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Identifier: 15678502

GI number: 15678502

Start: 415745

End: 415978

Strand: Direct

Name: Not Available

Synonym: MTH474

Alternate gene names: 15678502

Gene position: 415745-415978 (Clockwise)

Preceding gene: 15678501

Following gene: 15678503

Centisome position: 23.74

GC content: 52.56

Gene sequence:

>234_bases
ATGAAGGAATTCCATGACATCTCAGGATGCCCACCGGCATACCTCCCGGCTAAGACCAATGACACGATGGAGATCCTTGA
GGTCCTGGTGGCAGCAGAGAGGTGTGCTGTCAGACAGTGCACCCATATATGTAACATCACCGCCGGGAAGGACCACAGGA
CCTATGACCTTGCACTCTCAATACTCCATGAGGAGATAGCAGCACGAATCATGGTTCTCAGAGTTCCTGGGTGA

Upstream 100 bases:

>100_bases
GCTCAAGGAGATCGCCGAGGCTGCAAGGATAGAGGACAGGAACCACTTCGAGGCCCTTGTACCCAGGATATATGAACTCG
GCGGTGAACTTCCAGGGGAC

Downstream 100 bases:

>100_bases
GGGACCATCAGGTCACTTCATGAGGCGCGGTGAGACATCATCCTTCGTGAGGAAGTTCCTGGAATAATCCATGAATTCAG
TGGTTCCATGAGAATATTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 77; Mature: 77

Protein sequence:

>77_residues
MKEFHDISGCPPAYLPAKTNDTMEILEVLVAAERCAVRQCTHICNITAGKDHRTYDLALSILHEEIAARIMVLRVPG

Sequences:

>Translated_77_residues
MKEFHDISGCPPAYLPAKTNDTMEILEVLVAAERCAVRQCTHICNITAGKDHRTYDLALSILHEEIAARIMVLRVPG
>Mature_77_residues
MKEFHDISGCPPAYLPAKTNDTMEILEVLVAAERCAVRQCTHICNITAGKDHRTYDLALSILHEEIAARIMVLRVPG

Specific function: Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. In vi

COG id: COG2406

COG function: function code R; Protein distantly related to bacterial ferritins

Gene ontology:

Cell location: Cytoplasm, nucleoid [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dps family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012347
- InterPro:   IPR009078
- InterPro:   IPR008331
- InterPro:   IPR014490 [H]

Pfam domain/function: PF00210 Ferritin [H]

EC number: NA

Molecular weight: Translated: 8562; Mature: 8562

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEFHDISGCPPAYLPAKTNDTMEILEVLVAAERCAVRQCTHICNITAGKDHRTYDLALS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ILHEEIAARIMVLRVPG
HHHHHHHHHEEEEECCC
>Mature Secondary Structure
MKEFHDISGCPPAYLPAKTNDTMEILEVLVAAERCAVRQCTHICNITAGKDHRTYDLALS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ILHEEIAARIMVLRVPG
HHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8899719; 11427726 [H]