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Identifier: 15678911

GI number: 15678911

Start: 809517

End: 810662

Strand: Direct

Name: Not Available

Synonym: MTH891

Alternate gene names: NA

Gene position: 809517-810662 (Clockwise)

Preceding gene: 15678910

Following gene: 15678912

Centisome position: 46.22

GC content: 51.31

Gene sequence:

>1146_bases
ATGGGAAAAGAAGAGATAAGCACAACTAAATACCTCATTCACGCTCAAATTAACGCTAATGGAATCGTAGAGAAACCAGA
TGTCGTGGGGGCGATATTCGGACAGACCGAAGGCCTCCTCAGCAACGACCTTGACCTCAGGGAATTCCAGAAAACAGGAA
GGATCGGTAGAATCAAGGTTAACATAACATCACGTGGTGGTAAATCAAAGGGGGAGATAATAATACCATCAAGCCTTGAC
CGTGTTGAAACCGCCATACTTGCGGCTTCCCTGGAAACGATAAACCGTGTCGGGCCATGCGAGGCCTACATCCAGGTCAC
CAAGGTCGAGGACGTCAGGGCAGTTAAACGTAAGAGGGTCGTTGAGAGGGCCAAGGAGATCTACGCAAGCATGATGGAGG
AGGTTACTCCCGAAAGCCTCAAGATGATCGAGGAGGTAAAGGAGGCCATGCGCGTCCATGAGATCACCGAGTACGGTGAG
GAGAAACTTCCGGCCGGCCCCAACGTTGAAACTTCAGACGCCATACTGGTGGTTGAGGGAAGATCAGACGTGCTCAACCT
CCTCAAGTACGGTATAAAGAACGCCATAGCAGTGGAGGGTGTCAGTGTACCGAAAACCGTGGCTGATTTAACCAGGAAAA
AGACCGTTACCGCCTTCGTTGATGGTGACAGGGGCGGTGAACTCATACTCAAGGAACTCCTCCAGGTTGGTGAAATAGAC
TACGTCACCAGGGCCCCTAAGGGCAAGGAGGTGGAGGACCTTGAGAAGGACGAGATAATGATGGCCCTGCGTAACAAGGT
GCCTGTTGAACAGTTCTACCATGACCTTGGAATGAAGAAGGAGAAGAAGAAGACAGAGGACAAGATGGTGCTCCTCCGTA
ACATCCTGAAGGAGCTTGAGGGCACCGGAAACGCCGAGATACTCGACGACGCCCTGAACATACTCAGGGAGGTTAAGGTG
GAGAACCTCTATGACGAACTGAGCAGGGTCAACAACCACCCCTACGCCGTGGTATTTGATGGTGTGATAACACAGCGCCT
GGTTGACCTCTCCTTCGAGAAGGGTCTCAGATACCTTGTGGCCGTTAGAAGCGGGGATATAGTTAAGAAACCCCACAACC
TCAAGCTTATAACCGGTCACACCTGA

Upstream 100 bases:

>100_bases
TGAAGCTGGAGGTATGCCCGTACCCCCTTGATAATATCTGAATGCTGTTATCATCACACTTCAATTTGATAACCAGTCAT
TCCTCAAAAGGAGGGTTTAC

Downstream 100 bases:

>100_bases
AATTAACAGAAGGCATCAAAAATGTATGTTGATATGAACCGTGAGTATCTGAAGGACATAAACACCACGGAAGACGTTAA
GATACCTGAGGATCCCCTTG

Product: DNA primase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MGKEEISTTKYLIHAQINANGIVEKPDVVGAIFGQTEGLLSNDLDLREFQKTGRIGRIKVNITSRGGKSKGEIIIPSSLD
RVETAILAASLETINRVGPCEAYIQVTKVEDVRAVKRKRVVERAKEIYASMMEEVTPESLKMIEEVKEAMRVHEITEYGE
EKLPAGPNVETSDAILVVEGRSDVLNLLKYGIKNAIAVEGVSVPKTVADLTRKKTVTAFVDGDRGGELILKELLQVGEID
YVTRAPKGKEVEDLEKDEIMMALRNKVPVEQFYHDLGMKKEKKKTEDKMVLLRNILKELEGTGNAEILDDALNILREVKV
ENLYDELSRVNNHPYAVVFDGVITQRLVDLSFEKGLRYLVAVRSGDIVKKPHNLKLITGHT

Sequences:

