049

Strand: Direct

Name: Not Available

Synonym: MTH1258

Alternate gene names: 15679269

Gene position: 1149346-1151049 (Clockwise)

Preceding gene: 15679268

Following gene: 15679274

Centisome position: 65.63

GC content: 49.06

Gene sequence:

>1704_bases
GTGACGCTGGCCCTTGGTGGTGTGGGGCTGATTGCATACGTTTTCAGCTTAACAGTTTCGGTGGTTACAATGACCCTGCA
GGATACCATATCAGGCGCCCGGATACGCAGGTTGATGCAGTCAATGAACAACCACTTCATTCTCTGTGGTTTTGGCCGTG
TCGGATCTGCTGTTTTTAAGGAGCTCCAGAAAAGGAACCAGAAGAGCATAATAATTGAAAAGGACCGTGAAATAGTTGAA
AAGGAACTATGGGATGATCCCAATGTCCTTGCGATACCCGAAAGCGCCGCAGATGAGGAGACTCTCAGGGCGGCCGGTAT
AAAACGGGCCAGGGGGGTTATAATAACAACAGGCGACGACGTCGACAACCTCTTCATAACACTGACCTGCAGGGAGCTTA
ACCCTGACATATGGATCGTGACAAGAGCAAGCAAGAGGGAAAACATCAAAAGGCTGTACCGTGCAGGGGCCAACCGGGTT
ATCTCACCCGAAATCAGTGGGGGAGAGGATATTTACTTCGCAGCCATGGAACCAACAATGGTGAAGATAACCGTTAAGCA
CGATGTTGACGACATTGGAAGGGAGGCCAGAATAATACTGAAACATGGCTGCACACTGGAGGACATAGAGTACCACCTCC
CTGAATTCAAGGAGCCCCTGGTGAGGAAGATCGGTGTGTCTGATGGCGGGGAACTTGAAAGGTTCCTGAAGATCCTTGAG
AGGGACCCGGCCAGGAAGAGTTCCCTTAAAAGGATCTATGAATCCGTCAGCGGCATACATTCCCATTGGATATCCGGGCC
TGACAGGGAGAGCATAGACGCTGTTATCGATGAACTCAAATCAGAGGGGATACTGCTTGGTGTGAACCTCAATGATGAGG
AGATAAAGGAGGTTGCAAGGAAACACGGCCGTCTCGTTGAAATAATAATAAAGCCTGAGATGAGCATAGTTGAAAACCAT
GGGGTCGATGACATCAGGAGAGAGGCCGAGATCATAATAAACCATGGCTGCACCATTGAGGATATAGAGTACTATCTCCC
GGGATTCTCAGAGCCCCTCAGAAGGAATGTTGGGGTTAGCTCCATGGAAGAAATCGACAGTTTCATGAAGACCCTCAAGA
GTGAACCCCGTAAACTTGAATCCCTTGACAGGCTCTACACGCTTTCAGGTGGTGGAATACACTCCCACCGGATTTCAGGG
CCCGACTCAAAGAGCCTTGAACTGGTTGAGAGAGAACTCAGGGAGGAGGGTTTCCTGATAGGGGTCAACCTGGAGCTCAG
TGAAATCAAGTCAATAATACAGGAGTCAGGCCGTGTTGTTGAGATGCTGCTCAAACATGACCTTGGAAACATGGACGACA
AGGAGATAATAATCCGGCGGGGCGGGCGTATCCTTGACTCAAAGCACTACCTCCCCGGAGTCAAGCAGGTCGTCACACGA
AACCTCAACATCAGGAACATGGATGATCTAAAGAGGTGCATGGAGGAACTGGAAAACCCTGATGCCCGAAGGTCACTCAA
GGCCCTCTACAGTATATCCCGGAATATACACTCCCACACAGTGGCTGCAGCCGACATTAAGATTATAATGAAAATTGAAG
ATGACCTCAGGAAAAGGGGTATACTCCTCGGTGTTAACCTCCGCGAGGACGAGATATGGGAAATAGTTGAAAGCGAAATG
ATGGAAAAATTCTGCATAGAATAA

Upstream 100 bases:

>100_bases
GCCTTGACTTCTACAACGCAGTCTACTTCACCATTATAACCATTGCAACCGTGGTTACGGGGATATAATCCCTGTTAACA
TACCCCAGAAGATATTCTCC

Downstream 100 bases:

