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Identifier: 15678938

GI number: 15678938

Start: 835384

End: 836586

Strand: Direct

Name: Not Available

Synonym: MTH918

Alternate gene names: 15678938

Gene position: 835384-836586 (Clockwise)

Preceding gene: 15678937

Following gene: 15678939

Centisome position: 47.7

GC content: 44.31

Gene sequence:

>1203_bases
ATGGGATTTGTGTTGGTACCAAAATCAGATTTCCAGATACCTCTGGAAGCAGATACCATAAGACCCGATCTGTTTGAAGG
GCTGGATCTTGATGAAATTCGTTCCCTTCAGGTATACGAAGGGAACATCAAAAGACCCCTAGGCGAATTTTTTGAGATAG
CGGAGACACCCCATGCAGATCAGTTAATACGGATCGATGGTGATGTCAGCAGGGTGAAGTATATCGGTTCAGGGATGAAA
TCCGGAAAAATCATCATAAACGGCGATGTTGGACTCCAGCTTGGCTGTGAAATGAAAGGCGGTGAAATAGAGGTAAATGG
AAATGTTTCTTCATGGATCGGCATGGAAATGCATGGTGGCACCATAAAAATTAATGGAAACGCGGGGGATTATGTTGGCT
GCGCATATAGGGGAGAGTGGCGTGGCATGAAAGGAGGTAAAATCATTATACAGGGTAATGCAGGGAACAATATTGGGGGT
GGTATGATGGCCGGAGAAATTTATATAGGTGGAGATGCAGGTAATTTCTGCGGCATCCGAATGAATGGGGGTGAAATAAC
AGTACGCGGGGATGCTGGAAGGGCCCCCGGGGCAGAGATGGTATCAGGTATCATCAAAATTCATGGCCGAATCTCCTCTC
TCCTCCCGGGATTCAAGGAGATCTCAACATTCAAAGAAGATGGATCCCTTATGATCCTATTCAAAGGAGATCTATCCGAA
AAAAATCCGGAGGGTAATCTATACATCAATTATAATAAGAACCTTCACATTCTAGAGAATGAGACCGATGAAGGGAGAGT
CATCACAAAAAAGGGAATTAAAGTAATCTACAACAGTGGAAGTACAATACGTGAAGGTCAGATAATAAAGGGAGGCAATA
AACTCACAGATGATTATATAGATGAATGTGCACGCTGCTGTATTAGTCCTGAAGACTATAAGCTCCTAGGTGAACCCGAA
AATGTTGTAGTATCCTCACATGGAAATGAAGTTGTTCTGAGAGCTGTTGAGGACCCTGGAATCCAGATGGGAACAATATT
CATACCCAGAGGTATATGGGCCAATGTGCTAACGCCACCGTATACCGAGTCAACCGGTTCCCCAATGTATAAAGGAGTGC
CGGTTTATCTTAGAAAGGCTTCACAAGGTGAAAGGATCCTGAGTGCCGAGGAACTTGTAGAGGAATACGGGGTGGGAAAA
TGA

Upstream 100 bases:

>100_bases
TAATTGAAATCTGTAATCTTTGCAACGAACCTTTCATAAAAAGAAACGAGCTGGATCTCTGTCCAGCTTGTCTGAAAAGA
TAAACATGAGGTGAAAAAAT

Downstream 100 bases:

>100_bases
GCGTCTATAAAAATGTGACATGTCCCGTCTGCGGAGGGTCTTGTGATGACATAGAGGTTCTCTATGATGGGAAAACAATA
AAAACAAGGAATGCTTGCAG

Product: molybdenum formylmethanofuran dehydrogenase, subunit C

Products: NA

Alternate protein names: Molybdenum-containing formylmethanofuran dehydrogenase I subunit C

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MGFVLVPKSDFQIPLEADTIRPDLFEGLDLDEIRSLQVYEGNIKRPLGEFFEIAETPHADQLIRIDGDVSRVKYIGSGMK
SGKIIINGDVGLQLGCEMKGGEIEVNGNVSSWIGMEMHGGTIKINGNAGDYVGCAYRGEWRGMKGGKIIIQGNAGNNIGG
GMMAGEIYIGGDAGNFCGIRMNGGEITVRGDAGRAPGAEMVSGIIKIHGRISSLLPGFKEISTFKEDGSLMILFKGDLSE
KNPEGNLYINYNKNLHILENETDEGRVITKKGIKVIYNSGSTIREGQIIKGGNKLTDDYIDECARCCISPEDYKLLGEPE
NVVVSSHGNEVVLRAVEDPGIQMGTIFIPRGIWANVLTPPYTESTGSPMYKGVPVYLRKASQGERILSAEELVEEYGVGK

Sequences:

>Translated_400_residues
MGFVLVPKSDFQIPLEADTIRPDLFEGLDLDEIRSLQVYEGNIKRPLGEFFEIAETPHADQLIRIDGDVSRVKYIGSGMK
SGKIIINGDVGLQLGCEMKGGEIEVNGNVSSWIGMEMHGGTIKINGNAGDYVGCAYRGEWRGMKGGKIIIQGNAGNNIGG
GMMAGEIYIGGDAGNFCGIRMNGGEITVRGDAGRAPGAEMVSGIIKIHGRISSLLPGFKEISTFKEDGSLMILFKGDLSE
KNPEGNLYINYNKNLHILENETDEGRVITKKGIKVIYNSGSTIREGQIIKGGNKLTDDYIDECARCCISPEDYKLLGEPE
NVVVSSHGNEVVLRAVEDPGIQMGTIFIPRGIWANVLTPPYTESTGSPMYKGVPVYLRKASQGERILSAEELVEEYGVGK
>Mature_399_residues
GFVLVPKSDFQIPLEADTIRPDLFEGLDLDEIRSLQVYEGNIKRPLGEFFEIAETPHADQLIRIDGDVSRVKYIGSGMKS
GKIIINGDVGLQLGCEMKGGEIEVNGNVSSWIGMEMHGGTIKINGNAGDYVGCAYRGEWRGMKGGKIIIQGNAGNNIGGG
MMAGEIYIGGDAGNFCGIRMNGGEITVRGDAGRAPGAEMVSGIIKIHGRISSLLPGFKEISTFKEDGSLMILFKGDLSEK
NPEGNLYINYNKNLHILENETDEGRVITKKGIKVIYNSGSTIREGQIIKGGNKLTDDYIDECARCCISPEDYKLLGEPEN
VVVSSHGNEVVLRAVEDPGIQMGTIFIPRGIWANVLTPPYTESTGSPMYKGVPVYLRKASQGERILSAEELVEEYGVGK

Specific function: Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). Can only oxidize formylmethanofuran. This enzyme is oxygen-labile

COG id: COG2218

COG function: function code C; Formylmethanofuran dehydrogenase subunit C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the molybdenum dinucleotide binding protein family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FMDC_METTH (O27002)

Other databases:

- EMBL:   AE000666
- PIR:   H69222
- RefSeq:   NP_276055.1
- ProteinModelPortal:   O27002
- STRING:   O27002
- GeneID:   1471326
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH918
- NMPDR:   fig|187420.1.peg.910
- eggNOG:   arNOG05644
- HOGENOM:   HBG541237
- OMA:   LECEVIT
- ProtClustDB:   CLSK878497
- BioCyc:   MetaCyc:FMDCMAUTO-MONOMER
- BioCyc:   MTHE187420:MTH918-MONOMER
- BRENDA:   1.2.99.5
- GO:   GO:0015948
- InterPro:   IPR009010
- InterPro:   IPR012048
- InterPro:   IPR017550
- InterPro:   IPR002489
- InterPro:   IPR006657
- Gene3D:   G3DSA:2.40.40.20
- Gene3D:   G3DSA:2.160.20.60
- PIRSF:   PIRSF036633
- TIGRFAMs:   TIGR03122

Pfam domain/function: PF01493 GXGXG; PF01568 Molydop_binding; SSF50692 Asp_decarb_fold; SSF69336 Glu_synthase_C

EC number: =1.2.99.5

Molecular weight: Translated: 43289; Mature: 43158

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFVLVPKSDFQIPLEADTIRPDLFEGLDLDEIRSLQVYEGNIKRPLGEFFEIAETPHAD
CCEEEECCCCCEEEEECCCCCCHHHCCCCHHHHCEEEEEECCCCCHHHHHHHHHCCCCCC
QLIRIDGDVSRVKYIGSGMKSGKIIINGDVGLQLGCEMKGGEIEVNGNVSSWIGMEMHGG
EEEEECCCHHHHHHHCCCCCCCEEEEECCCCEEEECEECCCEEEECCCCCCEEEEEECCC
TIKINGNAGDYVGCAYRGEWRGMKGGKIIIQGNAGNNIGGGMMAGEIYIGGDAGNFCGIR
EEEECCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCCEEEEE
MNGGEITVRGDAGRAPGAEMVSGIIKIHGRISSLLPGFKEISTFKEDGSLMILFKGDLSE
ECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCC
KNPEGNLYINYNKNLHILENETDEGRVITKKGIKVIYNSGSTIREGQIIKGGNKLTDDYI
CCCCCCEEEEECCCEEEEECCCCCCEEEEECCEEEEECCCCCEECCEEEECCCCCCHHHH
DECARCCISPEDYKLLGEPENVVVSSHGNEVVLRAVEDPGIQMGTIFIPRGIWANVLTPP
HHHHHHHCCCCCCEEECCCCEEEEECCCCEEEEEEECCCCEEEEEEEEECCCCCCCCCCC
YTESTGSPMYKGVPVYLRKASQGERILSAEELVEEYGVGK
CCCCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHHHCCCC
>Mature Secondary Structure 
GFVLVPKSDFQIPLEADTIRPDLFEGLDLDEIRSLQVYEGNIKRPLGEFFEIAETPHAD
CEEEECCCCCEEEEECCCCCCHHHCCCCHHHHCEEEEEECCCCCHHHHHHHHHCCCCCC
QLIRIDGDVSRVKYIGSGMKSGKIIINGDVGLQLGCEMKGGEIEVNGNVSSWIGMEMHGG
EEEEECCCHHHHHHHCCCCCCCEEEEECCCCEEEECEECCCEEEECCCCCCEEEEEECCC
TIKINGNAGDYVGCAYRGEWRGMKGGKIIIQGNAGNNIGGGMMAGEIYIGGDAGNFCGIR
EEEECCCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEECCCCCEEEEE
MNGGEITVRGDAGRAPGAEMVSGIIKIHGRISSLLPGFKEISTFKEDGSLMILFKGDLSE
ECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCC
KNPEGNLYINYNKNLHILENETDEGRVITKKGIKVIYNSGSTIREGQIIKGGNKLTDDYI
CCCCCCEEEEECCCEEEEECCCCCCEEEEECCEEEEECCCCCEECCEEEECCCCCCHHHH
DECARCCISPEDYKLLGEPENVVVSSHGNEVVLRAVEDPGIQMGTIFIPRGIWANVLTPP
HHHHHHHCCCCCCEEECCCCEEEEECCCCEEEEEEECCCCEEEEEEEEECCCCCCCCCCC
YTESTGSPMYKGVPVYLRKASQGERILSAEELVEEYGVGK
CCCCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463