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The map label for this gene is secD

Identifier: 15678869

GI number: 15678869

Start: 771150

End: 772361

Strand: Direct

Name: secD

Synonym: MTH849

Alternate gene names: 15678869

Gene position: 771150-772361 (Clockwise)

Preceding gene: 15678868

Following gene: 15678870

Centisome position: 44.03

GC content: 51.9

Gene sequence:

>1212_bases
ATGAACAGGAAGGTATCAAAGTTTCTTAAGGATTACAGGGTGATACTCCTCATAGTCCTCGTGGCGGCGAGTATCACTGC
AATATCAACCATGGGTATTCAGCAGGGACTTGACCTTCAGGGAGGGTCACTCATACAGATACAGCTCGAGAGGCCGGTTG
ATGCCGCCACCATGAACACCGTAACCAGTGTACTTGATAAGAGGCTCAACATATTCGGTGTGAAGGATGTGAAGGTGCGT
GCAAGCGGAGACCAGAACGTTATAGTTGAAATTGCTGGCGTCCAGCCGGACCAGGTCGCAGATATAGTTGGTAAACCCGG
TAAGTTTGAGGCAAAGATAGGTAACGAGACCGTTCTCACAGGCACAGATATTGTGAGCGTCCAGCCCCCCATAATAACCG
GGAATGAATGGGAGGTCCCATTCAGACTCTCAACAGATGGCGCCAGGAAGTTCGCAGAGGCAGCCAGGGGCAAGGCAGGA
GAACCCGTTAAGATGTACCTGGACGACCGCCTCATAACAGCCCCTGAAATATCAGCCGAGGTTGCCACTGGAAAACCGGT
CACAGATGTCAGGATAACAGGGGCAGAGAACAGCAAGGCAGAGGCCGAGGTCCAGGCGAAGGAGATAGAGACCCTCCTCA
AATCAGGTTCGCTGCCGGTTAAGGTTAAGATAGTCGGTGTGAGCAGCGTATCCCCTGAACTCGGAAAACAGTTCGCAGAG
GGTGCAGTGATCGCCGGGCTTCTCGCGGTTCTGGCAATAGCGGTGATACTCATAGTGAGGTACCGCAGCCCAATCCTCGT
CCTGCCAATATTTTTCACAACCCTCGCAGAGCTCCTGCTTATACTGGGAGCGGCTGCTGTTATCCGGTGGAACATCGACC
TTGCAGCCATAGCAGGTATACTGGCAGCGATAGGTACCGGGGTGGACGACCAGATAATCATAACAGACGAGGTCCTCTCG
GGTGAGGGCCGCAGAACAAGGAGGAAGTTCAGGATAAAGGACGCCTTCTTCATAATATTCGCATCAGCAGGTACCCTCAT
AGCTGCAATGCTTCCACTGGCATACATAGGCTTTTCAAGGGGTGCCACAGGTATAGGTCTCCTTGCTGGCTTTGCATTCA
CAACGGTCCTCGGAGTCATCATAGGAGTCTTCATCACAAGACCAGTGTATGCAAGATTCATTGAAACCTTCAACGTTGCT
GGAAGAAAATAG

Upstream 100 bases:

>100_bases
GTGATATAGCAGCAGTCCTGATAATTGGGCTCCTGGCGGATATCCTGACCACATGGCTCATGAACCTTGGAATTCTGAGA
TGGTACCTGGAGGTTAGATC

Downstream 100 bases:

>100_bases
GAGGGTCCTCACCAGTGAAGGGGAATAGGGGATGTCCCTTCCCCATTCAACGTCAGATAATAAGAGGGATGGATATGAAG
AAACCCTTTGAACTGAGGGT

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MNRKVSKFLKDYRVILLIVLVAASITAISTMGIQQGLDLQGGSLIQIQLERPVDAATMNTVTSVLDKRLNIFGVKDVKVR
ASGDQNVIVEIAGVQPDQVADIVGKPGKFEAKIGNETVLTGTDIVSVQPPIITGNEWEVPFRLSTDGARKFAEAARGKAG
EPVKMYLDDRLITAPEISAEVATGKPVTDVRITGAENSKAEAEVQAKEIETLLKSGSLPVKVKIVGVSSVSPELGKQFAE
GAVIAGLLAVLAIAVILIVRYRSPILVLPIFFTTLAELLLILGAAAVIRWNIDLAAIAGILAAIGTGVDDQIIITDEVLS
GEGRRTRRKFRIKDAFFIIFASAGTLIAAMLPLAYIGFSRGATGIGLLAGFAFTTVLGVIIGVFITRPVYARFIETFNVA
GRK

Sequences:

>Translated_403_residues
MNRKVSKFLKDYRVILLIVLVAASITAISTMGIQQGLDLQGGSLIQIQLERPVDAATMNTVTSVLDKRLNIFGVKDVKVR
ASGDQNVIVEIAGVQPDQVADIVGKPGKFEAKIGNETVLTGTDIVSVQPPIITGNEWEVPFRLSTDGARKFAEAARGKAG
EPVKMYLDDRLITAPEISAEVATGKPVTDVRITGAENSKAEAEVQAKEIETLLKSGSLPVKVKIVGVSSVSPELGKQFAE
GAVIAGLLAVLAIAVILIVRYRSPILVLPIFFTTLAELLLILGAAAVIRWNIDLAAIAGILAAIGTGVDDQIIITDEVLS
GEGRRTRRKFRIKDAFFIIFASAGTLIAAMLPLAYIGFSRGATGIGLLAGFAFTTVLGVIIGVFITRPVYARFIETFNVA
GRK
>Mature_403_residues
MNRKVSKFLKDYRVILLIVLVAASITAISTMGIQQGLDLQGGSLIQIQLERPVDAATMNTVTSVLDKRLNIFGVKDVKVR
ASGDQNVIVEIAGVQPDQVADIVGKPGKFEAKIGNETVLTGTDIVSVQPPIITGNEWEVPFRLSTDGARKFAEAARGKAG
EPVKMYLDDRLITAPEISAEVATGKPVTDVRITGAENSKAEAEVQAKEIETLLKSGSLPVKVKIVGVSSVSPELGKQFAE
GAVIAGLLAVLAIAVILIVRYRSPILVLPIFFTTLAELLLILGAAAVIRWNIDLAAIAGILAAIGTGVDDQIIITDEVLS
GEGRRTRRKFRIKDAFFIIFASAGTLIAAMLPLAYIGFSRGATGIGLLAGFAFTTVLGVIIGVFITRPVYARFIETFNVA
GRK

Specific function: Involved In Protein Export. [C]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family

Homologues:

Organism=Escherichia coli, GI1786609, Length=379, Percent_Identity=23.4828496042216, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y849_METTH (O26937)

Other databases:

- EMBL:   AE000666
- PIR:   C69213
- RefSeq:   NP_275986.1
- ProteinModelPortal:   O26937
- SMR:   O26937
- STRING:   O26937
- GeneID:   1471257
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH849
- NMPDR:   fig|187420.1.peg.841
- eggNOG:   arNOG05090
- HOGENOM:   HBG541641
- OMA:   AYGRIIM
- ProtClustDB:   PRK08343
- BioCyc:   MTHE187420:MTH849-MONOMER
- InterPro:   IPR022813
- InterPro:   IPR022646

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF

EC number: NA

Molecular weight: Translated: 42863; Mature: 42863

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc3dd57c)-; HASH(0xb0cad68)-; HASH(0xc4082ac)-; HASH(0xc614fe4)-; HASH(0xb2e6c88)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKVSKFLKDYRVILLIVLVAASITAISTMGIQQGLDLQGGSLIQIQLERPVDAATMNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHH
VTSVLDKRLNIFGVKDVKVRASGDQNVIVEIAGVQPDQVADIVGKPGKFEAKIGNETVLT
HHHHHHHCCCEEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHCCCCCEEEECCCCEEEE
GTDIVSVQPPIITGNEWEVPFRLSTDGARKFAEAARGKAGEPVKMYLDDRLITAPEISAE
CCCEEEECCCEEECCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCCE
VATGKPVTDVRITGAENSKAEAEVQAKEIETLLKSGSLPVKVKIVGVSSVSPELGKQFAE
ECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHC
GAVIAGLLAVLAIAVILIVRYRSPILVLPIFFTTLAELLLILGAAAVIRWNIDLAAIAGI
CHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCHHHEEECCHHHHHHHH
LAAIGTGVDDQIIITDEVLSGEGRRTRRKFRIKDAFFIIFASAGTLIAAMLPLAYIGFSR
HHHHCCCCCCEEEEEEHHHCCCCHHHHHHEEECEEEEEEEECHHHHHHHHHHHHHHHHCC
GATGIGLLAGFAFTTVLGVIIGVFITRPVYARFIETFNVAGRK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MNRKVSKFLKDYRVILLIVLVAASITAISTMGIQQGLDLQGGSLIQIQLERPVDAATMNT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHH
VTSVLDKRLNIFGVKDVKVRASGDQNVIVEIAGVQPDQVADIVGKPGKFEAKIGNETVLT
HHHHHHHCCCEEEEEEEEEEECCCCEEEEEEECCCCHHHHHHHCCCCCEEEECCCCEEEE
GTDIVSVQPPIITGNEWEVPFRLSTDGARKFAEAARGKAGEPVKMYLDDRLITAPEISAE
CCCEEEECCCEEECCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCCE
VATGKPVTDVRITGAENSKAEAEVQAKEIETLLKSGSLPVKVKIVGVSSVSPELGKQFAE
ECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHC
GAVIAGLLAVLAIAVILIVRYRSPILVLPIFFTTLAELLLILGAAAVIRWNIDLAAIAGI
CHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCHHHEEECCHHHHHHHH
LAAIGTGVDDQIIITDEVLSGEGRRTRRKFRIKDAFFIIFASAGTLIAAMLPLAYIGFSR
HHHHCCCCCCEEEEEEHHHCCCCHHHHHHEEECEEEEEEEECHHHHHHHHHHHHHHHHCC
GATGIGLLAGFAFTTVLGVIIGVFITRPVYARFIETFNVAGRK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9371463