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Identifier: 15646114

GI number: 15646114

Start: 1577937

End: 1578971

Strand: Reverse

Name: Not Available

Synonym: HP1505

Alternate gene names: 15646114

Gene position: 1578971-1577937 (Counterclockwise)

Preceding gene: 15646115

Following gene: 15646113

Centisome position: 94.67

GC content: 40.19

Gene sequence:

>1035_bases
ATGAGACTTTATGAGAGTTTATTAGAAATGTGCTTGAATAAGGCATGGGAGCATCAAACCCTAGCCTTAGAAAACCCAAG
CGTAGCTTGCATGGTGTTGGATAAAAACCATGAGATCTTGAGTTTAGAAACCCACAAAAAAGCCAAAACCCCGCATGCAG
AAGTCTTAGCCGCCCAATCAGCGCTAAAGATTTTACGCCCCAGTTTGAAAAACGATTTAGAAAAGTTAGAAGACCCTAAA
ACTTTAAGCGATTTTTTAAAAACGCACCACGATAACGCTTTTACAGACTGCGTTTTTTTAATCACCTTAGAGCCATGCAA
TTCTTATGGCAAAACCCCGGCTTGTAGCGAATTGTTAGAAATTTTAAAGCCTAAAAGAGTGGTCATTGCCACAGAAGAAA
ACGAAGCTAAAAAAGGGGGTTTAGCAAGGCTACAAAAGGCTCGTATTGAAACAATAATTTGCCACAATTTAGAAAACAAA
GCTAAAGACTTGCTCTTGCCTTTTAGGGTAATGGAACAAAAGGGGCGTTTTAATTTGTTCAAACTCGCTTTAAGAATGAA
TGGGGATTACCATCATGGCAAGATCACCGGGCAAAAAAGCGTTATTTTCACGCACAACCAGCGAGCAATATGCGACACGC
TTATTGTTTCTGGGAAAACCATAAGAACGGACAACCCCTTATTGGACGCTCGCTTTTGCGACAGCTTTTATCAAAATAAA
AACCCCAATATCGCTATTTTATCCAAGCGCTCAATTGACCCTAATTCAAAAGTTTTTTCTGCGCCTAATCGTTTAGTTAA
CACTTTCCATGACCCCAAAGATTTACCCCTAGAGAAGGGGTTTAATTTCATTGAAGGGGGGTGGGAATTGTTTGAGAGCT
TGAGGGATAAAATAGACGCGTTGCTTTTGCATTCGCATGCGTCTATGATTGGCGAAGCGTTTAAGGCACTCGCTCTAAAA
ACCCCTTTTAAAGGACGGTTGTTGCATGCGCAAATCTTAGAAAATGAAGCCCTTTTATGGATAGAAAACTCTTAA

Upstream 100 bases:

>100_bases
ATGTGGCGTTTATCGTCGTGCCTTTAGTGGGAGCGTTTTTTGTTGATATTATTAACGCTTTAGCGATTAAAGGCTTTTTG
CTCTTGCCTTTTTTCCCATC

Downstream 100 bases:

>100_bases
GATTATACCAGCCTTTGAACGCTTATTCTTACAACAGCGATTCGCTTTTTTTATACGATTTTTCACGCCCTTTTATCAAA
AACAGCGGCGCGATTTTAGA

Product: riboflavin biosynthesis protein (ribG)

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MRLYESLLEMCLNKAWEHQTLALENPSVACMVLDKNHEILSLETHKKAKTPHAEVLAAQSALKILRPSLKNDLEKLEDPK
TLSDFLKTHHDNAFTDCVFLITLEPCNSYGKTPACSELLEILKPKRVVIATEENEAKKGGLARLQKARIETIICHNLENK
AKDLLLPFRVMEQKGRFNLFKLALRMNGDYHHGKITGQKSVIFTHNQRAICDTLIVSGKTIRTDNPLLDARFCDSFYQNK
NPNIAILSKRSIDPNSKVFSAPNRLVNTFHDPKDLPLEKGFNFIEGGWELFESLRDKIDALLLHSHASMIGEAFKALALK
TPFKGRLLHAQILENEALLWIENS

