Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15678732

GI number: 15678732

Start: 626500

End: 627933

Strand: Direct

Name: Not Available

Synonym: MTH705

Alternate gene names: 15678732

Gene position: 626500-627933 (Clockwise)

Preceding gene: 15678731

Following gene: 15678733

Centisome position: 35.77

GC content: 55.79

Gene sequence:

>1434_bases
GTGACTAAGAAGGTGATCAGAAAGCCGGATTCACTCCACGATGTATTTGAGAGGAAGGGTGGAAGCGCACCCACAGCAAC
ACACTACTGTGCAGGATGCGGGCACGGTATACTGCACAAGCTGATAGGGGAAGCCATGGATGAACTCGGGATACAGGAAA
GGGCCGTCATGATAAGTCCGGTGGGCTGCGCGGTATTCGCCTACTACTACTTTGACTGTGGAAACGTCCAGGTGGCCCAT
GGCCGCGCCCCTGCCGTTGGAACAGGGATATCCCGTGCAGAGGACGACGCGGTTGTCATACTCTACCAGGGCGACGGGGA
CCTTGCATCAATCGGCCTCAACGAGACCATACAGGCAGCCAACCGCGGGGAGAAACTTGCGGTGTTCTTCGTAAACAACA
CCGTCTACGGTATGACCGGAGGCCAGATGGCACCAACAACCCTTGTAGGTGAGGTGACTGTCACCTGCCCCACCGGCAGG
GATCCCAGGTACGCAGGTTACCCCCTCCACATGTGCGAACTTCTGGACAACCTTCAGGCCCCTGTATTCATAGAACGGGT
GTCACTGGCAGACCCCAAGCGGATAAGAAGGGCAAGAAGGGCCATTAAAAGGGCACTGGAGATCCAGAGAGATGGTAAAG
GATACGCATTCGTTGAGGTACTGTCTCCCTGCCCCACAAATCTCAGACAGGACGCTGAAGGTGCAGAAAGGTTCCTCAAG
GAGGAGATGGAGAAGGAATTCCCTGTAAAGAACTTCAGGGACCGTTCAGCCGAAACAGAGCCGCTGATAAGGTCAGAGAG
TGACTTCTCTAGGGAGAGTCTTGACAGGATATTCCAGATCAGGGAGGACTCCGTCCCGGACCCTGTGGATGACCCTGAAT
TCCCTGAGGTGAGGGTGAAGATTGCAGGTTTCGGTGGTCAGGGCGTCCTGAGCATGGGACTGACACTCGCCCAGGCAGCC
TGCAGCGAGGGCAGACACACATCCTGGTACCCTGCCTATGGCCCCGAACAGAGGGGGGGCACCTCAAGCTGCGGCGTTGT
TATATCCGGTGAAAGGGTGGGTTCACCTGCAGTTGACACACCCGACGTCCTGGTGGCCCTCAACCAGCCATCACTCGATG
AATTCGCAGATGACGTGGCCGATGGGGGAATCATACTCTATGACTCCACAACAGCCAGCTTCAGTGGTGGTGCCGTGAGG
GCCATGGGTGTGCCCGCCCTTGAGATCGCAAGGAAACATGGAACAGCAAGGGCCGCCAACACGGTCATGCTGGGGGTTAT
GATGGCCCTCGGACTCACAGGCCTTGATGAGGAATCATTCAGGGAGGCCATAAAATTCACCTTCGCAGGTAAGGAAAAGA
TCATAGATATGAACCTGAGGATCCTTGAGGCAGGTGCAGAGTGGGCAAGAGAAAACATTGAGGGGGAATTATAA

Upstream 100 bases:

>100_bases
TCAGGCTGCAGGGACGTTGAACTCGTTAACAGGATGGGTGGAAACCTTATAGAACTCAGGGATGTTCTTGAGAAGATCAG
AGAAGTTGCGGGGGATTCCA

Downstream 100 bases:

>100_bases
TGTCCTACCAGGGAAGAGCAAGGAAATTCCTGGAATCAGCCTCCATAGATGTGGGGGACATGGTGCTGGTTGAGAAACCA
GACGTCACCTATGAGGGCAT

Product: 2-oxoisovalerate oxidoreductase, alpha subunit

Products: NA

Alternate protein names: VOR; 2-oxoisovalerate oxidoreductase alpha chain; 2-oxoisovalerate-ferredoxin oxidoreductase subunit alpha [H]

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MTKKVIRKPDSLHDVFERKGGSAPTATHYCAGCGHGILHKLIGEAMDELGIQERAVMISPVGCAVFAYYYFDCGNVQVAH
GRAPAVGTGISRAEDDAVVILYQGDGDLASIGLNETIQAANRGEKLAVFFVNNTVYGMTGGQMAPTTLVGEVTVTCPTGR
DPRYAGYPLHMCELLDNLQAPVFIERVSLADPKRIRRARRAIKRALEIQRDGKGYAFVEVLSPCPTNLRQDAEGAERFLK
EEMEKEFPVKNFRDRSAETEPLIRSESDFSRESLDRIFQIREDSVPDPVDDPEFPEVRVKIAGFGGQGVLSMGLTLAQAA
CSEGRHTSWYPAYGPEQRGGTSSCGVVISGERVGSPAVDTPDVLVALNQPSLDEFADDVADGGIILYDSTTASFSGGAVR
AMGVPALEIARKHGTARAANTVMLGVMMALGLTGLDEESFREAIKFTFAGKEKIIDMNLRILEAGAEWARENIEGEL

Sequences:

>Translated_477_residues
MTKKVIRKPDSLHDVFERKGGSAPTATHYCAGCGHGILHKLIGEAMDELGIQERAVMISPVGCAVFAYYYFDCGNVQVAH
GRAPAVGTGISRAEDDAVVILYQGDGDLASIGLNETIQAANRGEKLAVFFVNNTVYGMTGGQMAPTTLVGEVTVTCPTGR
DPRYAGYPLHMCELLDNLQAPVFIERVSLADPKRIRRARRAIKRALEIQRDGKGYAFVEVLSPCPTNLRQDAEGAERFLK
EEMEKEFPVKNFRDRSAETEPLIRSESDFSRESLDRIFQIREDSVPDPVDDPEFPEVRVKIAGFGGQGVLSMGLTLAQAA
CSEGRHTSWYPAYGPEQRGGTSSCGVVISGERVGSPAVDTPDVLVALNQPSLDEFADDVADGGIILYDSTTASFSGGAVR
AMGVPALEIARKHGTARAANTVMLGVMMALGLTGLDEESFREAIKFTFAGKEKIIDMNLRILEAGAEWARENIEGEL
>Mature_476_residues
TKKVIRKPDSLHDVFERKGGSAPTATHYCAGCGHGILHKLIGEAMDELGIQERAVMISPVGCAVFAYYYFDCGNVQVAHG
RAPAVGTGISRAEDDAVVILYQGDGDLASIGLNETIQAANRGEKLAVFFVNNTVYGMTGGQMAPTTLVGEVTVTCPTGRD
PRYAGYPLHMCELLDNLQAPVFIERVSLADPKRIRRARRAIKRALEIQRDGKGYAFVEVLSPCPTNLRQDAEGAERFLKE
EMEKEFPVKNFRDRSAETEPLIRSESDFSRESLDRIFQIREDSVPDPVDDPEFPEVRVKIAGFGGQGVLSMGLTLAQAAC
SEGRHTSWYPAYGPEQRGGTSSCGVVISGERVGSPAVDTPDVLVALNQPSLDEFADDVADGGIILYDSTTASFSGGAVRA
MGVPALEIARKHGTARAANTVMLGVMMALGLTGLDEESFREAIKFTFAGKEKIIDMNLRILEAGAEWARENIEGEL

Specific function: Unknown

COG id: COG1013

COG function: function code C; Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019752
- InterPro:   IPR002869
- InterPro:   IPR011766 [H]

Pfam domain/function: PF01558 POR; PF02775 TPP_enzyme_C [H]

EC number: NA

Molecular weight: Translated: 51628; Mature: 51497

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKVIRKPDSLHDVFERKGGSAPTATHYCAGCGHGILHKLIGEAMDELGIQERAVMISP
CCCHHHCCCHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEC
VGCAVFAYYYFDCGNVQVAHGRAPAVGTGISRAEDDAVVILYQGDGDLASIGLNETIQAA
HHHHHHHHHEEECCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCHHHHHC
NRGEKLAVFFVNNTVYGMTGGQMAPTTLVGEVTVTCPTGRDPRYAGYPLHMCELLDNLQA
CCCCEEEEEEECCEEEECCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCC
PVFIERVSLADPKRIRRARRAIKRALEIQRDGKGYAFVEVLSPCPTNLRQDAEGAERFLK
CEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
EEMEKEFPVKNFRDRSAETEPLIRSESDFSRESLDRIFQIREDSVPDPVDDPEFPEVRVK
HHHHHHCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
IAGFGGQGVLSMGLTLAQAACSEGRHTSWYPAYGPEQRGGTSSCGVVISGERVGSPAVDT
EEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
PDVLVALNQPSLDEFADDVADGGIILYDSTTASFSGGAVRAMGVPALEIARKHGTARAAN
CCEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCHHHHHHHCCCHHHHH
TVMLGVMMALGLTGLDEESFREAIKFTFAGKEKIIDMNLRILEAGAEWARENIEGEL
HHHHHHHHHHCCCCCCHHHHHHHHHEEECCCCEEEECCEEEEECCHHHHHHCCCCCC
>Mature Secondary Structure 
TKKVIRKPDSLHDVFERKGGSAPTATHYCAGCGHGILHKLIGEAMDELGIQERAVMISP
CCHHHCCCHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEC
VGCAVFAYYYFDCGNVQVAHGRAPAVGTGISRAEDDAVVILYQGDGDLASIGLNETIQAA
HHHHHHHHHEEECCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCEEECCCCHHHHHC
NRGEKLAVFFVNNTVYGMTGGQMAPTTLVGEVTVTCPTGRDPRYAGYPLHMCELLDNLQA
CCCCEEEEEEECCEEEECCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCC
PVFIERVSLADPKRIRRARRAIKRALEIQRDGKGYAFVEVLSPCPTNLRQDAEGAERFLK
CEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
EEMEKEFPVKNFRDRSAETEPLIRSESDFSRESLDRIFQIREDSVPDPVDDPEFPEVRVK
HHHHHHCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
IAGFGGQGVLSMGLTLAQAACSEGRHTSWYPAYGPEQRGGTSSCGVVISGERVGSPAVDT
EEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCC
PDVLVALNQPSLDEFADDVADGGIILYDSTTASFSGGAVRAMGVPALEIARKHGTARAAN
CCEEEEECCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEEECCCCHHHHHHHCCCHHHHH
TVMLGVMMALGLTGLDEESFREAIKFTFAGKEKIIDMNLRILEAGAEWARENIEGEL
HHHHHHHHHHCCCCCCHHHHHHHHHEEECCCCEEEECCEEEEECCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9108258 [H]