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Identifier: 15678939

GI number: 15678939

Start: 836583

End: 837893

Strand: Direct

Name: Not Available

Synonym: MTH919

Alternate gene names: 15678939

Gene position: 836583-837893 (Clockwise)

Preceding gene: 15678938

Following gene: 15678950

Centisome position: 47.77

GC content: 44.32

Gene sequence:

>1311_bases
ATGAGCGTCTATAAAAATGTGACATGTCCCGTCTGCGGAGGGTCTTGTGATGACATAGAGGTTCTCTATGATGGGAAAAC
AATAAAAACAAGGAATGCTTGCAGGATGGGGAATGCAAAGTTTCAGGAGATGGTCAGCTCCCACAGAATACTTAGACCCC
AGATTAAAACTGAAAGTGGTTTCAGATCCGCAGAATGGGATGAAGCCCTTGACGCTGCAGCAGAGATACTTACAGAGTCA
AAAAGACCAACCCTATTCATGGGTAGTGAGATGTCAACTGAAGCCATGGCTGCAGGTCTTGAACTTGGTGAGTATCTAAA
TGCCATGGTGGATTCAAATGCAACCATATGTCATGGCCCCACATTAATGGGAATCCAGGAAGCTGGACAGAGCGCTGCTA
CGGCAGGTGAGATAAAGAATAGAGCTGACGTCATCATTTATTGGGGTACAAATGTTATGGACTCCATGCCTCGCCACATG
TCACGTTACAGCATATTCATGCGCGGATTTTTCAGAGAACGTGGTAAAAAAGATAGGACTGTCATCTCCGTGGATCCCCG
TGAAACAGCAACAACTAAAGCCTCCGATATCCATCTGCAGCTGAAACCAAACTCAGATTATGAACTCTTTTCAGCACTGC
TTACAGTTATAAGGGGCAATGAACCGCACAGGAGTATTGAGAGTATAACCGGGATATCAGTTGAAACCATAAAGGAAGTC
GCAGACATAATGCTGAATGCGCAGTTTGGAGCCATCTATGGGGGTCTTGGACTTGCATCATCAGAAGGTAAGCATAGAAA
CGTTGAGATGGTTCTCAAACTGGTAGCTGCACTTAATGAACACACCAAATTTACAATAGGAGCCATAAGAGGTCATTGTA
ATGTCGCAGGATTTAATCAGGTGGCTTCATGGGAATATGGTTTCCCCTTTGGTGTTGATTTTACAAGGGGTTATCCACGC
TACAACCCCGGAGAAACAACTATAGTCGATCTTCTCCAGAGAAAAGAATCCGATGCAGTCCTCGTTATATGTTCAGATCT
TGGAGCTCACCTCCCCAAAGAATGCGTTGAGTATATGAAAGAGATTCCTGTAATATGCATAGATATTGCCCCATGTCCAA
CAACACTTGTATCCGATGTTGTGATCCCTGGAGTTATTGATGCTATGGAGTCCAGCGGCACCTTCTACCGCTTTGACAAT
GTTCCCATCCACCATAAGGCATTCACAACATCACCATTCCCTGAAACAGAGAGCAACGAACATACTCTTAGACAGATCCT
TGAGAGGGTTAAATCAATTAAAGGCGAATAA

Upstream 100 bases:

>100_bases
CCCCAATGTATAAAGGAGTGCCGGTTTATCTTAGAAAGGCTTCACAAGGTGAAAGGATCCTGAGTGCCGAGGAACTTGTA
GAGGAATACGGGGTGGGAAA

Downstream 100 bases:

>100_bases
ATATCTGCTAACCATTTTTATTTTTTTCTCCTATGATACGGACATTCGTGGCTTTAATCAGAACTTGAAACTCTTCGCCC
GTTCTTATACCAAGCTCAGT

Product: molybdenum formylmethanofuran dehydrogenase, subunit B

Products: NA

Alternate protein names: Tungsten-containing formylmethanofuran dehydrogenase II subunit B [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSVYKNVTCPVCGGSCDDIEVLYDGKTIKTRNACRMGNAKFQEMVSSHRILRPQIKTESGFRSAEWDEALDAAAEILTES
KRPTLFMGSEMSTEAMAAGLELGEYLNAMVDSNATICHGPTLMGIQEAGQSAATAGEIKNRADVIIYWGTNVMDSMPRHM
SRYSIFMRGFFRERGKKDRTVISVDPRETATTKASDIHLQLKPNSDYELFSALLTVIRGNEPHRSIESITGISVETIKEV
ADIMLNAQFGAIYGGLGLASSEGKHRNVEMVLKLVAALNEHTKFTIGAIRGHCNVAGFNQVASWEYGFPFGVDFTRGYPR
YNPGETTIVDLLQRKESDAVLVICSDLGAHLPKECVEYMKEIPVICIDIAPCPTTLVSDVVIPGVIDAMESSGTFYRFDN
VPIHHKAFTTSPFPETESNEHTLRQILERVKSIKGE

Sequences:

>Translated_436_residues
MSVYKNVTCPVCGGSCDDIEVLYDGKTIKTRNACRMGNAKFQEMVSSHRILRPQIKTESGFRSAEWDEALDAAAEILTES
KRPTLFMGSEMSTEAMAAGLELGEYLNAMVDSNATICHGPTLMGIQEAGQSAATAGEIKNRADVIIYWGTNVMDSMPRHM
SRYSIFMRGFFRERGKKDRTVISVDPRETATTKASDIHLQLKPNSDYELFSALLTVIRGNEPHRSIESITGISVETIKEV
ADIMLNAQFGAIYGGLGLASSEGKHRNVEMVLKLVAALNEHTKFTIGAIRGHCNVAGFNQVASWEYGFPFGVDFTRGYPR
YNPGETTIVDLLQRKESDAVLVICSDLGAHLPKECVEYMKEIPVICIDIAPCPTTLVSDVVIPGVIDAMESSGTFYRFDN
VPIHHKAFTTSPFPETESNEHTLRQILERVKSIKGE
>Mature_435_residues
SVYKNVTCPVCGGSCDDIEVLYDGKTIKTRNACRMGNAKFQEMVSSHRILRPQIKTESGFRSAEWDEALDAAAEILTESK
RPTLFMGSEMSTEAMAAGLELGEYLNAMVDSNATICHGPTLMGIQEAGQSAATAGEIKNRADVIIYWGTNVMDSMPRHMS
RYSIFMRGFFRERGKKDRTVISVDPRETATTKASDIHLQLKPNSDYELFSALLTVIRGNEPHRSIESITGISVETIKEVA
DIMLNAQFGAIYGGLGLASSEGKHRNVEMVLKLVAALNEHTKFTIGAIRGHCNVAGFNQVASWEYGFPFGVDFTRGYPRY
NPGETTIVDLLQRKESDAVLVICSDLGAHLPKECVEYMKEIPVICIDIAPCPTTLVSDVVIPGVIDAMESSGTFYRFDNV
PIHHKAFTTSPFPETESNEHTLRQILERVKSIKGE

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). This enzyme is oxygen-labile [H]

COG id: COG1029

COG function: function code C; Formylmethanofuran dehydrogenase subunit B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fwdB family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=345, Percent_Identity=23.768115942029, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016457
- InterPro:   IPR006656 [H]

Pfam domain/function: PF00384 Molybdopterin [H]

EC number: =1.2.99.5 [H]

Molecular weight: Translated: 48123; Mature: 47992

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVYKNVTCPVCGGSCDDIEVLYDGKTIKTRNACRMGNAKFQEMVSSHRILRPQIKTESG
CCCCCCCCCCCCCCCCCCEEEEECCCEEECCCHHHCCCHHHHHHHHHCCEECCCCCCCCC
FRSAEWDEALDAAAEILTESKRPTLFMGSEMSTEAMAAGLELGEYLNAMVDSNATICHGP
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCC
TLMGIQEAGQSAATAGEIKNRADVIIYWGTNVMDSMPRHMSRYSIFMRGFFRERGKKDRT
CCHHHHHCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VISVDPRETATTKASDIHLQLKPNSDYELFSALLTVIRGNEPHRSIESITGISVETIKEV
EEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHH
ADIMLNAQFGAIYGGLGLASSEGKHRNVEMVLKLVAALNEHTKFTIGAIRGHCNVAGFNQ
HHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCH
VASWEYGFPFGVDFTRGYPRYNPGETTIVDLLQRKESDAVLVICSDLGAHLPKECVEYMK
HCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECHHCCCCHHHHHHHHH
EIPVICIDIAPCPTTLVSDVVIPGVIDAMESSGTFYRFDNVPIHHKAFTTSPFPETESNE
HCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCCCCCCCCCCCCCH
HTLRQILERVKSIKGE
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVYKNVTCPVCGGSCDDIEVLYDGKTIKTRNACRMGNAKFQEMVSSHRILRPQIKTESG
CCCCCCCCCCCCCCCCCEEEEECCCEEECCCHHHCCCHHHHHHHHHCCEECCCCCCCCC
FRSAEWDEALDAAAEILTESKRPTLFMGSEMSTEAMAAGLELGEYLNAMVDSNATICHGP
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCC
TLMGIQEAGQSAATAGEIKNRADVIIYWGTNVMDSMPRHMSRYSIFMRGFFRERGKKDRT
CCHHHHHCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
VISVDPRETATTKASDIHLQLKPNSDYELFSALLTVIRGNEPHRSIESITGISVETIKEV
EEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHH
ADIMLNAQFGAIYGGLGLASSEGKHRNVEMVLKLVAALNEHTKFTIGAIRGHCNVAGFNQ
HHHHHCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCH
VASWEYGFPFGVDFTRGYPRYNPGETTIVDLLQRKESDAVLVICSDLGAHLPKECVEYMK
HCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECHHCCCCHHHHHHHHH
EIPVICIDIAPCPTTLVSDVVIPGVIDAMESSGTFYRFDNVPIHHKAFTTSPFPETESNE
HCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCEECCCCCCCCCCCCCCCH
HTLRQILERVKSIKGE
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]