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Identifier: 15678478

GI number: 15678478

Start: 387429

End: 388664

Strand: Direct

Name: Not Available

Synonym: MTH450

Alternate gene names: 15678478

Gene position: 387429-388664 (Clockwise)

Preceding gene: 15678477

Following gene: 15678479

Centisome position: 22.12

GC content: 47.65

Gene sequence:

>1236_bases
ATTGACCTTAATCATGTTCTGTCCACGCTTCGAGGTCCATGCTATCTCCCCTACCTCGGAAGGTTTAACTGCCTCTTAAC
CATATTAAACACTGGATTCTGTTACCACAGATTATTCAGCTCTATCACAAAGAGAGGTGTTATTTTGGTGCAGGGAGTTC
TTGTGATATCAAACATGTATCCCAGCAGAAAGGGTAAATCATTTGGTAGTTTCGTTAAGGTCCATGTAGATGCATTCAGA
CGTCATACATCCATCAAACAGTTTGTGGTTGCAAACACTGACCAGAGAAAGGGTCTTCCAGTACTCATCAGAAAATACGG
GTCCCTGCTCCTCAGGTCCCTCTGGTATTCCATAAGGAAACCCTTTGATGTCATCCATGCTCACTATCTATTCCCCACAG
GATTCATAGGCCTGCTGTGTCACTGGATAAGTGGCAAACCCCTTGTAGTGACGGTCCATGGCAGTGACGTTAATAAACTT
GCAAGGAAGAATTCCCTTCTCTCTAAAATTTCAGGCTTCATCCTCAGAAGGACCTCTGCAGTCATCGCTGTCAGCAGAGA
CCTTGGGGAGAAGGTCGTGAATGAATTCGGGGTCGACAGGGGGAAGGTGCATGTCATCAACATGGGTGTTGACACAGATA
TCTTCATGCCACTTGATAGGGATGAATGTCGTGAAAGACTAGGATTACCCCTAAAGGGAAGGGTGGTCCTCTTTGTTGGG
AACATCATACCCTCAAAGGGAGTGTATTACCTCATCGAATCCCTCAAGGACTTAGAGCTCGATGATGTTAAATGCATAAT
ACTTGGAGCCCCCGTTGATGAGGAGTACCTCAGAACCCTCAGGGGGCTGGCTGAATCCATGGATTCCGATGTGGAATTTT
TTGGACCTGTACCGTACACTGAGGTGCCAACCTGGATGAATGCCGCAGATGTCTTTGTTCTACCATCCCTTGAGGAGGGT
TTTGGGCTTGTTGCACTTGAAGCACTCGCCTGCGGCACCCCTGTCATTGCAACTGCCACAGGCGGCATTATGGAATTTGT
CAGGGACTCAGAAACAGGATACACCGTGCCCCCAGGGGATTCCCGTGCCATTGCTGACAGGATAAAGAGGATACTTGATC
CCGAAAACCGGGCTGAGGTTGAGTCCATGAGGGAAAGGGGTATGCGGCTTGCTGAGTCATTCAGTACCATTAAACAGATA
GAAAAGGTACTTGAGGTCTACCGTCAGGTTTCATGA

Upstream 100 bases:

>100_bases
CTGTACAGTTGAATACCTCAGGTCCGCAATTGAGGATGCTAAAATCGATAAAAAAGAACGTCTAAGGGCTTTGAAGTCTC
TTAATAGTTTTTTGAGGTAG

Downstream 100 bases:

>100_bases
ACTGAAATGGTTATATACAGGACAGACCCCTTTATTATTACTTTTAATACAGTCAGGTACATATTAGTAATACTCATCTT
TTTTTAGAAATTATTAAATA

Product: LPS biosynthesis RfbU related protein

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MDLNHVLSTLRGPCYLPYLGRFNCLLTILNTGFCYHRLFSSITKRGVILVQGVLVISNMYPSRKGKSFGSFVKVHVDAFR
RHTSIKQFVVANTDQRKGLPVLIRKYGSLLLRSLWYSIRKPFDVIHAHYLFPTGFIGLLCHWISGKPLVVTVHGSDVNKL
ARKNSLLSKISGFILRRTSAVIAVSRDLGEKVVNEFGVDRGKVHVINMGVDTDIFMPLDRDECRERLGLPLKGRVVLFVG
NIIPSKGVYYLIESLKDLELDDVKCIILGAPVDEEYLRTLRGLAESMDSDVEFFGPVPYTEVPTWMNAADVFVLPSLEEG
FGLVALEALACGTPVIATATGGIMEFVRDSETGYTVPPGDSRAIADRIKRILDPENRAEVESMRERGMRLAESFSTIKQI
EKVLEVYRQVS

