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Identifier: 15679124

GI number: 15679124

Start: 1026143

End: 1026742

Strand: Direct

Name: Not Available

Synonym: MTH1113

Alternate gene names: NA

Gene position: 1026143-1026742 (Clockwise)

Preceding gene: 15679123

Following gene: 15679125

Centisome position: 58.59

GC content: 53.67

Gene sequence:

>600_bases
GTGCCCATCCAGCATGTGGAGAGTTTAATGGTATTTAATGATTCATTGGAGGTCAGTATAATGGATGTGAAGGTTTTGAG
GCTTGGTCACAGACCATCAAGGGATGCGAGGATCACGACACACGTATGCCTCACTGCAAGGGCCTTCGGTGCCTCGGAGG
TTATACTGAGTGGTGAGGAGGACCCTAAACTCATGGAGGGTGTTGAGGATGTTGTCAGGAGATGGGGTGGTCCCTTCAGT
GTGGTCTACCGGAGGAACTGGCAGGGTGTCATAGACTCCTGGAAGAAGGATGGTGGGGAGGTCATACACCTCACCATGTA
CGGTTTACCTGCCAGGGACGTTGTGCCCGGGATAATGGATAACGGCAAGGACAAGCTCATTGTGGTGGGGGGTGCAAGGG
TCCCCGGGAAGGTCTACAGCCTTGCAGACTACAACGTGGGGGTGACCAATCAGCCCCACTCTGAGGTCTCCTCCCTGGCG
GTGTTCATGCACATGCTCCTTGATGGGGCTGAATTCGACCTTAAATTTGAGGATGCCAGGATAGAGGTCATCCCCCAGGC
CAGGGGTAAAATGCTCAGGGAGATCGATGATGGCGATTAA

Upstream 100 bases:

>100_bases
CACGGGTGACGTGCTGGGGGCCTCGAATGAGGTGGGGAGGATGATGTCACTTCTGGGCCTCCTTGCGGCCATCAGATTAA
CGGGGCTGTAGGTAAAGGGG

Downstream 100 bases:

>100_bases
CATGATAAGCTGTGGATGGAGAGAGGATGATGCTGAGGGTGATTGATAACCTGATAGTCAGGGAGAAGCTCACCACCATA
AGGTGCAGGGGGATAGACCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MPIQHVESLMVFNDSLEVSIMDVKVLRLGHRPSRDARITTHVCLTARAFGASEVILSGEEDPKLMEGVEDVVRRWGGPFS
VVYRRNWQGVIDSWKKDGGEVIHLTMYGLPARDVVPGIMDNGKDKLIVVGGARVPGKVYSLADYNVGVTNQPHSEVSSLA
VFMHMLLDGAEFDLKFEDARIEVIPQARGKMLREIDDGD

Sequences:

>Translated_199_residues
MPIQHVESLMVFNDSLEVSIMDVKVLRLGHRPSRDARITTHVCLTARAFGASEVILSGEEDPKLMEGVEDVVRRWGGPFS
VVYRRNWQGVIDSWKKDGGEVIHLTMYGLPARDVVPGIMDNGKDKLIVVGGARVPGKVYSLADYNVGVTNQPHSEVSSLA
VFMHMLLDGAEFDLKFEDARIEVIPQARGKMLREIDDGD
>Mature_198_residues
PIQHVESLMVFNDSLEVSIMDVKVLRLGHRPSRDARITTHVCLTARAFGASEVILSGEEDPKLMEGVEDVVRRWGGPFSV
VYRRNWQGVIDSWKKDGGEVIHLTMYGLPARDVVPGIMDNGKDKLIVVGGARVPGKVYSLADYNVGVTNQPHSEVSSLAV
FMHMLLDGAEFDLKFEDARIEVIPQARGKMLREIDDGD

Specific function: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs [H]

COG id: COG1303

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aTrm56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002845
- ProDom:   PD016584 [H]

Pfam domain/function: PF01994 DUF127 [H]

EC number: NA

Molecular weight: Translated: 22102; Mature: 21970

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIQHVESLMVFNDSLEVSIMDVKVLRLGHRPSRDARITTHVCLTARAFGASEVILSGEE
CCHHHHHHHHEECCCCEEEEEEEEEEECCCCCCCCCEEEEEEEEEHHHCCCCEEEEECCC
DPKLMEGVEDVVRRWGGPFSVVYRRNWQGVIDSWKKDGGEVIHLTMYGLPARDVVPGIMD
CHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCEEEEEEECCCHHHHCCHHHC
NGKDKLIVVGGARVPGKVYSLADYNVGVTNQPHSEVSSLAVFMHMLLDGAEFDLKFEDAR
CCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCE
IEVIPQARGKMLREIDDGD
EEEECCHHHHHHHHCCCCC
>Mature Secondary Structure 
PIQHVESLMVFNDSLEVSIMDVKVLRLGHRPSRDARITTHVCLTARAFGASEVILSGEE
CHHHHHHHHEECCCCEEEEEEEEEEECCCCCCCCCEEEEEEEEEHHHCCCCEEEEECCC
DPKLMEGVEDVVRRWGGPFSVVYRRNWQGVIDSWKKDGGEVIHLTMYGLPARDVVPGIMD
CHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCEEEEEEECCCHHHHCCHHHC
NGKDKLIVVGGARVPGKVYSLADYNVGVTNQPHSEVSSLAVFMHMLLDGAEFDLKFEDAR
CCCCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCE
IEVIPQARGKMLREIDDGD
EEEECCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]