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Identifier: 15678074

GI number: 15678074

Start: 23574

End: 24407

Strand: Direct

Name: Not Available

Synonym: MTH45

Alternate gene names: NA

Gene position: 23574-24407 (Clockwise)

Preceding gene: 15678073

Following gene: 15678075

Centisome position: 1.35

GC content: 55.4

Gene sequence:

>834_bases
ATGATAAGGAGACCTGCAGTGGCGGGAGCTTTCTATGAACGGGACCCCGCGGCCCTCAGAAGGCGCATTGAATGGTGTTT
CGAGCATGAGCTCGGACCCGGCACCCTTCCGGCAGTGGGGTCCATGAGGAGGATAAAGGGGGTGATCGCCCCCCACGCAG
GTTACATGTATTCAGGACCCGTGGCAGCACACGCCTACCATGAGCTGGTATCCGATGGAATCCCCGGGACCCTGGTGATA
ATCTGCCCCAACCACACAGGGATGGGGTCAGGTGTATCGCTTATGCAGCAGGGTGCATGGGAGACACCCCTCGGTACAGT
GGAGATAGACTCAGAGCTTGCAGAAGCCATTGTGAGAGAATCAGGGATCATAGACCTGGATGAGACAGCACACCTCGCCG
AGCACAGCTGTGAGGTGCATGTACCCTTCATCCAGTACTTCACAGATAACTTCAGGATAGTTCCAGTTACCATGTGGATG
CAGGGCCATGAGACAGCCGCCGATGTTGGACATGCGGTCGCATCAGCCATCAGGGAAACCGGAAGGGATGCGGCTGTCAT
CGCAAGCACAGACTTCACACACTACAGTCCACAGGACATTGCTGAAGCCACCGACAGAAGGATCATTGACAGGATAACAG
CAATGGATGATACCGGCATGTACGGTGTTATCAGTGAACTCAACGCAACCATGTGCGGTTATGGGCCGGTAGCGGCTACC
ATCATAGCCTCAAGGATTCTTGGAGCCACAGAATGCGACCTACTGAGATATGCAACAAGTGGAGATGTTACCGGTGACCG
CAGCTCGGTGGTGGGCTACGCTCACTTGTCCTGA

Upstream 100 bases:

>100_bases
CTGGCAAGGCAGTTCCTCCGGGAGAAGGGCATCCTCAAGGAGGATGAGGACCTGGACATACCTCCAACAGAGTTCGAACT
GAAGATCTAGAAGTGGTCAT

Downstream 100 bases:

>100_bases
GATAAGGGTGAAACATTGAAGTCGTCGGCATCCGCACCTGCCAAGGCCATTCTTTTTGGTGAACACGCAGTGGTCTACAG
CAAGCCGGCAATAGCAGCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MIRRPAVAGAFYERDPAALRRRIEWCFEHELGPGTLPAVGSMRRIKGVIAPHAGYMYSGPVAAHAYHELVSDGIPGTLVI
ICPNHTGMGSGVSLMQQGAWETPLGTVEIDSELAEAIVRESGIIDLDETAHLAEHSCEVHVPFIQYFTDNFRIVPVTMWM
QGHETAADVGHAVASAIRETGRDAAVIASTDFTHYSPQDIAEATDRRIIDRITAMDDTGMYGVISELNATMCGYGPVAAT
IIASRILGATECDLLRYATSGDVTGDRSSVVGYAHLS

Sequences:

>Translated_277_residues
MIRRPAVAGAFYERDPAALRRRIEWCFEHELGPGTLPAVGSMRRIKGVIAPHAGYMYSGPVAAHAYHELVSDGIPGTLVI
ICPNHTGMGSGVSLMQQGAWETPLGTVEIDSELAEAIVRESGIIDLDETAHLAEHSCEVHVPFIQYFTDNFRIVPVTMWM
QGHETAADVGHAVASAIRETGRDAAVIASTDFTHYSPQDIAEATDRRIIDRITAMDDTGMYGVISELNATMCGYGPVAAT
IIASRILGATECDLLRYATSGDVTGDRSSVVGYAHLS
>Mature_277_residues
MIRRPAVAGAFYERDPAALRRRIEWCFEHELGPGTLPAVGSMRRIKGVIAPHAGYMYSGPVAAHAYHELVSDGIPGTLVI
ICPNHTGMGSGVSLMQQGAWETPLGTVEIDSELAEAIVRESGIIDLDETAHLAEHSCEVHVPFIQYFTDNFRIVPVTMWM
QGHETAADVGHAVASAIRETGRDAAVIASTDFTHYSPQDIAEATDRRIIDRITAMDDTGMYGVISELNATMCGYGPVAAT
IIASRILGATECDLLRYATSGDVTGDRSSVVGYAHLS

Specific function: Unknown

COG id: COG1355

COG function: function code R; Predicted dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0103 family

Homologues:

Organism=Homo sapiens, GI7705720, Length=299, Percent_Identity=26.4214046822742, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25146594, Length=260, Percent_Identity=26.5384615384615, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32566861, Length=260, Percent_Identity=26.5384615384615, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357419, Length=296, Percent_Identity=27.3648648648649, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y045_METTH (O26151)

Other databases:

- EMBL:   AE000666
- PIR:   G69158
- RefSeq:   NP_275188.1
- ProteinModelPortal:   O26151
- SMR:   O26151
- STRING:   O26151
- GeneID:   1470007
- GenomeReviews:   AE000666_GR
- KEGG:   mth:MTH45
- NMPDR:   fig|187420.1.peg.43
- eggNOG:   arNOG05614
- HOGENOM:   HBG575564
- OMA:   GPNHTGY
- PhylomeDB:   O26151
- ProtClustDB:   CLSK213947
- BioCyc:   MTHE187420:MTH45-MONOMER
- HAMAP:   MF_00055
- InterPro:   IPR020619
- InterPro:   IPR002737
- PANTHER:   PTHR11060

Pfam domain/function: PF01875 Memo

EC number: NA

Molecular weight: Translated: 29815; Mature: 29815

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRPAVAGAFYERDPAALRRRIEWCFEHELGPGTLPAVGSMRRIKGVIAPHAGYMYSGP
CCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCC
VAAHAYHELVSDGIPGTLVIICPNHTGMGSGVSLMQQGAWETPLGTVEIDSELAEAIVRE
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHH
SGIIDLDETAHLAEHSCEVHVPFIQYFTDNFRIVPVTMWMQGHETAADVGHAVASAIRET
CCCEECCHHHHHHHCCCEEEEHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHC
GRDAAVIASTDFTHYSPQDIAEATDRRIIDRITAMDDTGMYGVISELNATMCGYGPVAAT
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHCCCHHHHHH
IIASRILGATECDLLRYATSGDVTGDRSSVVGYAHLS
HHHHHHCCCCHHHHHEEECCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MIRRPAVAGAFYERDPAALRRRIEWCFEHELGPGTLPAVGSMRRIKGVIAPHAGYMYSGP
CCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCC
VAAHAYHELVSDGIPGTLVIICPNHTGMGSGVSLMQQGAWETPLGTVEIDSELAEAIVRE
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCCEEEHHHHHHHHHHH
SGIIDLDETAHLAEHSCEVHVPFIQYFTDNFRIVPVTMWMQGHETAADVGHAVASAIRET
CCCEECCHHHHHHHCCCEEEEHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHC
GRDAAVIASTDFTHYSPQDIAEATDRRIIDRITAMDDTGMYGVISELNATMCGYGPVAAT
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHCCCHHHHHH
IIASRILGATECDLLRYATSGDVTGDRSSVVGYAHLS
HHHHHHCCCCHHHHHEEECCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463