Sequences:

>Translated_411_residues
MDLNHVLSTLRGPCYLPYLGRFNCLLTILNTGFCYHRLFSSITKRGVILVQGVLVISNMYPSRKGKSFGSFVKVHVDAFR
RHTSIKQFVVANTDQRKGLPVLIRKYGSLLLRSLWYSIRKPFDVIHAHYLFPTGFIGLLCHWISGKPLVVTVHGSDVNKL
ARKNSLLSKISGFILRRTSAVIAVSRDLGEKVVNEFGVDRGKVHVINMGVDTDIFMPLDRDECRERLGLPLKGRVVLFVG
NIIPSKGVYYLIESLKDLELDDVKCIILGAPVDEEYLRTLRGLAESMDSDVEFFGPVPYTEVPTWMNAADVFVLPSLEEG
FGLVALEALACGTPVIATATGGIMEFVRDSETGYTVPPGDSRAIADRIKRILDPENRAEVESMRERGMRLAESFSTIKQI
EKVLEVYRQVS
>Mature_411_residues
MDLNHVLSTLRGPCYLPYLGRFNCLLTILNTGFCYHRLFSSITKRGVILVQGVLVISNMYPSRKGKSFGSFVKVHVDAFR
RHTSIKQFVVANTDQRKGLPVLIRKYGSLLLRSLWYSIRKPFDVIHAHYLFPTGFIGLLCHWISGKPLVVTVHGSDVNKL
ARKNSLLSKISGFILRRTSAVIAVSRDLGEKVVNEFGVDRGKVHVINMGVDTDIFMPLDRDECRERLGLPLKGRVVLFVG
NIIPSKGVYYLIESLKDLELDDVKCIILGAPVDEEYLRTLRGLAESMDSDVEFFGPVPYTEVPTWMNAADVFVLPSLEEG
FGLVALEALACGTPVIATATGGIMEFVRDSETGYTVPPGDSRAIADRIKRILDPENRAEVESMRERGMRLAESFSTIKQI
EKVLEVYRQVS

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788357, Length=275, Percent_Identity=29.0909090909091, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 45985; Mature: 45985

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNHVLSTLRGPCYLPYLGRFNCLLTILNTGFCYHRLFSSITKRGVILVQGVLVISNMY
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCC
PSRKGKSFGSFVKVHVDAFRRHTSIKQFVVANTDQRKGLPVLIRKYGSLLLRSLWYSIRK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC
PFDVIHAHYLFPTGFIGLLCHWISGKPLVVTVHGSDVNKLARKNSLLSKISGFILRRTSA
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VIAVSRDLGEKVVNEFGVDRGKVHVINMGVDTDIFMPLDRDECRERLGLPLKGRVVLFVG
HEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCHHHHHHHHCCCCCCEEEEEEE
NIIPSKGVYYLIESLKDLELDDVKCIILGAPVDEEYLRTLRGLAESMDSDVEFFGPVPYT
CCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCC
EVPTWMNAADVFVLPSLEEGFGLVALEALACGTPVIATATGGIMEFVRDSETGYTVPPGD
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCEEECCCHHHHHHHHCCCCCCCCCCCC
SRAIADRIKRILDPENRAEVESMRERGMRLAESFSTIKQIEKVLEVYRQVS
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLNHVLSTLRGPCYLPYLGRFNCLLTILNTGFCYHRLFSSITKRGVILVQGVLVISNMY
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCC
PSRKGKSFGSFVKVHVDAFRRHTSIKQFVVANTDQRKGLPVLIRKYGSLLLRSLWYSIRK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHC
PFDVIHAHYLFPTGFIGLLCHWISGKPLVVTVHGSDVNKLARKNSLLSKISGFILRRTSA
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
VIAVSRDLGEKVVNEFGVDRGKVHVINMGVDTDIFMPLDRDECRERLGLPLKGRVVLFVG
HEEEHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCHHHHHHHHCCCCCCEEEEEEE
NIIPSKGVYYLIESLKDLELDDVKCIILGAPVDEEYLRTLRGLAESMDSDVEFFGPVPYT
CCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCC
EVPTWMNAADVFVLPSLEEGFGLVALEALACGTPVIATATGGIMEFVRDSETGYTVPPGD
CCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCCEEECCCHHHHHHHHCCCCCCCCCCCC
SRAIADRIKRILDPENRAEVESMRERGMRLAESFSTIKQIEKVLEVYRQVS
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA