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Identifier: 15678861

GI number: 15678861

Start: 764427

End: 765458

Strand: Direct

Name: Not Available

Synonym: MTH841

Alternate gene names: 15678861

Gene position: 764427-765458 (Clockwise)

Preceding gene: 15678852

Following gene: 15678863

Centisome position: 43.65

GC content: 45.16

Gene sequence:

>1032_bases
ATGTTGAGTTATCCCGGTGAGCTTCAAGGTTGCCGGGTAATCCTTTATTTAGTGGGTCATCACTTATATCTTATACCCAC
CACCATATCTATGTGTGGGTGTCCTGAGGAAGGTGCATATATGCGCAGACTGTGGGGTTATATCAGTATTATAACTGCAA
CGATTTTCTTTGGTATCTCTGCAACACTTGATAAGATAATGCTCTCCAGCATGCATCCTGTGACCATCGGGGCCTACACC
TACATAATTGCCGGAATCTTCCTCTTCTTCATAAGGGAAACCCCCCTTCGGGAGCATGTCCTTAACGCCATAAACAGAAA
AGGTGAAAGCGAAGCCAGGATAAAAAGGAATGATTACCTGATTCTTCTTCTTACAGCACTCCTGAGTACTGTGATAGCAC
CTCTCCTCTTCCTCACAGGACTGGGGGATACCACAGCGGTTAACGCATCACTCATACTGAACGTTGAGGTTCTCTTCATT
ATTTTACTGGGCTACCTAATTTTCAGGGAGACCCTTCAGCTGAAGGATTTCCTGGGGATAGTCCTCATCATACTGGGTGC
TGTGTACCTCTTAACTGAGGGTGATTTCAGTACCATTCTACGGAACGTTGCTGTTACCGGAAATTTCCTTGTGATGGCGG
CAGCGTTCTTCTGGAGCCTTGACACCGTCCTGAGCAAGTTTTTAAGCAGAAAAAGGGACCTTATATTTATATCTGGGGTT
AAAAGCTCTGTTGGGGGCTTTGTGCTCCTTATAATCATGCTTATTCTTGGTATAAACACTGAACTTCCCCTTGAAATGCT
CCCCTATGCACTCGGGGTTTCAGTCTTCAGCATTGGCTGCTCCTTCATACTCATCTACATCGCAATAAGGGAGATAGGTG
CTTCCATGGTCGGAGCCCTTTTTCCATTATCATCTCTTTTCGGGGCAATATTCGCATTTATAATCCTCAGAGAGCCATTC
TCGATCATGCAGGGAATTTCAGGGATTGTGATGCTTACAGGGGTCTTCATACTCTACTGGAACGGTAAGTAA

Upstream 100 bases:

>100_bases
GTACCTATGTATGCAACCTTCAGAGCTATCTTCCTCATAGGATCACCTGGTGTGGAGATAAGAGAAACCTGTAGTTAGAA
GAAGTAATATAATTTCTCAG

Downstream 100 bases:

>100_bases
GCTTATGTCCTGGAAAACTGAAATGTAATAAAGATCAGTGCCCCCTGAAAAAAGTGAAGAGAAATGAATCTGATCTCTAT
ATCCTGGCTCTCACATCAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLSYPGELQGCRVILYLVGHHLYLIPTTISMCGCPEEGAYMRRLWGYISIITATIFFGISATLDKIMLSSMHPVTIGAYT
YIIAGIFLFFIRETPLREHVLNAINRKGESEARIKRNDYLILLLTALLSTVIAPLLFLTGLGDTTAVNASLILNVEVLFI
ILLGYLIFRETLQLKDFLGIVLIILGAVYLLTEGDFSTILRNVAVTGNFLVMAAAFFWSLDTVLSKFLSRKRDLIFISGV
KSSVGGFVLLIIMLILGINTELPLEMLPYALGVSVFSIGCSFILIYIAIREIGASMVGALFPLSSLFGAIFAFIILREPF
SIMQGISGIVMLTGVFILYWNGK

Sequences:

>Translated_343_residues
MLSYPGELQGCRVILYLVGHHLYLIPTTISMCGCPEEGAYMRRLWGYISIITATIFFGISATLDKIMLSSMHPVTIGAYT
YIIAGIFLFFIRETPLREHVLNAINRKGESEARIKRNDYLILLLTALLSTVIAPLLFLTGLGDTTAVNASLILNVEVLFI
ILLGYLIFRETLQLKDFLGIVLIILGAVYLLTEGDFSTILRNVAVTGNFLVMAAAFFWSLDTVLSKFLSRKRDLIFISGV
KSSVGGFVLLIIMLILGINTELPLEMLPYALGVSVFSIGCSFILIYIAIREIGASMVGALFPLSSLFGAIFAFIILREPF
SIMQGISGIVMLTGVFILYWNGK
>Mature_343_residues
MLSYPGELQGCRVILYLVGHHLYLIPTTISMCGCPEEGAYMRRLWGYISIITATIFFGISATLDKIMLSSMHPVTIGAYT
YIIAGIFLFFIRETPLREHVLNAINRKGESEARIKRNDYLILLLTALLSTVIAPLLFLTGLGDTTAVNASLILNVEVLFI
ILLGYLIFRETLQLKDFLGIVLIILGAVYLLTEGDFSTILRNVAVTGNFLVMAAAFFWSLDTVLSKFLSRKRDLIFISGV
KSSVGGFVLLIIMLILGINTELPLEMLPYALGVSVFSIGCSFILIYIAIREIGASMVGALFPLSSLFGAIFAFIILREPF
SIMQGISGIVMLTGVFILYWNGK

Specific function: Unknown

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y841_METTH (O26929)

Other databases:

- EMBL:   AE000666
- PIR:   C69212
- RefSeq:   NP_275978.1
- GeneID:   1471249
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH841
- NMPDR:   fig|187420.1.peg.833
- eggNOG:   arNOG09878
- HOGENOM:   HBG727127
- OMA:   VWLHLTE
- ProtClustDB:   CLSK878491
- BioCyc:   MTHE187420:MTH841-MONOMER
- GO:   GO:0006810
- InterPro:   IPR000620

Pfam domain/function: PF00892 DUF6

EC number: NA

Molecular weight: Translated: 37840; Mature: 37840

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb9f0fec)-; HASH(0xb092540)-; HASH(0xb07e920)-; HASH(0x438c4100)-; HASH(0x438d0dc0)-; HASH(0xc3dd5d0)-; HASH(0xba9b874)-; HASH(0xb4f8bb8)-; HASH(0x4384b788)-; HASH(0xb345858)-; HASH(0x43869614)-;

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSYPGELQGCRVILYLVGHHLYLIPTTISMCGCPEEGAYMRRLWGYISIITATIFFGIS
CCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ATLDKIMLSSMHPVTIGAYTYIIAGIFLFFIRETPLREHVLNAINRKGESEARIKRNDYL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHCCCHH
ILLLTALLSTVIAPLLFLTGLGDTTAVNASLILNVEVLFIILLGYLIFRETLQLKDFLGI
HHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLIILGAVYLLTEGDFSTILRNVAVTGNFLVMAAAFFWSLDTVLSKFLSRKRDLIFISGV
HHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
KSSVGGFVLLIIMLILGINTELPLEMLPYALGVSVFSIGCSFILIYIAIREIGASMVGAL
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPLSSLFGAIFAFIILREPFSIMQGISGIVMLTGVFILYWNGK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCH
>Mature Secondary Structure
MLSYPGELQGCRVILYLVGHHLYLIPTTISMCGCPEEGAYMRRLWGYISIITATIFFGIS
CCCCCCCHHHHHHHHHHHHCCCEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ATLDKIMLSSMHPVTIGAYTYIIAGIFLFFIRETPLREHVLNAINRKGESEARIKRNDYL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHCCCHH
ILLLTALLSTVIAPLLFLTGLGDTTAVNASLILNVEVLFIILLGYLIFRETLQLKDFLGI
HHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLIILGAVYLLTEGDFSTILRNVAVTGNFLVMAAAFFWSLDTVLSKFLSRKRDLIFISGV
HHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
KSSVGGFVLLIIMLILGINTELPLEMLPYALGVSVFSIGCSFILIYIAIREIGASMVGAL
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPLSSLFGAIFAFIILREPFSIMQGISGIVMLTGVFILYWNGK
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371463