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Identifier: 15678731

GI number: 15678731

Start: 625461

End: 626507

Strand: Direct

Name: Not Available

Synonym: MTH704

Alternate gene names: 15678731

Gene position: 625461-626507 (Clockwise)

Preceding gene: 15678730

Following gene: 15678732

Centisome position: 35.71

GC content: 53.1

Gene sequence:

>1047_bases
ATGGTTAAGGGAAACACTGCGGTGATAATAGGGGCAATGTATGCTGGCTGCGACTGCTACTTCGGCTACCCCATAACACC
GGCAAGTGAGATACTCCATGAGGCTTCAAGGTACTTCCCAATGGTGGGAAGGAAATTCGTGCAGGCAGAATCAGAGGAGG
CAGCCATAAACATGGTATACGGTGCAGCCGCAGCAGGGCACAGGGTAATGACAGCATCATCAGGGCCCGGCATAAGTCTG
AAACAGGAGGGGATCTCCTTCCTTGCCGGTGCAGAGCTCCCTGCAGTCATAGTGGATGTGATGAGGGCCGGTCCGGGTCT
CGGAAATATTGGACCGGAGCAGGGAGACTACAACCAGATTGTGAAGGGCGGAGGGCACGGAAACTACCGTAACATGGTAC
TGGCACCCAGCAGCGTCCAGGAGATGTGCGACCTCACAATGGAGGCCTTTGAACTGGCAGATAAGTACAGGAACCCTGTG
GTTGTCCTCACAGATGCCGTGCTCGGTCAGATGGCTGAACCACTGCGCTTCCCGGAGGAGGCAGTTGAGCACAGACCAGA
CACCTCATGGGCTGTCTGCGGTAACAGGGAGACAATGAAAAACCTTGTAACCTCAATATTCCTTGACTTTGATGAGCTTG
AGGAGTTCAACTTCTACCTCCAGGAGAAGTATGCCAGGATAGAGGAGAACGAGGTGAGATACGAGGAGTATCTGGTGGAT
GATGCAGAGATCGTCATGGTGGCCTATGGTATAAGCAGCAGGGTGGCCAGGAGCGCCGTTGAAACTGCGAGGGCAGAGGG
TATAAATGTGGGCCTCCTCAGACCCATAACACTCTTCCCGTTCCCATCAGACAGAATCCGTGAACTTGCAGATGGTGGCT
GCAGGTTCATATCAGTTGAGATGAGCAGCGGACAGATGAGGGAGGATATAAGGATGGCCTCAGGCTGCAGGGACGTTGAA
CTCGTTAACAGGATGGGTGGAAACCTTATAGAACTCAGGGATGTTCTTGAGAAGATCAGAGAAGTTGCGGGGGATTCCAG
TGACTAA

Upstream 100 bases:

>100_bases
CGGGGAGAGGGGTGCAATGGATGCGGAAACTGCTACTACACCTGCCCCGAGATAAACGCCATTGAGGTCCACATAGAGAG
GTGTGAAGATGGCAACACAG

Downstream 100 bases:

>100_bases
GAAGGTGATCAGAAAGCCGGATTCACTCCACGATGTATTTGAGAGGAAGGGTGGAAGCGCACCCACAGCAACACACTACT
GTGCAGGATGCGGGCACGGT

Product: 2-ketoisovalerate ferredoxin reductase

Products: NA

Alternate protein names: VOR; 2-oxoisovalerate ferredoxin reductase subunit beta; 2-oxoisovalerate oxidoreductase beta chain

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYGAAAAGHRVMTASSGPGISL
KQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYNQIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPV
VVLTDAVLGQMAEPLRFPEEAVEHRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQEKYARIEENEVRYEEYLVD
DAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDIRMASGCRDVE
LVNRMGGNLIELRDVLEKIREVAGDSSD

Sequences:

>Translated_348_residues
MVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYGAAAAGHRVMTASSGPGISL
KQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYNQIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPV
VVLTDAVLGQMAEPLRFPEEAVEHRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQEKYARIEENEVRYEEYLVD
DAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDIRMASGCRDVE
LVNRMGGNLIELRDVLEKIREVAGDSSD
>Mature_348_residues
MVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVYGAAAAGHRVMTASSGPGISL
KQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYNQIVKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPV
VVLTDAVLGQMAEPLRFPEEAVEHRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQEKYARIEENEVRYEEYLVD
DAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLFPFPSDRIRELADGGCRFISVEMSSGQMREDIRMASGCRDVE
LVNRMGGNLIELRDVLEKIREVAGDSSD

Specific function: Unknown

COG id: COG0674

COG function: function code C; Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VORB_METTH (O26800)

Other databases:

- EMBL:   AE000666
- PIR:   A69194
- RefSeq:   NP_275847.1
- ProteinModelPortal:   O26800
- STRING:   O26800
- GeneID:   1470665
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH704
- NMPDR:   fig|187420.1.peg.702
- eggNOG:   arNOG05023
- HOGENOM:   HBG399087
- OMA:   YGAACTG
- ProtClustDB:   PRK07119
- BioCyc:   MTHE187420:MTH704-MONOMER
- BRENDA:   1.2.7.7
- InterPro:   IPR002880
- InterPro:   IPR009014
- InterPro:   IPR015941
- Gene3D:   G3DSA:3.40.50.920

Pfam domain/function: PF01855 POR_N; SSF52922 Transketo_C_like

EC number: =1.2.7.7

Molecular weight: Translated: 38197; Mature: 38197

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVY
CCCCCEEEEEEEHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHEE
GAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYNQI
HHHCCCCEEEEECCCCCCCCHHHCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHH
VKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPEE
HCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCHH
AVEHRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQEKYARIEENEVRYEEYLVD
HHHCCCCCCEEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLFPFPSDRIRELADGGCRFISVE
CCEEEEEEECHHHHHHHHHHHHHHHCCCCEEEECCEEECCCCHHHHHHHHCCCCEEEEEE
MSSGQMREDIRMASGCRDVELVNRMGGNLIELRDVLEKIREVAGDSSD
CCCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVKGNTAVIIGAMYAGCDCYFGYPITPASEILHEASRYFPMVGRKFVQAESEEAAINMVY
CCCCCEEEEEEEHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHEE
GAAAAGHRVMTASSGPGISLKQEGISFLAGAELPAVIVDVMRAGPGLGNIGPEQGDYNQI
HHHCCCCEEEEECCCCCCCCHHHCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHH
VKGGGHGNYRNMVLAPSSVQEMCDLTMEAFELADKYRNPVVVLTDAVLGQMAEPLRFPEE
HCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCHH
AVEHRPDTSWAVCGNRETMKNLVTSIFLDFDELEEFNFYLQEKYARIEENEVRYEEYLVD
HHHCCCCCCEEEECCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DAEIVMVAYGISSRVARSAVETARAEGINVGLLRPITLFPFPSDRIRELADGGCRFISVE
CCEEEEEEECHHHHHHHHHHHHHHHCCCCEEEECCEEECCCCHHHHHHHHCCCCEEEEEE
MSSGQMREDIRMASGCRDVELVNRMGGNLIELRDVLEKIREVAGDSSD
CCCCHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463