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Identifier: 15679003

GI number: 15679003

Start: 897936

End: 899033

Strand: Direct

Name: Not Available

Synonym: MTH985

Alternate gene names: 15679003

Gene position: 897936-899033 (Clockwise)

Preceding gene: 15679002

Following gene: 15679004

Centisome position: 51.27

GC content: 48.18

Gene sequence:

>1098_bases
ATGTCTGATAGAGACTGGGAAACCCTCCGGGAAAAGATAATCGGATTCGGTGAGAAATCCGTAAGGAAGAGCTACTACCC
GAGACTTCAGGAGTCAATGGCCGAACTTGAAAGGTTCAGAAAACTCCTTGACTGCGCAGATGACGCCATATTCCTGGTTA
AAATCCCTGGTGGTGAACTCGTGGATGCCAACCGTTCAGCCTGTGTAATGCTAGGATACTCCACCAGGGACATCCCGGGA
CACATGGTATACGATCTCCTGCCAGGGGAACTCCACAATGTATTCCGTGGAATACTGGAGGGTGATGAAGACAGGGTGAC
CATGGATGGCCGTTTACTTAAGAGGGACGGCGATGAGGTGCCCGTTGAGATAAAGGTAAACATCCTTGATTTTAAGGGTG
ATAGATACGCTGTGCTCGTTGCCAGGGATATAAGCGAGAGGCTGAGGATGGAGTCAGAGCTGATGAAATCCCTCAGGGAG
AATGAGGTCCTTCTGAGTGAGATACACCACAGGGTCAAGAACAACCTCCAGATAATATCAAGCCTTCTGAGCCTCCAGAG
CCATGGTATCGATGACCCATCATGCAGGTCTCTTCTTTCAGAGAGCCAGGACAGGATAAGGTCAATGGCACTCATACATG
AACAGCTCTACCGCTCAGGGGACTTCAGCTCCATAGAATTCTCATCATATGCCTCAAGGCTCCTCAAGAACCTCAAAAGA
TCATACGCCCCCGGGAAGAATATCGAGCTATCACTGGACACCGAAAACCTGAAACTCAGCCTTGAGACATCAATACCCCT
TGGCCTCATGCTCAGCGAGCTTGTGACCAATGCCCTCAAACATGCCTTTAAGGGAAGAGATAGTGGTAATATAATTGTTA
AATTTAAAAAGGATGGTGATTACTGTGTCCTTGAGGTCAGGGATGATGGTGTGGGTTTCAATGAGGAGAAGATCAGGAAC
AGCACCTCACTGGGCTTTAGACTTGTTGAAATACTCACAGAACAGCTGGACGGATCACTGACATACTCCGGAGAGAACGG
AGGACTTTTCAGAATAAGGTTCAGAGAACCCCTCTACAAGGACAGACTGACCAATTAA

Upstream 100 bases:

>100_bases
GGCCTCAATGAAGGACCCCTGCATTGTAACAAACCCTGTACGGCCCTCAATTGAAGATGTTGAGGCCATATTCAGGAGGG
CCCTCTGAGGTGCTGGTGAA

Downstream 100 bases:

>100_bases
ATACAATTAACATTTTTAATGTTCTGAGAGGATTATACACCTTATACCGTCTCAAGCTTTATTAAAGGCTTGAAGGGTTA
AATAAAGGTTTTTGTATCTC

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSDRDWETLREKIIGFGEKSVRKSYYPRLQESMAELERFRKLLDCADDAIFLVKIPGGELVDANRSACVMLGYSTRDIPG
HMVYDLLPGELHNVFRGILEGDEDRVTMDGRLLKRDGDEVPVEIKVNILDFKGDRYAVLVARDISERLRMESELMKSLRE
NEVLLSEIHHRVKNNLQIISSLLSLQSHGIDDPSCRSLLSESQDRIRSMALIHEQLYRSGDFSSIEFSSYASRLLKNLKR
SYAPGKNIELSLDTENLKLSLETSIPLGLMLSELVTNALKHAFKGRDSGNIIVKFKKDGDYCVLEVRDDGVGFNEEKIRN
STSLGFRLVEILTEQLDGSLTYSGENGGLFRIRFREPLYKDRLTN

