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Identifier: 15678632

GI number: 15678632

Start: 540313

End: 541200

Strand: Direct

Name: Not Available

Synonym: MTH604

Alternate gene names: 15678632

Gene position: 540313-541200 (Clockwise)

Preceding gene: 15678630

Following gene: 15678633

Centisome position: 30.85

GC content: 51.69

Gene sequence:

>888_bases
ATGGAGAGGTGGAAGCCAGGTCTAATTGCAGTCATAACCGTCGTATCGGTGGCCGCCATGTACCTCATAACATCCACAAC
ATCACCCTGGAGCAGTGGAGATAACATTACAGTCGCTGTGACCATAATGCCCCAGAAGGAATTCGTGGAGGCCATCGCCG
GTGACCGTGCAGAGGTGGTTGTCCTAGTACCCGAGGGGGCCGACCCACACACCTATGAGCCAGAACCAGAAACCCTCAGG
AAGGTTTCAGAGGCCAGGGCCTACTTCATAGTGGGATCAGGAATCGAGTTCGAAAACCACTACCTCAACAAGATAAGGAG
CATGAACCCCCGGATGAGGATAATAAACACCTCAAGGGGTATAGAATTAATCCCAAACCAGGGAGAAGACCATCATCCAG
CCGAAAGCCCCTATGACCCCCACGTATGGACATCCCCAGGAAACGCCATGATAATGGTTAACAACACCATGAGGGGCCTG
CAGGAAATCGACCCCACCGGCAGCAGATACTACCAGGAAAACGCAGGCCTCTACACTGAAAAGCTCATGGACCTCGACTT
CAGGATCAGGAAGGCCCTTGAAAAAAGGAGAGGAGAGAGCATGCTGGTTTACCATCCAGCATGGGGTTACTTCTGCAGGC
AATACGGATTAAAACAGGTGGCGATTGAAAGAGAGGGGAAGGAACCAGGGCCAGGAACACTCTCCATGATAATCCAGGAT
GCCAGAGAAGGTGGTGTGAGGGTCATAATGGTATCACCCCAGTTCAGCAGAAAGAACGCCGAGCTTATAGCCCGTGAAAT
AGGTGCAGAGGTCGTTGTGGTGGACCCCCTTGGTGGAAACTACACGAAAAATATTGAAGCAATAGCAGAGGCTCTGAGGA
GGAAATGA

Upstream 100 bases:

>100_bases
ATAAATGTTTATATATTTTATGTTAAAATTTATTAAATTTTATCGTTTATATTAACAATTATTATATGGTTGCGTTGACA
TAACTTAACAGGGTGGTTGG

Downstream 100 bases:

>100_bases
ACATGCTCGCCATTGAAATGGAGGATTTAAGCTACTGCATCAATGGTAGGGAGATACTCAGGAACATAAACCTGAAGGTG
CCCATGGGGGAACTCCTTGC

Product: adhesion protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MERWKPGLIAVITVVSVAAMYLITSTTSPWSSGDNITVAVTIMPQKEFVEAIAGDRAEVVVLVPEGADPHTYEPEPETLR
KVSEARAYFIVGSGIEFENHYLNKIRSMNPRMRIINTSRGIELIPNQGEDHHPAESPYDPHVWTSPGNAMIMVNNTMRGL
QEIDPTGSRYYQENAGLYTEKLMDLDFRIRKALEKRRGESMLVYHPAWGYFCRQYGLKQVAIEREGKEPGPGTLSMIIQD
AREGGVRVIMVSPQFSRKNAELIAREIGAEVVVVDPLGGNYTKNIEAIAEALRRK

Sequences:

>Translated_295_residues
MERWKPGLIAVITVVSVAAMYLITSTTSPWSSGDNITVAVTIMPQKEFVEAIAGDRAEVVVLVPEGADPHTYEPEPETLR
KVSEARAYFIVGSGIEFENHYLNKIRSMNPRMRIINTSRGIELIPNQGEDHHPAESPYDPHVWTSPGNAMIMVNNTMRGL
QEIDPTGSRYYQENAGLYTEKLMDLDFRIRKALEKRRGESMLVYHPAWGYFCRQYGLKQVAIEREGKEPGPGTLSMIIQD
AREGGVRVIMVSPQFSRKNAELIAREIGAEVVVVDPLGGNYTKNIEAIAEALRRK
>Mature_295_residues
MERWKPGLIAVITVVSVAAMYLITSTTSPWSSGDNITVAVTIMPQKEFVEAIAGDRAEVVVLVPEGADPHTYEPEPETLR
KVSEARAYFIVGSGIEFENHYLNKIRSMNPRMRIINTSRGIELIPNQGEDHHPAESPYDPHVWTSPGNAMIMVNNTMRGL
QEIDPTGSRYYQENAGLYTEKLMDLDFRIRKALEKRRGESMLVYHPAWGYFCRQYGLKQVAIEREGKEPGPGTLSMIIQD
AREGGVRVIMVSPQFSRKNAELIAREIGAEVVVVDPLGGNYTKNIEAIAEALRRK

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=279, Percent_Identity=23.6559139784946, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 33074; Mature: 33074

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERWKPGLIAVITVVSVAAMYLITSTTSPWSSGDNITVAVTIMPQKEFVEAIAGDRAEVV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCCEEE
VLVPEGADPHTYEPEPETLRKVSEARAYFIVGSGIEFENHYLNKIRSMNPRMRIINTSRG
EEEECCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCC
IELIPNQGEDHHPAESPYDPHVWTSPGNAMIMVNNTMRGLQEIDPTGSRYYQENAGLYTE
EEECCCCCCCCCCCCCCCCCCCEECCCCEEEEECCHHHHHHHCCCCCCHHHHHCCCHHHH
KLMDLDFRIRKALEKRRGESMLVYHPAWGYFCRQYGLKQVAIEREGKEPGPGTLSMIIQD
HHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHH
AREGGVRVIMVSPQFSRKNAELIAREIGAEVVVVDPLGGNYTKNIEAIAEALRRK
HHCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MERWKPGLIAVITVVSVAAMYLITSTTSPWSSGDNITVAVTIMPQKEFVEAIAGDRAEVV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCHHHHHHHHCCCCCEEE
VLVPEGADPHTYEPEPETLRKVSEARAYFIVGSGIEFENHYLNKIRSMNPRMRIINTSRG
EEEECCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCC
IELIPNQGEDHHPAESPYDPHVWTSPGNAMIMVNNTMRGLQEIDPTGSRYYQENAGLYTE
EEECCCCCCCCCCCCCCCCCCCEECCCCEEEEECCHHHHHHHCCCCCCHHHHHCCCHHHH
KLMDLDFRIRKALEKRRGESMLVYHPAWGYFCRQYGLKQVAIEREGKEPGPGTLSMIIQD
HHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHH
AREGGVRVIMVSPQFSRKNAELIAREIGAEVVVVDPLGGNYTKNIEAIAEALRRK
HHCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9811636 [H]