>Translated_381_residues
MGKEEISTTKYLIHAQINANGIVEKPDVVGAIFGQTEGLLSNDLDLREFQKTGRIGRIKVNITSRGGKSKGEIIIPSSLD
RVETAILAASLETINRVGPCEAYIQVTKVEDVRAVKRKRVVERAKEIYASMMEEVTPESLKMIEEVKEAMRVHEITEYGE
EKLPAGPNVETSDAILVVEGRSDVLNLLKYGIKNAIAVEGVSVPKTVADLTRKKTVTAFVDGDRGGELILKELLQVGEID
YVTRAPKGKEVEDLEKDEIMMALRNKVPVEQFYHDLGMKKEKKKTEDKMVLLRNILKELEGTGNAEILDDALNILREVKV
ENLYDELSRVNNHPYAVVFDGVITQRLVDLSFEKGLRYLVAVRSGDIVKKPHNLKLITGHT
>Mature_380_residues
GKEEISTTKYLIHAQINANGIVEKPDVVGAIFGQTEGLLSNDLDLREFQKTGRIGRIKVNITSRGGKSKGEIIIPSSLDR
VETAILAASLETINRVGPCEAYIQVTKVEDVRAVKRKRVVERAKEIYASMMEEVTPESLKMIEEVKEAMRVHEITEYGEE
KLPAGPNVETSDAILVVEGRSDVLNLLKYGIKNAIAVEGVSVPKTVADLTRKKTVTAFVDGDRGGELILKELLQVGEIDY
VTRAPKGKEVEDLEKDEIMMALRNKVPVEQFYHDLGMKKEKKKTEDKMVLLRNILKELEGTGNAEILDDALNILREVKVE
NLYDELSRVNNHPYAVVFDGVITQRLVDLSFEKGLRYLVAVRSGDIVKKPHNLKLITGHT

Specific function: Unknown

COG id: COG0358

COG function: function code L; DNA primase (bacterial type)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Toprim domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y891_METTH (O26977)

Other databases:

- EMBL:   AE000666
- PIR:   B69219
- RefSeq:   NP_276028.1
- ProteinModelPortal:   O26977
- SMR:   O26977
- STRING:   O26977
- GeneID:   1471299
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH891
- NMPDR:   fig|187420.1.peg.883
- eggNOG:   arNOG04629
- HOGENOM:   HBG541216
- OMA:   EMELIEY
- ProtClustDB:   PRK04031
- BioCyc:   MTHE187420:MTH891-MONOMER
- HAMAP:   MF_00007
- InterPro:   IPR006171
- InterPro:   IPR020607
- SMART:   SM00493

Pfam domain/function: PF01751 Toprim

EC number: NA

Molecular weight: Translated: 42516; Mature: 42385

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKEEISTTKYLIHAQINANGIVEKPDVVGAIFGQTEGLLSNDLDLREFQKTGRIGRIKV
CCCHHHCCEEEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHCCCEEEEEE
NITSRGGKSKGEIIIPSSLDRVETAILAASLETINRVGPCEAYIQVTKVEDVRAVKRKRV
EEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEEECHHHHHHHHHHHH
VERAKEIYASMMEEVTPESLKMIEEVKEAMRVHEITEYGEEKLPAGPNVETSDAILVVEG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCEEEEEEC
RSDVLNLLKYGIKNAIAVEGVSVPKTVADLTRKKTVTAFVDGDRGGELILKELLQVGEID
CHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCC
YVTRAPKGKEVEDLEKDEIMMALRNKVPVEQFYHDLGMKKEKKKTEDKMVLLRNILKELE
HHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GTGNAEILDDALNILREVKVENLYDELSRVNNHPYAVVFDGVITQRLVDLSFEKGLRYLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCEEEE
AVRSGDIVKKPHNLKLITGHT
EEECCCCEECCCCEEEEECCC
>Mature Secondary Structure 
GKEEISTTKYLIHAQINANGIVEKPDVVGAIFGQTEGLLSNDLDLREFQKTGRIGRIKV
CCHHHCCEEEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHCCCEEEEEE
NITSRGGKSKGEIIIPSSLDRVETAILAASLETINRVGPCEAYIQVTKVEDVRAVKRKRV
EEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEEECHHHHHHHHHHHH
VERAKEIYASMMEEVTPESLKMIEEVKEAMRVHEITEYGEEKLPAGPNVETSDAILVVEG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCEEEEEEC
RSDVLNLLKYGIKNAIAVEGVSVPKTVADLTRKKTVTAFVDGDRGGELILKELLQVGEID
CHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHCCCC
YVTRAPKGKEVEDLEKDEIMMALRNKVPVEQFYHDLGMKKEKKKTEDKMVLLRNILKELE
HHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GTGNAEILDDALNILREVKVENLYDELSRVNNHPYAVVFDGVITQRLVDLSFEKGLRYLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCEEEE
AVRSGDIVKKPHNLKLITGHT
EEECCCCEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463