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Identifier: 15678292

GI number: 15678292

Start: 203849

End: 204403

Strand: Direct

Name: Not Available

Synonym: MTH264

Alternate gene names: 15678292

Gene position: 203849-204403 (Clockwise)

Preceding gene: 15678291

Following gene: 15678293

Centisome position: 11.64

GC content: 51.35

Gene sequence:

>555_bases
TTGTATTATGTAACAAAGATTGTTGATACCGTCAGAATACCTCCAGACCGCTTTGAAGAGCCACTGGAGGAGGTCGCCGT
CGAGGTTCTAAACGAGACCTACGTTGGAAGGATGGATAAGAACCTCGGGCAGCTGATAACCGTCAAAGAGATAGAGGATA
TAGGGATAGGAAAGGTTATAATGGGTGACGGTGCCGCCTACCATGAGGTGACCTTCACAGCCCTCTTCTTCAAACCTGAA
CTACATGAAATCGTTGAGGGTGAGGTTATAGAGATAGCAGAGTTCGGAGCCTTCGTGCGCATAGGTCCGGTGGATGGCCT
GGTGCACGTTTCACAGGTAACCGACGACTACATAACCTACGACCCCAAGAAGGGCTCCCTCACAGGTAAGGAGTCAGGCA
GACGCCTCGACGAGGGCGACCTTGTAAGGGCAAGGATAGTCGCACTCAGCCTCAAGGGCCGAAGAGAGGGCGTAAAGGTG
GGCCTCACCATGAGGCAGCCCGGCCTTGGAAAATTCGAATGGATTGAAGAAGAGAAGAGGAAGAGTAAAAAATGA

Upstream 100 bases:

>100_bases
TCGGATGGGAGGGTGCTGAAAAGGCATTTGAAGCAGTCAACCACTCCATAGAACTCTACAGGAAAAAATATATGGAGTAA
TTCTTTAATGGGGGATCCCA

Downstream 100 bases:

>100_bases
CTGAGAAGGCATGCACAAGGTGTAAGAGAATCACCAGTGACGAAAGATGCCCGGTCTGCAATGTCCCGGCATCCACCAAC
TGGAGCGGACTCCTCATAAT

Product: DNA-directed RNA polymerase subunit E'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MYYVTKIVDTVRIPPDRFEEPLEEVAVEVLNETYVGRMDKNLGQLITVKEIEDIGIGKVIMGDGAAYHEVTFTALFFKPE
LHEIVEGEVIEIAEFGAFVRIGPVDGLVHVSQVTDDYITYDPKKGSLTGKESGRRLDEGDLVRARIVALSLKGRREGVKV
GLTMRQPGLGKFEWIEEEKRKSKK

Sequences:

>Translated_184_residues
MYYVTKIVDTVRIPPDRFEEPLEEVAVEVLNETYVGRMDKNLGQLITVKEIEDIGIGKVIMGDGAAYHEVTFTALFFKPE
LHEIVEGEVIEIAEFGAFVRIGPVDGLVHVSQVTDDYITYDPKKGSLTGKESGRRLDEGDLVRARIVALSLKGRREGVKV
GLTMRQPGLGKFEWIEEEKRKSKK
>Mature_184_residues
MYYVTKIVDTVRIPPDRFEEPLEEVAVEVLNETYVGRMDKNLGQLITVKEIEDIGIGKVIMGDGAAYHEVTFTALFFKPE
LHEIVEGEVIEIAEFGAFVRIGPVDGLVHVSQVTDDYITYDPKKGSLTGKESGRRLDEGDLVRARIVALSLKGRREGVKV
GLTMRQPGLGKFEWIEEEKRKSKK

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG1095

COG function: function code K; DNA-directed RNA polymerase, subunit E'

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI24475814, Length=108, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=8e-11,
Organism=Homo sapiens, GI65301161, Length=108, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322705, Length=150, Percent_Identity=30, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR005576
- InterPro:   IPR004519 [H]

Pfam domain/function: PF03876 RNA_pol_Rpb7_N; PF00575 S1 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 20695; Mature: 20695

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYVTKIVDTVRIPPDRFEEPLEEVAVEVLNETYVGRMDKNLGQLITVKEIEDIGIGKVI
CEEHHEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEE
MGDGAAYHEVTFTALFFKPELHEIVEGEVIEIAEFGAFVRIGPVDGLVHVSQVTDDYITY
ECCCCCCHHEEEEEEEECCHHHHHHCCCEEEEECCCCEEEECCCCCEEEHHHCCCCCEEE
DPKKGSLTGKESGRRLDEGDLVRARIVALSLKGRREGVKVGLTMRQPGLGKFEWIEEEKR
CCCCCCCCCCCCCCCCCCCCHHEEEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHH
KSKK
HCCC
>Mature Secondary Structure
MYYVTKIVDTVRIPPDRFEEPLEEVAVEVLNETYVGRMDKNLGQLITVKEIEDIGIGKVI
CEEHHEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEE
MGDGAAYHEVTFTALFFKPELHEIVEGEVIEIAEFGAFVRIGPVDGLVHVSQVTDDYITY
ECCCCCCHHEEEEEEEECCHHHHHHCCCEEEEECCCCEEEECCCCCEEEHHHCCCCCEEE
DPKKGSLTGKESGRRLDEGDLVRARIVALSLKGRREGVKVGLTMRQPGLGKFEWIEEEKR
CCCCCCCCCCCCCCCCCCCCHHEEEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHH
KSKK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]