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Identifier: 15679116

GI number: 15679116

Start: 1018570

End: 1019676

Strand: Direct

Name: Not Available

Synonym: MTH1105

Alternate gene names: 15679116

Gene position: 1018570-1019676 (Clockwise)

Preceding gene: 15679115

Following gene: 15679118

Centisome position: 58.16

GC content: 54.02

Gene sequence:

>1107_bases
GTGTTTCAATTGGATAAGATAAAGATCGCGATAGTAGGTGTGGGAAACTGTGCCAGCTCCCTGATTCAGGGGATATACTA
TTACCGTAATAAGGGTGCCGGTGACTCGATAGGTCTCATGCACTGGGATATAGGCGGCTATGAACCCGGCGATATTGAGG
TCGTTGCTGCCTTCGATATTGATAGGCGGAAGGTTGGCCGGGATGTGAGTGAGGCCATATTCGCCCCACCAAACTGTACA
GCAGTCTTCTGCGATGACGTCCCGGAAATGGGTGTTGAGGTGTCCATGGGGCATGTCCTTGATGGTGTGGCCCCCCACAT
GAAGGACTACCCTGAAAAACAGACCTTCGTGGTTGCGGATGAGGAACCCGTGGATGTCGTTGAGGTCCTCCGGGAGAGCG
GGGCTGAGATACTCCTCAACTATCTGCCGGTGGGTTCAGAGGAGGCCGCAAGGTTCTATGCCCGCTGCGCCCTTGAGGCG
GGGGTAGCCTACATAAACAACATGCCTGTATTCATTGCAAGTGACCCTGAATGGGCTGCCAGATTCCAGGAGAAGGGCAT
ACCCATAGTCGGTGATGACATAAAGGCCCAGCTGGGGGCCACCATAACCCACAGGACCCTCACAAACCTCTTCAAGAGGA
GGGGTGTTAAACTCGACCGCACCTACCAGATAAACACTGGTGGGAACACTGATTTCCTCAACATGCTGAACCGTGACCGT
CTGGACTCAAAGAAGGAGTCCAAGACCGAAGCTGTCCAGTCAATACTTGGTGAGGACCGCCTGGATGATGAGAACATCCA
CATAGGGCCAAGTGACTACATACCCTGGCAGAAGGATAACAAGATCTGCTTCCTGAGGATGGAGGGCAGGCTCTTCGGGG
ACGTCCCCATGAACCTTGAGCTCAGGCTGAGTGTTGAGGATTCCCCCAACTCTGCGGGCTGTGTTATTGACGCCATAAGG
TGCTGCAAGCTGGCCATTGACCGGGGTATCGGTGGGCCCCTGACCTCCATATCATCCTATACAATGAAGCATCCCCCGGT
CCAGTACACTGACGACGTGGCAGCGCGTATGGTGGATGAATTCATTGCCGGTGAAAGGGAGAGATAA

Upstream 100 bases:

>100_bases
AGGGAAGGGCGAAACATTTAATAGTTTAATATGCAAATCTTAAAAAGTAGGTTGATCAATTTATAGCCTTGATTTTATGA
TTATCACAAGTCTCTGAAAG

Downstream 100 bases:

>100_bases
TCCCTTCACAGAATTCTCTTTTTTAAAAATACAACTTTAGAATCCCTGAAAATCTTCTTACCAGAATTCCATACATACAA
AAAAAACCTTAGAAACGATC

Product: hypothetical protein

Products: NA

Alternate protein names: IPS; Myo-inositol-1-phosphate synthase; MI-1-P synthase; MIP synthase [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MFQLDKIKIAIVGVGNCASSLIQGIYYYRNKGAGDSIGLMHWDIGGYEPGDIEVVAAFDIDRRKVGRDVSEAIFAPPNCT
AVFCDDVPEMGVEVSMGHVLDGVAPHMKDYPEKQTFVVADEEPVDVVEVLRESGAEILLNYLPVGSEEAARFYARCALEA
GVAYINNMPVFIASDPEWAARFQEKGIPIVGDDIKAQLGATITHRTLTNLFKRRGVKLDRTYQINTGGNTDFLNMLNRDR
LDSKKESKTEAVQSILGEDRLDDENIHIGPSDYIPWQKDNKICFLRMEGRLFGDVPMNLELRLSVEDSPNSAGCVIDAIR
CCKLAIDRGIGGPLTSISSYTMKHPPVQYTDDVAARMVDEFIAGERER

Sequences:

