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Identifier: 15678912

GI number: 15678912

Start: 810684

End: 812189

Strand: Direct

Name: Not Available

Synonym: MTH892

Alternate gene names: NA

Gene position: 810684-812189 (Clockwise)

Preceding gene: 15678911

Following gene: 15678913

Centisome position: 46.29

GC content: 52.52

Gene sequence:

>1506_bases
ATGTATGTTGATATGAACCGTGAGTATCTGAAGGACATAAACACCACGGAAGACGTTAAGATACCTGAGGATCCCCTTGA
AAGGGTTATAGGGCATGAAGATGTCATGCCAATGATAAAGATAGCTGCTAAGCAGCGTAGACACCTGCTACTTGTTGGAC
CGCCGGGCATAGGAAAATCACTCCTTGCCCAGGCAATATCCTTTCACCTGCCTGAACCATCTGAGGAGATAACGGTTGTC
CACAACCCTGAAAGGCCAGAGAGACCATTCGTTGAGATAAAAAACAGGAAAGAGATCGAGGATGAAATCCTTGAAATCGA
AAGGGCTGAGGGGGAACTCATAGACCCCCAGAGCGCCCCTGATGCTGTTGCAGAGCGCCTGGGCTTCAAGTGCATCCACT
GCGGGGAGTACAGCAGCGCCTATAACAGTATCTGCCCGCGGTGTGGTGGGGACAAGTTTTCACACATTAAGGCCCGGAGA
AAACATATCGGAGACCTCCTTGGAATGTTTGAGATGAGTTCAGGGAGCCTCAGCGTCCCCCAGAAGAGGGTGACAACGAC
CCGGATCATTGATGGTGTTGAGGAGGTTGTGATCTATGAGCGGGTTGGTGGTGAGGAGATCAAGGTACTTGATCAGAGGG
CCCTTGAAAAGCGAAGGCAGATCGTTGAGGAGAAGCCCAGGAACGTCATAGTACCCCTTGATAGAAAAACCTTTGTCCAG
GCCACAGGGGCCAGTGAAACCGAACTCCTGGGAGATGTCCGCCATGACCCCTACGGAGGTCACCCTGACCTTGGATCCCA
GCCCTATGAACGCGTTGTGCCGGGAGCCATCCATGAGGCCCATGAGGGTGTCCTCTTCATAGACGAGATAGTTCACATTG
CAGGCCTTCAGAGGTTCATATTCAGCGCAATGCAGGATAAAACATTCCCCATAGTCGGTAGGAACCCCCAGAGTGCTGGA
AGTTCCGTCAAGGTCGATGAGGTTCCATGTGACTTCATATTTGTCGGTGCCTGCAACATTGCGGACCTCCAGTACATACT
CCCCCCTCTGCGATCAAGGATCCAGGGAGAGGGTTATGAGCTTCTTCTGAACACCACAATGCCTGATACCGATGAGAACC
GGGCAAAGATAGCTCAGTTCGTTGCGCAGGAGATAGAGCTCGATGGAAAGATACCCCATGCCCGTGCCGCTGCCGTTGAA
CTCCTCATTGAAGAGGCTAGACGGAGGGCAAGGGCCGTGGATGATGTTGATAACGCCCTCACCCTCAGGCTCCGGGACCT
CGGAGGGGTTGTGAGGATGGCCGGGGACCTTGCAGTTATGGATGGAAGCCCCTACATTGAGACCCGGCACATGGAGGTCG
CCATAAGGAAGGCCGTTTCAGTTGAGGACCAGATAATAAGAAGATACAAGAGCTATGAGAAGGCCCTCGAGAAGGATCTA
TCAAGCTCCCAGAGGATGTCACAGCATGGATACAGCAGTGAGAACATAGACCGCAGCTACATGTAG

Upstream 100 bases:

>100_bases
CAGATACCTTGTGGCCGTTAGAAGCGGGGATATAGTTAAGAAACCCCACAACCTCAAGCTTATAACCGGTCACACCTGAA
ATTAACAGAAGGCATCAAAA

Downstream 100 bases:

>100_bases
TGAGAACTGCATCAGATGAGTTCGATGAGTGCATGATCCGCAAGGTTTAAGTGGATATTTATGGTAGATACCATGAATAT
GAAGAGGGAGTCAGAGGAAA

Product: ATP-dependent protease LA related protein

Products: NA

Alternate protein names: ATP-dependent protease La homolog

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MYVDMNREYLKDINTTEDVKIPEDPLERVIGHEDVMPMIKIAAKQRRHLLLVGPPGIGKSLLAQAISFHLPEPSEEITVV
HNPERPERPFVEIKNRKEIEDEILEIERAEGELIDPQSAPDAVAERLGFKCIHCGEYSSAYNSICPRCGGDKFSHIKARR
KHIGDLLGMFEMSSGSLSVPQKRVTTTRIIDGVEEVVIYERVGGEEIKVLDQRALEKRRQIVEEKPRNVIVPLDRKTFVQ
ATGASETELLGDVRHDPYGGHPDLGSQPYERVVPGAIHEAHEGVLFIDEIVHIAGLQRFIFSAMQDKTFPIVGRNPQSAG
SSVKVDEVPCDFIFVGACNIADLQYILPPLRSRIQGEGYELLLNTTMPDTDENRAKIAQFVAQEIELDGKIPHARAAAVE
LLIEEARRRARAVDDVDNALTLRLRDLGGVVRMAGDLAVMDGSPYIETRHMEVAIRKAVSVEDQIIRRYKSYEKALEKDL
SSSQRMSQHGYSSENIDRSYM

Sequences:

>Translated_501_residues
MYVDMNREYLKDINTTEDVKIPEDPLERVIGHEDVMPMIKIAAKQRRHLLLVGPPGIGKSLLAQAISFHLPEPSEEITVV
HNPERPERPFVEIKNRKEIEDEILEIERAEGELIDPQSAPDAVAERLGFKCIHCGEYSSAYNSICPRCGGDKFSHIKARR
KHIGDLLGMFEMSSGSLSVPQKRVTTTRIIDGVEEVVIYERVGGEEIKVLDQRALEKRRQIVEEKPRNVIVPLDRKTFVQ
ATGASETELLGDVRHDPYGGHPDLGSQPYERVVPGAIHEAHEGVLFIDEIVHIAGLQRFIFSAMQDKTFPIVGRNPQSAG
SSVKVDEVPCDFIFVGACNIADLQYILPPLRSRIQGEGYELLLNTTMPDTDENRAKIAQFVAQEIELDGKIPHARAAAVE
LLIEEARRRARAVDDVDNALTLRLRDLGGVVRMAGDLAVMDGSPYIETRHMEVAIRKAVSVEDQIIRRYKSYEKALEKDL
SSSQRMSQHGYSSENIDRSYM
>Mature_501_residues
MYVDMNREYLKDINTTEDVKIPEDPLERVIGHEDVMPMIKIAAKQRRHLLLVGPPGIGKSLLAQAISFHLPEPSEEITVV
HNPERPERPFVEIKNRKEIEDEILEIERAEGELIDPQSAPDAVAERLGFKCIHCGEYSSAYNSICPRCGGDKFSHIKARR
KHIGDLLGMFEMSSGSLSVPQKRVTTTRIIDGVEEVVIYERVGGEEIKVLDQRALEKRRQIVEEKPRNVIVPLDRKTFVQ
ATGASETELLGDVRHDPYGGHPDLGSQPYERVVPGAIHEAHEGVLFIDEIVHIAGLQRFIFSAMQDKTFPIVGRNPQSAG
SSVKVDEVPCDFIFVGACNIADLQYILPPLRSRIQGEGYELLLNTTMPDTDENRAKIAQFVAQEIELDGKIPHARAAAVE
LLIEEARRRARAVDDVDNALTLRLRDLGGVVRMAGDLAVMDGSPYIETRHMEVAIRKAVSVEDQIIRRYKSYEKALEKDL
SSSQRMSQHGYSSENIDRSYM

