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The map label for this gene is moaC

Identifier: 15678831

GI number: 15678831

Start: 736054

End: 736533

Strand: Direct

Name: moaC

Synonym: MTH809

Alternate gene names: 15678831

Gene position: 736054-736533 (Clockwise)

Preceding gene: 15678830

Following gene: 15678832

Centisome position: 42.03

GC content: 49.79

Gene sequence:

>480_bases
GTGATGATAATGAAAGAATTCACCCATACAGATGAAAAGGGGGTCCGCATGGTTGATGTGGGCTCAAAGCCAGTTGTTAG
GAGAACCGCGACAGCCGAGGGCCATATACTCCTGCGTGAAGACACCATAAACTTAATCCGTGAAAAGAAGATTGAAAAGG
GGAACGTGCTTGCAACGGCCCAGATAGCAGCCATAGTGGCCGTTAAGAGGACCTGGGAGATAATACCCCTCTGCCATCCC
CTCCCCCTCACAGGTGTTGATGTTGAATTTGACCTGGATGATGACCGGATCACCGCCAGGGTTACTGTGAGATGCGATGG
GAAGACTGGTGTTGAGATGGAGGCCGTAACCGGTGTATCCGTTGCCCTGCTCACAATATGGGACATGGTTAAAAGTGTTG
AGAAGGACGATGATGGCCAGTACCCTGAAACGGCCATCAGCAACATAAGAGTCATTAAAAAGGAAAAGCTGGAACTCTGA

Upstream 100 bases:

>100_bases
AATTCACCCATGTATTTTAGAATCCATCAAAGAAATTCATGAGTGATGATAATGAAAGAATTCACCCATGTATTTTAGAA
TCCATCAAAGAAATTCATGA

Downstream 100 bases:

>100_bases
GGCGTGTTCATATGAAGTCCCTCCCACCTGAAATGAGACAGATCCTCGGGGACTGCTACCCCCATATAAGGGAGCTGAAC
CCTGCCCAGAGGAGTGCCAT

Product: putative molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MMIMKEFTHTDEKGVRMVDVGSKPVVRRTATAEGHILLREDTINLIREKKIEKGNVLATAQIAAIVAVKRTWEIIPLCHP
LPLTGVDVEFDLDDDRITARVTVRCDGKTGVEMEAVTGVSVALLTIWDMVKSVEKDDDGQYPETAISNIRVIKKEKLEL

Sequences:

>Translated_159_residues
MMIMKEFTHTDEKGVRMVDVGSKPVVRRTATAEGHILLREDTINLIREKKIEKGNVLATAQIAAIVAVKRTWEIIPLCHP
LPLTGVDVEFDLDDDRITARVTVRCDGKTGVEMEAVTGVSVALLTIWDMVKSVEKDDDGQYPETAISNIRVIKKEKLEL
>Mature_159_residues
MMIMKEFTHTDEKGVRMVDVGSKPVVRRTATAEGHILLREDTINLIREKKIEKGNVLATAQIAAIVAVKRTWEIIPLCHP
LPLTGVDVEFDLDDDRITARVTVRCDGKTGVEMEAVTGVSVALLTIWDMVKSVEKDDDGQYPETAISNIRVIKKEKLEL

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=136, Percent_Identity=47.0588235294118, Blast_Score=122, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=39.7350993377483, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI28574490, Length=152, Percent_Identity=45.3947368421053, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28574492, Length=140, Percent_Identity=46.4285714285714, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_METTH (O26900)

Other databases:

- EMBL:   AE000666
- PIR:   A69208
- RefSeq:   NP_275948.1
- ProteinModelPortal:   O26900
- SMR:   O26900
- STRING:   O26900
- GeneID:   1471217
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH809
- NMPDR:   fig|187420.1.peg.803
- eggNOG:   arNOG11144
- HOGENOM:   HBG605231
- OMA:   RIKEGTI
- PhylomeDB:   O26900
- ProtClustDB:   PRK12343
- BioCyc:   MTHE187420:MTH809-MONOMER
- HAMAP:   MF_01224_A
- InterPro:   IPR023045
- InterPro:   IPR023047
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17754; Mature: 17754

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIMKEFTHTDEKGVRMVDVGSKPVVRRTATAEGHILLREDTINLIREKKIEKGNVLATA
CEEECCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEEHHHHHHHHHHCCCCCCEEEHH
QIAAIVAVKRTWEIIPLCHPLPLTGVDVEFDLDDDRITARVTVRCDGKTGVEMEAVTGVS
HHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCCCEEEEEEEEEECCCCCCEEEECCCHH
VALLTIWDMVKSVEKDDDGQYPETAISNIRVIKKEKLEL
HHHHHHHHHHHHHCCCCCCCCCHHHHHHEEEEECCCCCC
>Mature Secondary Structure
MMIMKEFTHTDEKGVRMVDVGSKPVVRRTATAEGHILLREDTINLIREKKIEKGNVLATA
CEEECCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEEHHHHHHHHHHCCCCCCEEEHH
QIAAIVAVKRTWEIIPLCHPLPLTGVDVEFDLDDDRITARVTVRCDGKTGVEMEAVTGVS
HHHHHHHHHCCEEEEEECCCCCCCCCEEEEECCCCEEEEEEEEEECCCCCCEEEECCCHH
VALLTIWDMVKSVEKDDDGQYPETAISNIRVIKKEKLEL
HHHHHHHHHHHHHCCCCCCCCCHHHHHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463