>100_bases
AAAAAGGTCAACCCTGATAGGATCAGGGCATGGATAAAAAAATCAGAAGAGGTCATGGAGTTTTATCTTGTAGGCTCCCA
GGTTACCGCCATAGTTTCCT

Product: potassium channel related protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: MjK1 [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MTLALGGVGLIAYVFSLTVSVVTMTLQDTISGARIRRLMQSMNNHFILCGFGRVGSAVFKELQKRNQKSIIIEKDREIVE
KELWDDPNVLAIPESAADEETLRAAGIKRARGVIITTGDDVDNLFITLTCRELNPDIWIVTRASKRENIKRLYRAGANRV
ISPEISGGEDIYFAAMEPTMVKITVKHDVDDIGREARIILKHGCTLEDIEYHLPEFKEPLVRKIGVSDGGELERFLKILE
RDPARKSSLKRIYESVSGIHSHWISGPDRESIDAVIDELKSEGILLGVNLNDEEIKEVARKHGRLVEIIIKPEMSIVENH
GVDDIRREAEIIINHGCTIEDIEYYLPGFSEPLRRNVGVSSMEEIDSFMKTLKSEPRKLESLDRLYTLSGGGIHSHRISG
PDSKSLELVERELREEGFLIGVNLELSEIKSIIQESGRVVEMLLKHDLGNMDDKEIIIRRGGRILDSKHYLPGVKQVVTR
NLNIRNMDDLKRCMEELENPDARRSLKALYSISRNIHSHTVAAADIKIIMKIEDDLRKRGILLGVNLREDEIWEIVESEM
MEKFCIE

Sequences:

>Translated_567_residues
MTLALGGVGLIAYVFSLTVSVVTMTLQDTISGARIRRLMQSMNNHFILCGFGRVGSAVFKELQKRNQKSIIIEKDREIVE
KELWDDPNVLAIPESAADEETLRAAGIKRARGVIITTGDDVDNLFITLTCRELNPDIWIVTRASKRENIKRLYRAGANRV
ISPEISGGEDIYFAAMEPTMVKITVKHDVDDIGREARIILKHGCTLEDIEYHLPEFKEPLVRKIGVSDGGELERFLKILE
RDPARKSSLKRIYESVSGIHSHWISGPDRESIDAVIDELKSEGILLGVNLNDEEIKEVARKHGRLVEIIIKPEMSIVENH
GVDDIRREAEIIINHGCTIEDIEYYLPGFSEPLRRNVGVSSMEEIDSFMKTLKSEPRKLESLDRLYTLSGGGIHSHRISG
PDSKSLELVERELREEGFLIGVNLELSEIKSIIQESGRVVEMLLKHDLGNMDDKEIIIRRGGRILDSKHYLPGVKQVVTR
NLNIRNMDDLKRCMEELENPDARRSLKALYSISRNIHSHTVAAADIKIIMKIEDDLRKRGILLGVNLREDEIWEIVESEM
MEKFCIE
>Mature_566_residues
TLALGGVGLIAYVFSLTVSVVTMTLQDTISGARIRRLMQSMNNHFILCGFGRVGSAVFKELQKRNQKSIIIEKDREIVEK
ELWDDPNVLAIPESAADEETLRAAGIKRARGVIITTGDDVDNLFITLTCRELNPDIWIVTRASKRENIKRLYRAGANRVI
SPEISGGEDIYFAAMEPTMVKITVKHDVDDIGREARIILKHGCTLEDIEYHLPEFKEPLVRKIGVSDGGELERFLKILER
DPARKSSLKRIYESVSGIHSHWISGPDRESIDAVIDELKSEGILLGVNLNDEEIKEVARKHGRLVEIIIKPEMSIVENHG
VDDIRREAEIIINHGCTIEDIEYYLPGFSEPLRRNVGVSSMEEIDSFMKTLKSEPRKLESLDRLYTLSGGGIHSHRISGP
DSKSLELVERELREEGFLIGVNLELSEIKSIIQESGRVVEMLLKHDLGNMDDKEIIIRRGGRILDSKHYLPGVKQVVTRN
LNIRNMDDLKRCMEELENPDARRSLKALYSISRNIHSHTVAAADIKIIMKIEDDLRKRGILLGVNLREDEIWEIVESEMM
EKFCIE

Specific function: Potassium channel protein. Seems to conduct potassium at low membrane potentials [H]

COG id: COG1827

COG function: function code R; Predicted small molecule binding protein (contains 3H domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=167, Percent_Identity=28.1437125748503, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR003280
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 64327; Mature: 64196

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLALGGVGLIAYVFSLTVSVVTMTLQDTISGARIRRLMQSMNNHFILCGFGRVGSAVFK
CEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
ELQKRNQKSIIIEKDREIVEKELWDDPNVLAIPESAADEETLRAAGIKRARGVIITTGDD
HHHHCCCCCEEEECHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCEEEEECCCC
VDNLFITLTCRELNPDIWIVTRASKRENIKRLYRAGANRVISPEISGGEDIYFAAMEPTM
CCCEEEEEEEEECCCCEEEEECCHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEEECCEE
VKITVKHDVDDIGREARIILKHGCTLEDIEYHLPEFKEPLVRKIGVSDGGELERFLKILE
EEEEEECCHHHCCCHHEEHHHCCCCHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHH
RDPARKSSLKRIYESVSGIHSHWISGPDRESIDAVIDELKSEGILLGVNLNDEEIKEVAR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
KHGRLVEIIIKPEMSIVENHGVDDIRREAEIIINHGCTIEDIEYYLPGFSEPLRRNVGVS
HCCCEEEEEECCCHHHHHCCCHHHHHHHHHEEEECCCCHHHHHHHCCCCCHHHHHCCCCC
SMEEIDSFMKTLKSEPRKLESLDRLYTLSGGGIHSHRISGPDSKSLELVERELREEGFLI
HHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCEECCCCCCCCCCHHHHHHHHHHHCCEEE
GVNLELSEIKSIIQESGRVVEMLLKHDLGNMDDKEIIIRRGGRILDSKHYLPGVKQVVTR
EECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHCCCCEECCCCCCCHHHHHHHC
NLNIRNMDDLKRCMEELENPDARRSLKALYSISRNIHSHTVAAADIKIIMKIEDDLRKRG
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEECEEEEEEEHHHHHHCC
ILLGVNLREDEIWEIVESEMMEKFCIE
EEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLALGGVGLIAYVFSLTVSVVTMTLQDTISGARIRRLMQSMNNHFILCGFGRVGSAVFK
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
ELQKRNQKSIIIEKDREIVEKELWDDPNVLAIPESAADEETLRAAGIKRARGVIITTGDD
HHHHCCCCCEEEECHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCEEEEECCCC
VDNLFITLTCRELNPDIWIVTRASKRENIKRLYRAGANRVISPEISGGEDIYFAAMEPTM
CCCEEEEEEEEECCCCEEEEECCHHHHHHHHHHHCCCCCEECCCCCCCCEEEEEEECCEE
VKITVKHDVDDIGREARIILKHGCTLEDIEYHLPEFKEPLVRKIGVSDGGELERFLKILE
EEEEEECCHHHCCCHHEEHHHCCCCHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHH
RDPARKSSLKRIYESVSGIHSHWISGPDRESIDAVIDELKSEGILLGVNLNDEEIKEVAR
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHH
KHGRLVEIIIKPEMSIVENHGVDDIRREAEIIINHGCTIEDIEYYLPGFSEPLRRNVGVS
HCCCEEEEEECCCHHHHHCCCHHHHHHHHHEEEECCCCHHHHHHHCCCCCHHHHHCCCCC
SMEEIDSFMKTLKSEPRKLESLDRLYTLSGGGIHSHRISGPDSKSLELVERELREEGFLI
HHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCEECCCCCCCCCCHHHHHHHHHHHCCEEE
GVNLELSEIKSIIQESGRVVEMLLKHDLGNMDDKEIIIRRGGRILDSKHYLPGVKQVVTR
EECCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHCCCCEECCCCCCCHHHHHHHC
NLNIRNMDDLKRCMEELENPDARRSLKALYSISRNIHSHTVAAADIKIIMKIEDDLRKRG
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEEEEECEEEEEEEHHHHHHCC
ILLGVNLREDEIWEIVESEMMEKFCIE
EEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]