Specific function: Unknown

COG id: COG1067

COG function: function code O; Predicted ATP-dependent protease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S16 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LONH_METTH (O26978)

Other databases:

- EMBL:   AE000666
- PIR:   C69219
- RefSeq:   NP_276029.1
- ProteinModelPortal:   O26978
- SMR:   O26978
- STRING:   O26978
- GeneID:   1471300
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH892
- NMPDR:   fig|187420.1.peg.884
- eggNOG:   arNOG05052
- HOGENOM:   HBG539630
- OMA:   RHDPYGG
- ProtClustDB:   CLSK375631
- BioCyc:   MTHE187420:MTH892-MONOMER
- GO:   GO:0015979
- InterPro:   IPR003593
- InterPro:   IPR000523
- SMART:   SM00382

Pfam domain/function: PF01078 Mg_chelatase

EC number: 3.4.21.53

Molecular weight: Translated: 56285; Mature: 56285

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVDMNREYLKDINTTEDVKIPEDPLERVIGHEDVMPMIKIAAKQRRHLLLVGPPGIGKS
CEECCCHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHH
LLAQAISFHLPEPSEEITVVHNPERPERPFVEIKNRKEIEDEILEIERAEGELIDPQSAP
HHHHHHHHCCCCCCCCEEEEECCCCCCCCCEECCCHHHHHHHHHHHHHCCCCEECCCCCH
DAVAERLGFKCIHCGEYSSAYNSICPRCGGDKFSHIKARRKHIGDLLGMFEMSSGSLSVP
HHHHHHHCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QKRVTTTRIIDGVEEVVIYERVGGEEIKVLDQRALEKRRQIVEEKPRNVIVPLDRKTFVQ
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEE
ATGASETELLGDVRHDPYGGHPDLGSQPYERVVPGAIHEAHEGVLFIDEIVHIAGLQRFI
ECCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHHHHCCCEEHHHHHHHHHHHHHHH
FSAMQDKTFPIVGRNPQSAGSSVKVDEVPCDFIFVGACNIADLQYILPPLRSRIQGEGYE
HHHHCCCCCCEECCCCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEE
LLLNTTMPDTDENRAKIAQFVAQEIELDGKIPHARAAAVELLIEEARRRARAVDDVDNAL
EEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
TLRLRDLGGVVRMAGDLAVMDGSPYIETRHMEVAIRKAVSVEDQIIRRYKSYEKALEKDL
EEEEHHHCCHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSSQRMSQHGYSSENIDRSYM
HHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MYVDMNREYLKDINTTEDVKIPEDPLERVIGHEDVMPMIKIAAKQRRHLLLVGPPGIGKS
CEECCCHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHH
LLAQAISFHLPEPSEEITVVHNPERPERPFVEIKNRKEIEDEILEIERAEGELIDPQSAP
HHHHHHHHCCCCCCCCEEEEECCCCCCCCCEECCCHHHHHHHHHHHHHCCCCEECCCCCH
DAVAERLGFKCIHCGEYSSAYNSICPRCGGDKFSHIKARRKHIGDLLGMFEMSSGSLSVP
HHHHHHHCCEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QKRVTTTRIIDGVEEVVIYERVGGEEIKVLDQRALEKRRQIVEEKPRNVIVPLDRKTFVQ
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEE
ATGASETELLGDVRHDPYGGHPDLGSQPYERVVPGAIHEAHEGVLFIDEIVHIAGLQRFI
ECCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHCCHHHHHHCCCEEHHHHHHHHHHHHHHH
FSAMQDKTFPIVGRNPQSAGSSVKVDEVPCDFIFVGACNIADLQYILPPLRSRIQGEGYE
HHHHCCCCCCEECCCCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEE
LLLNTTMPDTDENRAKIAQFVAQEIELDGKIPHARAAAVELLIEEARRRARAVDDVDNAL
EEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
TLRLRDLGGVVRMAGDLAVMDGSPYIETRHMEVAIRKAVSVEDQIIRRYKSYEKALEKDL
EEEEHHHCCHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSSQRMSQHGYSSENIDRSYM
HHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463