>Translated_368_residues
MFQLDKIKIAIVGVGNCASSLIQGIYYYRNKGAGDSIGLMHWDIGGYEPGDIEVVAAFDIDRRKVGRDVSEAIFAPPNCT
AVFCDDVPEMGVEVSMGHVLDGVAPHMKDYPEKQTFVVADEEPVDVVEVLRESGAEILLNYLPVGSEEAARFYARCALEA
GVAYINNMPVFIASDPEWAARFQEKGIPIVGDDIKAQLGATITHRTLTNLFKRRGVKLDRTYQINTGGNTDFLNMLNRDR
LDSKKESKTEAVQSILGEDRLDDENIHIGPSDYIPWQKDNKICFLRMEGRLFGDVPMNLELRLSVEDSPNSAGCVIDAIR
CCKLAIDRGIGGPLTSISSYTMKHPPVQYTDDVAARMVDEFIAGERER
>Mature_368_residues
MFQLDKIKIAIVGVGNCASSLIQGIYYYRNKGAGDSIGLMHWDIGGYEPGDIEVVAAFDIDRRKVGRDVSEAIFAPPNCT
AVFCDDVPEMGVEVSMGHVLDGVAPHMKDYPEKQTFVVADEEPVDVVEVLRESGAEILLNYLPVGSEEAARFYARCALEA
GVAYINNMPVFIASDPEWAARFQEKGIPIVGDDIKAQLGATITHRTLTNLFKRRGVKLDRTYQINTGGNTDFLNMLNRDR
LDSKKESKTEAVQSILGEDRLDDENIHIGPSDYIPWQKDNKICFLRMEGRLFGDVPMNLELRLSVEDSPNSAGCVIDAIR
CCKLAIDRGIGGPLTSISSYTMKHPPVQYTDDVAARMVDEFIAGERER

Specific function: Catalyzes the conversion of glucose 6-phosphate to 1D- myo-inositol 3-phosphate [H]

COG id: COG1260

COG function: function code I; Myo-inositol-1-phosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the myo-inositol-1-phosphate synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002587
- InterPro:   IPR017815
- InterPro:   IPR013021
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01658 Inos-1-P_synth; PF07994 NAD_binding_5 [H]

EC number: =5.5.1.4 [H]

Molecular weight: Translated: 40760; Mature: 40760

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQLDKIKIAIVGVGNCASSLIQGIYYYRNKGAGDSIGLMHWDIGGYEPGDIEVVAAFDI
CCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEECC
DRRKVGRDVSEAIFAPPNCTAVFCDDVPEMGVEVSMGHVLDGVAPHMKDYPEKQTFVVAD
CHHHHCCCHHHHHCCCCCCCEEEECCCCCCCCEEEHHHHHHCCCHHHHCCCCCCEEEEEC
EEPVDVVEVLRESGAEILLNYLPVGSEEAARFYARCALEAGVAYINNMPVFIASDPEWAA
CCCHHHHHHHHHCCHHEEHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHH
RFQEKGIPIVGDDIKAQLGATITHRTLTNLFKRRGVKLDRTYQINTGGNTDFLNMLNRDR
HHHHCCCCEECCCHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
LDSKKESKTEAVQSILGEDRLDDENIHIGPSDYIPWQKDNKICFLRMEGRLFGDVPMNLE
CCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCEEEECCCCCEE
LRLSVEDSPNSAGCVIDAIRCCKLAIDRGIGGPLTSISSYTMKHPPVQYTDDVAARMVDE
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHH
FIAGERER
HHCCCCCC
>Mature Secondary Structure
MFQLDKIKIAIVGVGNCASSLIQGIYYYRNKGAGDSIGLMHWDIGGYEPGDIEVVAAFDI
CCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEECC
DRRKVGRDVSEAIFAPPNCTAVFCDDVPEMGVEVSMGHVLDGVAPHMKDYPEKQTFVVAD
CHHHHCCCHHHHHCCCCCCCEEEECCCCCCCCEEEHHHHHHCCCHHHHCCCCCCEEEEEC
EEPVDVVEVLRESGAEILLNYLPVGSEEAARFYARCALEAGVAYINNMPVFIASDPEWAA
CCCHHHHHHHHHCCHHEEHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHH
RFQEKGIPIVGDDIKAQLGATITHRTLTNLFKRRGVKLDRTYQINTGGNTDFLNMLNRDR
HHHHCCCCEECCCHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
LDSKKESKTEAVQSILGEDRLDDENIHIGPSDYIPWQKDNKICFLRMEGRLFGDVPMNLE
CCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCEEEEEECCEEEECCCCCEE
LRLSVEDSPNSAGCVIDAIRCCKLAIDRGIGGPLTSISSYTMKHPPVQYTDDVAARMVDE
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHH
FIAGERER
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA