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The map label for this gene is cbiD

Identifier: 15678830

GI number: 15678830

Start: 734821

End: 735915

Strand: Direct

Name: cbiD

Synonym: MTH808

Alternate gene names: 15678830

Gene position: 734821-735915 (Clockwise)

Preceding gene: 15678829

Following gene: 15678831

Centisome position: 41.96

GC content: 54.34

Gene sequence:

>1095_bases
ATGAATGATGAGAGGGTATTCGGGATTACAACTGGAACAGCTGCCACCGCAGCAGCCCTCGCCTCACTCCTGTGTCTGAA
GGGCTGTGAAGCCAGTAAGGTCAGGGTCAGGACCCCATCCGGGATCCTGGAGGTTGACGTTGAATATGTTGAGCGCATCT
CAGGTGACACCGCCAGGGCCTGTGTCATCAAGAGACCCTACCCTGACCCTGATGTCACCGTGAATCTTGAGATCATTTCC
ACTGTTCAGATCACAGGGACACCTGAAATCATGATAAGGGGTGGTGAGGGTGTTGGAATCGTCACAAAGCCCGGTCTCCA
GGTCCCCCCCGGAGAAGCAGCCATAAACCCTGTCCCCAGGAGGATGATAGAGGAGAACCTCAGGGAACACCTCAGGGATG
ATGAGGGCGCTGTGGTCACAGTGTCTGTGCCCGGGGGGGAGAGGATAGCCTCCAGGACCATGAACCCCCGTCTCGGGATC
ATCGGAGGTATCTCCATCCTTGGGACAACAGGCATAGCCAGGCCCATGTCCACCGAGGCATACCGGGAATCCCTTGCCTG
TCAGATCGATATCGCCACTGCCAGGGGTTTCAGGGAACTCGTATTTGTACCGGGTAACATAGGGGAGAGATTCGCCCGGG
AGTACTTTGAATCCATCGAGGATGAGAGGATAATCCAGATGGCCAACTTCCCAGGCTACATGCTGGAGGAGGCCGATGGC
AGGGGGGTTGAGCGGATAATACTCATGGGCCATGCAGGTAAACTGATCAAGCTGTCTGCCGGGATATTCCAGACCCGGAG
TTCAGATGCAGATGCCCGCCGCGAGATAATGGCTGCCCATGCAGCCCTCATGGGTGCCTCCAGAGATACGGTGACCAGAA
TATTCAACGATGGGACCGTGGAGGAGATGATATCTGAACTCGAGGGTGAAGGGTTGACAGGTAGGGTCTTCAACAGCATA
GCAGATGCCATAAGGGAGAGGTTCAATGAGAGGTTCTCCTTTGATACCGATGTCCTGATTTTCAGCCTGGATGGCCGGAT
CCTCAACTCAAACTTCAAGACTAAAAGGAACCACAGATTTACTGAAGTATTTTAG

Upstream 100 bases:

>100_bases
GTCAGGTTCGTTGGGGCCCCAAGCAGGGAAGAACTCTTTGAAGCCATAAATGATGAGATGGAATAACTTCTTTTTCAATT
AATTTTTAAGGATTTTTCTG

Downstream 100 bases:

>100_bases
AATCCATCAAAGAAATTCATGAGTGATGATAATGAAAGAATTCACCCATGTATTTTAGAATCCATCAAAGAAATTCATGA
GTGATGATAATGAAAGAATT

Product: cobalt-precorrin-6A synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MNDERVFGITTGTAATAAALASLLCLKGCEASKVRVRTPSGILEVDVEYVERISGDTARACVIKRPYPDPDVTVNLEIIS
TVQITGTPEIMIRGGEGVGIVTKPGLQVPPGEAAINPVPRRMIEENLREHLRDDEGAVVTVSVPGGERIASRTMNPRLGI
IGGISILGTTGIARPMSTEAYRESLACQIDIATARGFRELVFVPGNIGERFAREYFESIEDERIIQMANFPGYMLEEADG
RGVERIILMGHAGKLIKLSAGIFQTRSSDADARREIMAAHAALMGASRDTVTRIFNDGTVEEMISELEGEGLTGRVFNSI
ADAIRERFNERFSFDTDVLIFSLDGRILNSNFKTKRNHRFTEVF

Sequences:

>Translated_364_residues
MNDERVFGITTGTAATAAALASLLCLKGCEASKVRVRTPSGILEVDVEYVERISGDTARACVIKRPYPDPDVTVNLEIIS
TVQITGTPEIMIRGGEGVGIVTKPGLQVPPGEAAINPVPRRMIEENLREHLRDDEGAVVTVSVPGGERIASRTMNPRLGI
IGGISILGTTGIARPMSTEAYRESLACQIDIATARGFRELVFVPGNIGERFAREYFESIEDERIIQMANFPGYMLEEADG
RGVERIILMGHAGKLIKLSAGIFQTRSSDADARREIMAAHAALMGASRDTVTRIFNDGTVEEMISELEGEGLTGRVFNSI
ADAIRERFNERFSFDTDVLIFSLDGRILNSNFKTKRNHRFTEVF
>Mature_364_residues
MNDERVFGITTGTAATAAALASLLCLKGCEASKVRVRTPSGILEVDVEYVERISGDTARACVIKRPYPDPDVTVNLEIIS
TVQITGTPEIMIRGGEGVGIVTKPGLQVPPGEAAINPVPRRMIEENLREHLRDDEGAVVTVSVPGGERIASRTMNPRLGI
IGGISILGTTGIARPMSTEAYRESLACQIDIATARGFRELVFVPGNIGERFAREYFESIEDERIIQMANFPGYMLEEADG
RGVERIILMGHAGKLIKLSAGIFQTRSSDADARREIMAAHAALMGASRDTVTRIFNDGTVEEMISELEGEGLTGRVFNSI
ADAIRERFNERFSFDTDVLIFSLDGRILNSNFKTKRNHRFTEVF

Specific function: May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A

COG id: COG1903

COG function: function code H; Cobalamin biosynthesis protein CbiD

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBID_METTH (O26899)

Other databases:

- EMBL:   AE000666
- PIR:   H69207
- RefSeq:   NP_275947.1
- ProteinModelPortal:   O26899
- SMR:   O26899
- STRING:   O26899
- GeneID:   1471216
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH808
- NMPDR:   fig|187420.1.peg.802
- eggNOG:   arNOG08460
- HOGENOM:   HBG705387
- OMA:   TTGIARP
- ProtClustDB:   PRK00075
- BioCyc:   MTHE187420:MTH808-MONOMER
- HAMAP:   MF_00787
- InterPro:   IPR002748
- PIRSF:   PIRSF026782
- TIGRFAMs:   TIGR00312

Pfam domain/function: PF01888 CbiD; SSF111342 Cbl_biosynth_CbiD

EC number: NA

Molecular weight: Translated: 39809; Mature: 39809

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDERVFGITTGTAATAAALASLLCLKGCEASKVRVRTPSGILEVDVEYVERISGDTARA
CCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEHHHHHHHCCCCEEE
CVIKRPYPDPDVTVNLEIISTVQITGTPEIMIRGGEGVGIVTKPGLQVPPGEAAINPVPR
EEEECCCCCCCCEEEEEEEEEEEEECCCEEEEECCCCEEEEECCCCCCCCCCCCCCHHHH
RMIEENLREHLRDDEGAVVTVSVPGGERIASRTMNPRLGIIGGISILGTTGIARPMSTEA
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCEEEECHHHHCCCCCCCCCCHHH
YRESLACQIDIATARGFRELVFVPGNIGERFAREYFESIEDERIIQMANFPGYMLEEADG
HHHCCEEEEEEHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCC
RGVERIILMGHAGKLIKLSAGIFQTRSSDADARREIMAAHAALMGASRDTVTRIFNDGTV
CCEEEEEEEECCCCEEEEECCHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCH
EEMISELEGEGLTGRVFNSIADAIRERFNERFSFDTDVLIFSLDGRILNSNFKTKRNHRF
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCCC
TEVF
CCCC
>Mature Secondary Structure
MNDERVFGITTGTAATAAALASLLCLKGCEASKVRVRTPSGILEVDVEYVERISGDTARA
CCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEHHHHHHHCCCCEEE
CVIKRPYPDPDVTVNLEIISTVQITGTPEIMIRGGEGVGIVTKPGLQVPPGEAAINPVPR
EEEECCCCCCCCEEEEEEEEEEEEECCCEEEEECCCCEEEEECCCCCCCCCCCCCCHHHH
RMIEENLREHLRDDEGAVVTVSVPGGERIASRTMNPRLGIIGGISILGTTGIARPMSTEA
HHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCEEEECHHHHCCCCCCCCCCHHH
YRESLACQIDIATARGFRELVFVPGNIGERFAREYFESIEDERIIQMANFPGYMLEEADG
HHHCCEEEEEEHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCC
RGVERIILMGHAGKLIKLSAGIFQTRSSDADARREIMAAHAALMGASRDTVTRIFNDGTV
CCEEEEEEEECCCCEEEEECCHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCH
EEMISELEGEGLTGRVFNSIADAIRERFNERFSFDTDVLIFSLDGRILNSNFKTKRNHRF
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCCCC
TEVF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463