Sequences:

>Translated_365_residues
MSDRDWETLREKIIGFGEKSVRKSYYPRLQESMAELERFRKLLDCADDAIFLVKIPGGELVDANRSACVMLGYSTRDIPG
HMVYDLLPGELHNVFRGILEGDEDRVTMDGRLLKRDGDEVPVEIKVNILDFKGDRYAVLVARDISERLRMESELMKSLRE
NEVLLSEIHHRVKNNLQIISSLLSLQSHGIDDPSCRSLLSESQDRIRSMALIHEQLYRSGDFSSIEFSSYASRLLKNLKR
SYAPGKNIELSLDTENLKLSLETSIPLGLMLSELVTNALKHAFKGRDSGNIIVKFKKDGDYCVLEVRDDGVGFNEEKIRN
STSLGFRLVEILTEQLDGSLTYSGENGGLFRIRFREPLYKDRLTN
>Mature_364_residues
SDRDWETLREKIIGFGEKSVRKSYYPRLQESMAELERFRKLLDCADDAIFLVKIPGGELVDANRSACVMLGYSTRDIPGH
MVYDLLPGELHNVFRGILEGDEDRVTMDGRLLKRDGDEVPVEIKVNILDFKGDRYAVLVARDISERLRMESELMKSLREN
EVLLSEIHHRVKNNLQIISSLLSLQSHGIDDPSCRSLLSESQDRIRSMALIHEQLYRSGDFSSIEFSSYASRLLKNLKRS
YAPGKNIELSLDTENLKLSLETSIPLGLMLSELVTNALKHAFKGRDSGNIIVKFKKDGDYCVLEVRDDGVGFNEEKIRNS
TSLGFRLVEILTEQLDGSLTYSGENGGLFRIRFREPLYKDRLTN

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=268, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41616; Mature: 41485

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRDWETLREKIIGFGEKSVRKSYYPRLQESMAELERFRKLLDCADDAIFLVKIPGGEL
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCE
VDANRSACVMLGYSTRDIPGHMVYDLLPGELHNVFRGILEGDEDRVTMDGRLLKRDGDEV
EECCCCEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEEECCEEEECCCCCC
PVEIKVNILDFKGDRYAVLVARDISERLRMESELMKSLRENEVLLSEIHHRVKNNLQIIS
CEEEEEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
SLLSLQSHGIDDPSCRSLLSESQDRIRSMALIHEQLYRSGDFSSIEFSSYASRLLKNLKR
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHH
SYAPGKNIELSLDTENLKLSLETSIPLGLMLSELVTNALKHAFKGRDSGNIIVKFKKDGD
HCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
YCVLEVRDDGVGFNEEKIRNSTSLGFRLVEILTEQLDGSLTYSGENGGLFRIRFREPLYK
EEEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCHHH
DRLTN
HCCCC
>Mature Secondary Structure 
SDRDWETLREKIIGFGEKSVRKSYYPRLQESMAELERFRKLLDCADDAIFLVKIPGGEL
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCE
VDANRSACVMLGYSTRDIPGHMVYDLLPGELHNVFRGILEGDEDRVTMDGRLLKRDGDEV
EECCCCEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCCEEEECCEEEECCCCCC
PVEIKVNILDFKGDRYAVLVARDISERLRMESELMKSLRENEVLLSEIHHRVKNNLQIIS
CEEEEEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
SLLSLQSHGIDDPSCRSLLSESQDRIRSMALIHEQLYRSGDFSSIEFSSYASRLLKNLKR
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHH
SYAPGKNIELSLDTENLKLSLETSIPLGLMLSELVTNALKHAFKGRDSGNIIVKFKKDGD
HCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
YCVLEVRDDGVGFNEEKIRNSTSLGFRLVEILTEQLDGSLTYSGENGGLFRIRFREPLYK
EEEEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEECCCHHH
DRLTN
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]