Sequences:

>Translated_344_residues
MRLYESLLEMCLNKAWEHQTLALENPSVACMVLDKNHEILSLETHKKAKTPHAEVLAAQSALKILRPSLKNDLEKLEDPK
TLSDFLKTHHDNAFTDCVFLITLEPCNSYGKTPACSELLEILKPKRVVIATEENEAKKGGLARLQKARIETIICHNLENK
AKDLLLPFRVMEQKGRFNLFKLALRMNGDYHHGKITGQKSVIFTHNQRAICDTLIVSGKTIRTDNPLLDARFCDSFYQNK
NPNIAILSKRSIDPNSKVFSAPNRLVNTFHDPKDLPLEKGFNFIEGGWELFESLRDKIDALLLHSHASMIGEAFKALALK
TPFKGRLLHAQILENEALLWIENS
>Mature_344_residues
MRLYESLLEMCLNKAWEHQTLALENPSVACMVLDKNHEILSLETHKKAKTPHAEVLAAQSALKILRPSLKNDLEKLEDPK
TLSDFLKTHHDNAFTDCVFLITLEPCNSYGKTPACSELLEILKPKRVVIATEENEAKKGGLARLQKARIETIICHNLENK
AKDLLLPFRVMEQKGRFNLFKLALRMNGDYHHGKITGQKSVIFTHNQRAICDTLIVSGKTIRTDNPLLDARFCDSFYQNK
NPNIAILSKRSIDPNSKVFSAPNRLVNTFHDPKDLPLEKGFNFIEGGWELFESLRDKIDALLLHSHASMIGEAFKALALK
TPFKGRLLHAQILENEALLWIENS

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39026; Mature: 39026

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLYESLLEMCLNKAWEHQTLALENPSVACMVLDKNHEILSLETHKKAKTPHAEVLAAQS
CCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHH
ALKILRPSLKNDLEKLEDPKTLSDFLKTHHDNAFTDCVFLITLEPCNSYGKTPACSELLE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHH
ILKPKRVVIATEENEAKKGGLARLQKARIETIICHNLENKAKDLLLPFRVMEQKGRFNLF
HHCCCEEEEEECCCCCHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEE
KLALRMNGDYHHGKITGQKSVIFTHNQRAICDTLIVSGKTIRTDNPLLDARFCDSFYQNK
EEEEEECCCCCCCEECCCCEEEEECCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCC
NPNIAILSKRSIDPNSKVFSAPNRLVNTFHDPKDLPLEKGFNFIEGGWELFESLRDKIDA
CCCEEEEEECCCCCCCCEECCCHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
LLLHSHASMIGEAFKALALKTPFKGRLLHAQILENEALLWIENS
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEECCCCEEEEEECC
>Mature Secondary Structure
MRLYESLLEMCLNKAWEHQTLALENPSVACMVLDKNHEILSLETHKKAKTPHAEVLAAQS
CCHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHH
ALKILRPSLKNDLEKLEDPKTLSDFLKTHHDNAFTDCVFLITLEPCNSYGKTPACSELLE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHH
ILKPKRVVIATEENEAKKGGLARLQKARIETIICHNLENKAKDLLLPFRVMEQKGRFNLF
HHCCCEEEEEECCCCCHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEE
KLALRMNGDYHHGKITGQKSVIFTHNQRAICDTLIVSGKTIRTDNPLLDARFCDSFYQNK
EEEEEECCCCCCCEECCCCEEEEECCCHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHCC
NPNIAILSKRSIDPNSKVFSAPNRLVNTFHDPKDLPLEKGFNFIEGGWELFESLRDKIDA
CCCEEEEEECCCCCCCCEECCCHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
LLLHSHASMIGEAFKALALKTPFKGRLLHAQILENEALLWIENS
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEHEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]