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Identifier: 15679027

GI number: 15679027

Start: 922858

End: 923871

Strand: Direct

Name: Not Available

Synonym: MTH1009

Alternate gene names: 15679027

Gene position: 922858-923871 (Clockwise)

Preceding gene: 15679026

Following gene: 15679028

Centisome position: 52.69

GC content: 52.47

Gene sequence:

>1014_bases
ATGATATCTGTAGCCATTAACGGGTATGGGACAATAGGAAAGAGAGTTGCTGATGCTGTAGCTGCCCAGGACGACATGAA
GGTCGCTGGTGTCAGCAAAACAAAACCTGATTTTGAGGCGAGGGTTGCAATCGAGAAGGGATACGACCTCTACGTCAGCA
TCCCTGAACGTGAGAAGCTCTTCGGCGAAGCCGGCATACCTGTGAGCGGTACCGTGGAGGATATGCTGGAGGAAGCAGAT
ATAGTGGTTGATGCAACACCTGAGGGTATAGGTGCAAAGAACCTTGAAATGTACAGGGAGAAGGGCATAAAGGCCATATT
CCAGGGCGGTGAAAAACACGACGCCATAGGATTATCCTTCAACTCATTTGCAAACTACGATGAATCCCTTGGAGCCGACT
ATACCCGTGTGGTTTCATGCAACACAACAGGACTCTGCAGAACCCTCAAACCCATCGATGACCTCTGCGGCATAAAGAAG
GTGAGGGCTGTTATGGTGAGGAGGGGTGCCGACCCCGTACAGGTCAAAAAGGGACCGATAAACGCCATAGTACCTAACCC
TCCAACCGTGCCATCACACCACGGCCCCGACCTCAAGACCGTCATGAAGGGCGTTAACATCCACACGGTGGCCCTCCTGG
TCCCAACAACACTGATGCACCAGCACAACATAATGGTTGAACTTGAGGATCCCGTTGAGGCCGATGAGATAAAGGCCCGG
CTCGATGAGACCACGAGGGTCATGCTTGTCAGGGCCTCTGAGGGTCTCGCATCAACGGCTGAGATAATGGAGTACGCCAA
GGAACTTGGAAGGTCAAGGAACGACCTCTTCGAGATACCTGTATGGGAGGAGTCAATAAACGTTGTTGACGGGGAACTCT
TCTATATGCAGGCCGTCCACCAGGAGTCAGATGCTGTGCCCGAGAGTGTGGATGCCATAAGGGCACTCCTGGAGCTCGAG
GAGGACAACATGAAGTCCATCATGAAGACCAACAGGGCCATGGGCATCCTCTAA

Upstream 100 bases:

>100_bases
ATATAAAATAATCCATTAAAAATAGTATCAGGTTAGGAATTTAAACTCAAAGAGGTTTCCCTGGGAACAGCGTTTTTCAG
GGGATAGGAGGTTTTTTTAA

Downstream 100 bases:

>100_bases
ATCTCCCCCTCTTTTTTATAGTGGTGTTATTTTTGATAAGGGTTGGTCCGGCTGGTAACCCTGTTGGTTACCGTGGAAGC
ACCGTCAATGTCTTCAGCAA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH; NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MISVAINGYGTIGKRVADAVAAQDDMKVAGVSKTKPDFEARVAIEKGYDLYVSIPEREKLFGEAGIPVSGTVEDMLEEAD
IVVDATPEGIGAKNLEMYREKGIKAIFQGGEKHDAIGLSFNSFANYDESLGADYTRVVSCNTTGLCRTLKPIDDLCGIKK
VRAVMVRRGADPVQVKKGPINAIVPNPPTVPSHHGPDLKTVMKGVNIHTVALLVPTTLMHQHNIMVELEDPVEADEIKAR
LDETTRVMLVRASEGLASTAEIMEYAKELGRSRNDLFEIPVWEESINVVDGELFYMQAVHQESDAVPESVDAIRALLELE
EDNMKSIMKTNRAMGIL

Sequences:

>Translated_337_residues
MISVAINGYGTIGKRVADAVAAQDDMKVAGVSKTKPDFEARVAIEKGYDLYVSIPEREKLFGEAGIPVSGTVEDMLEEAD
IVVDATPEGIGAKNLEMYREKGIKAIFQGGEKHDAIGLSFNSFANYDESLGADYTRVVSCNTTGLCRTLKPIDDLCGIKK
VRAVMVRRGADPVQVKKGPINAIVPNPPTVPSHHGPDLKTVMKGVNIHTVALLVPTTLMHQHNIMVELEDPVEADEIKAR
LDETTRVMLVRASEGLASTAEIMEYAKELGRSRNDLFEIPVWEESINVVDGELFYMQAVHQESDAVPESVDAIRALLELE
EDNMKSIMKTNRAMGIL
>Mature_337_residues
MISVAINGYGTIGKRVADAVAAQDDMKVAGVSKTKPDFEARVAIEKGYDLYVSIPEREKLFGEAGIPVSGTVEDMLEEAD
IVVDATPEGIGAKNLEMYREKGIKAIFQGGEKHDAIGLSFNSFANYDESLGADYTRVVSCNTTGLCRTLKPIDDLCGIKK
VRAVMVRRGADPVQVKKGPINAIVPNPPTVPSHHGPDLKTVMKGVNIHTVALLVPTTLMHQHNIMVELEDPVEADEIKAR
LDETTRVMLVRASEGLASTAEIMEYAKELGRSRNDLFEIPVWEESINVVDGELFYMQAVHQESDAVPESVDAIRALLELE
EDNMKSIMKTNRAMGIL

Specific function: Unknown

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G3P_METTH (O27090)

Other databases:

- EMBL:   AE000666
- PIR:   E69001
- RefSeq:   NP_276144.1
- ProteinModelPortal:   O27090
- SMR:   O27090
- STRING:   O27090
- GeneID:   1471417
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH1009
- NMPDR:   fig|187420.1.peg.999
- eggNOG:   arNOG04694
- HOGENOM:   HBG392099
- OMA:   HHGPDVQ
- ProtClustDB:   PRK04207
- BioCyc:   MTHE187420:MTH1009-MONOMER
- BRENDA:   1.2.1.59
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00559
- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006436
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF000149
- SMART:   SM00846
- TIGRFAMs:   TIGR01546

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N

EC number: =1.2.1.59

Molecular weight: Translated: 36837; Mature: 36837

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00071 GAPDH

Important sites: ACT_SITE 140-140 BINDING 110-110 BINDING 168-168 BINDING 301-301

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVAINGYGTIGKRVADAVAAQDDMKVAGVSKTKPDFEARVAIEKGYDLYVSIPEREKL
CEEEEEECCCHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEEEECCCEEEEECCCHHHH
FGEAGIPVSGTVEDMLEEADIVVDATPEGIGAKNLEMYREKGIKAIFQGGEKHDAIGLSF
HCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCCHHHHHHHHCHHHHHCCCCCCCEEEEEH
NSFANYDESLGADYTRVVSCNTTGLCRTLKPIDDLCGIKKVRAVMVRRGADPVQVKKGPI
HHHCCCCHHHCCCEEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCCC
NAIVPNPPTVPSHHGPDLKTVMKGVNIHTVALLVPTTLMHQHNIMVELEDPVEADEIKAR
CEECCCCCCCCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHCCCEEEEECCCCCHHHHHHH
LDETTRVMLVRASEGLASTAEIMEYAKELGRSRNDLFEIPVWEESINVVDGELFYMQAVH
HCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEECCHHHHHHHHH
QESDAVPESVDAIRALLELEEDNMKSIMKTNRAMGIL
HHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MISVAINGYGTIGKRVADAVAAQDDMKVAGVSKTKPDFEARVAIEKGYDLYVSIPEREKL
CEEEEEECCCHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEEEECCCEEEEECCCHHHH
FGEAGIPVSGTVEDMLEEADIVVDATPEGIGAKNLEMYREKGIKAIFQGGEKHDAIGLSF
HCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCCHHHHHHHHCHHHHHCCCCCCCEEEEEH
NSFANYDESLGADYTRVVSCNTTGLCRTLKPIDDLCGIKKVRAVMVRRGADPVQVKKGPI
HHHCCCCHHHCCCEEEEEEECCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCCC
NAIVPNPPTVPSHHGPDLKTVMKGVNIHTVALLVPTTLMHQHNIMVELEDPVEADEIKAR
CEECCCCCCCCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHCCCEEEEECCCCCHHHHHHH
LDETTRVMLVRASEGLASTAEIMEYAKELGRSRNDLFEIPVWEESINVVDGELFYMQAVH
HCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCEECCHHHHHHHHH
QESDAVPESVDAIRALLELEEDNMKSIMKTNRAMGIL
HHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463