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Identifier: 15679221

GI number: 15679221

Start: 1112669

End: 1113691

Strand: Direct

Name: Not Available

Synonym: MTH1210

Alternate gene names: 15679221

Gene position: 1112669-1113691 (Clockwise)

Preceding gene: 15679220

Following gene: 15679225

Centisome position: 63.53

GC content: 43.3

Gene sequence:

>1023_bases
TTGTTCATGAAGAGCACAGAAAAGTGTCTTAAAGAATGGAATGCTATCGTAGAGGCCCTAGGACATGGAAAACAGACCAT
TCTGATCAGAAAATATAAGACAAACCTCAAAGAATTCCTGCTTTACCCCACAGTCAGCTATACCAATGAAAATGATTACC
TGAAAAGTTTCCAGGAAAAACACCACTCATTCGTTGAAAAATATAGCTTCCCCCATAAAGAGGGAGAAAAGACAGAGATC
AAATACTTTGCCACTGTAGAAAAGATCCTGGAAAGACCGCCTCGAATAATACCCTCAGAGAATTTCTACATCTGGAGAAG
GGGCCATGTAAAATCATATCTTAACGGGAAAAATGCCTACATATGGGTACTGAGGGTTTACAGACTGAAGAAACCCTACA
TGGCCGACCTCGCCTATGGACCGGGGGTCTACGCTAACCTGAAGGAACGGGTCTCACTGAAGGGCGCTGAACCGGTCCTC
ACAGATAAGGAATTCTCAGAAACATTAGAAAAACTAACTCCTGAAGAATCTCTACAATACGGTTATCAGACCCTGAGAGA
CGAGCTAGCCATGGAGTTGCTTGAAAATATTAGGTCCTGTTCCACAGGATTTTTCAAAAAAATGATAGTGGACCTCCTAT
TGAAGATGGGTTATGGCGGTTCACGAAAGGATGCAGATGAAGCCATAGAGAAGGGTGGAGACGGAGGCATAGAGGGTATT
ATAAAAGAGGATAAATTAGGTCTGGACACCATCTATATCCAGGCAAAGAGAGGGAGCATATCCAGACCTGAAATACAGAA
ATTTGCAAGTGCACTGGAGGGGCAAGCTAAAAAGGGAGTCTTTATCACAACATCCAGCTTTTCACGTGCTGCACAGGAAT
ACGCATCCAGCATCGATAACAGAATAGTCCTGATTGATGGAGATGAACTGGCCCAGCTGATGATCGACCACGACGTCGGT
GTATCAAAGGTGACATCCTACGATATCAAAAAAATAGACACAGACTACTTCTCAGAGGAATAA

Upstream 100 bases:

>100_bases
TTCAGCCCCTGTTAAACCGATGAGTATGAGATGTTAGAAAAAATAGGTGGAAAATACATCTGAAAATGAGTATGAAATGA
TAGAAGAAAACAGAGGATGA

Downstream 100 bases:

>100_bases
AAATCTGGAGAATATCAGAAACCAAATGAATATCCCTGTAACTGCAGAACATCCCCCTCTCCAATGTAATTTTTTTAATC
AAATAAAAACCACTCTTTCA

Product: mrr restriction system related protein

Products: NA

Alternate protein names: EcoKMrr [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MFMKSTEKCLKEWNAIVEALGHGKQTILIRKYKTNLKEFLLYPTVSYTNENDYLKSFQEKHHSFVEKYSFPHKEGEKTEI
KYFATVEKILERPPRIIPSENFYIWRRGHVKSYLNGKNAYIWVLRVYRLKKPYMADLAYGPGVYANLKERVSLKGAEPVL
TDKEFSETLEKLTPEESLQYGYQTLRDELAMELLENIRSCSTGFFKKMIVDLLLKMGYGGSRKDADEAIEKGGDGGIEGI
IKEDKLGLDTIYIQAKRGSISRPEIQKFASALEGQAKKGVFITTSSFSRAAQEYASSIDNRIVLIDGDELAQLMIDHDVG
VSKVTSYDIKKIDTDYFSEE

Sequences:

>Translated_340_residues
MFMKSTEKCLKEWNAIVEALGHGKQTILIRKYKTNLKEFLLYPTVSYTNENDYLKSFQEKHHSFVEKYSFPHKEGEKTEI
KYFATVEKILERPPRIIPSENFYIWRRGHVKSYLNGKNAYIWVLRVYRLKKPYMADLAYGPGVYANLKERVSLKGAEPVL
TDKEFSETLEKLTPEESLQYGYQTLRDELAMELLENIRSCSTGFFKKMIVDLLLKMGYGGSRKDADEAIEKGGDGGIEGI
IKEDKLGLDTIYIQAKRGSISRPEIQKFASALEGQAKKGVFITTSSFSRAAQEYASSIDNRIVLIDGDELAQLMIDHDVG
VSKVTSYDIKKIDTDYFSEE
>Mature_340_residues
MFMKSTEKCLKEWNAIVEALGHGKQTILIRKYKTNLKEFLLYPTVSYTNENDYLKSFQEKHHSFVEKYSFPHKEGEKTEI
KYFATVEKILERPPRIIPSENFYIWRRGHVKSYLNGKNAYIWVLRVYRLKKPYMADLAYGPGVYANLKERVSLKGAEPVL
TDKEFSETLEKLTPEESLQYGYQTLRDELAMELLENIRSCSTGFFKKMIVDLLLKMGYGGSRKDADEAIEKGGDGGIEGI
IKEDKLGLDTIYIQAKRGSISRPEIQKFASALEGQAKKGVFITTSSFSRAAQEYASSIDNRIVLIDGDELAQLMIDHDVG
VSKVTSYDIKKIDTDYFSEE

Specific function: Involved in the acceptance of foreign DNA which is modified. Restricts both adenine- and cytosine-methylated DNA [H]

COG id: COG1715

COG function: function code V; Restriction endonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790811, Length=198, Percent_Identity=42.9292929292929, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011856
- InterPro:   IPR011335
- InterPro:   IPR007560 [H]

Pfam domain/function: PF04471 Mrr_cat [H]

EC number: NA

Molecular weight: Translated: 38968; Mature: 38968

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMKSTEKCLKEWNAIVEALGHGKQTILIRKYKTNLKEFLLYPTVSYTNENDYLKSFQEK
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCHHHHHHCCCEECCCCHHHHHHHHHH
HHSFVEKYSFPHKEGEKTEIKYFATVEKILERPPRIIPSENFYIWRRGHVKSYLNGKNAY
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHCCCCCE
IWVLRVYRLKKPYMADLAYGPGVYANLKERVSLKGAEPVLTDKEFSETLEKLTPEESLQY
EEEEEHHHHCCCHHHHHCCCCCHHHCHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHH
GYQTLRDELAMELLENIRSCSTGFFKKMIVDLLLKMGYGGSRKDADEAIEKGGDGGIEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCC
IKEDKLGLDTIYIQAKRGSISRPEIQKFASALEGQAKKGVFITTSSFSRAAQEYASSIDN
EECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHCC
RIVLIDGDELAQLMIDHDVGVSKVTSYDIKKIDTDYFSEE
EEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MFMKSTEKCLKEWNAIVEALGHGKQTILIRKYKTNLKEFLLYPTVSYTNENDYLKSFQEK
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHCHHHHHHCCCEECCCCHHHHHHHHHH
HHSFVEKYSFPHKEGEKTEIKYFATVEKILERPPRIIPSENFYIWRRGHVKSYLNGKNAY
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHCCCCCE
IWVLRVYRLKKPYMADLAYGPGVYANLKERVSLKGAEPVLTDKEFSETLEKLTPEESLQY
EEEEEHHHHCCCHHHHHCCCCCHHHCHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHH
GYQTLRDELAMELLENIRSCSTGFFKKMIVDLLLKMGYGGSRKDADEAIEKGGDGGIEGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCC
IKEDKLGLDTIYIQAKRGSISRPEIQKFASALEGQAKKGVFITTSSFSRAAQEYASSIDN
EECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHCC
RIVLIDGDELAQLMIDHDVGVSKVTSYDIKKIDTDYFSEE
EEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1650347; 7610040; 9278503 [H]