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Identifier: 15646113

GI number: 15646113

Start: 1577239

End: 1577955

Strand: Reverse

Name: Not Available

Synonym: HP1504

Alternate gene names: 15646113

Gene position: 1577955-1577239 (Counterclockwise)

Preceding gene: 15646114

Following gene: 15646112

Centisome position: 94.61

GC content: 39.61

Gene sequence:

>717_bases
ATGGATAGAAAACTCTTAAGATTATACCAGCCTTTGAACGCTTATTCTTACAACAGCGATTCGCTTTTTTTATACGATTT
TTCACGCCCTTTTATCAAAAACAGCGGCGCGATTTTAGACATAGGCTCAGGGTGTGGGATCTTAGGCTTACTCTGCGCCA
GAGACAACCCGCTAGCGATCGTTCATTTGGTGGAAAAGGATAACAAAATGGCGTTTTGCTCCCAAAAAAACGCCCTTAAA
TTCCCTAACGCTCAAGTGTTTGAGGGCGATTTTTTAGATTTCAATCCCCCGATTTTATATGATATAATTGTGTGCAACCC
TCCTTTTTATGCCTTAGGCTCTATCAAATCTAAAATTAAAGGGCATGCGAGGCACCAGAGCGAATTAGACTTCGCTTCTT
TGGTGGCTAAAGTGAAAAAATGCCTAAAACCTAAAGGGTATTTTATTTTTTGCTATGAAGCCTTGTCGCTTTGCTTGGTC
ATAGAGGGTTTAAAAAGCGTTAAACTCACGCTAGAAACTTTAAGGTTTGTCCAAAGTTTTAAAGACAAAAACGCCCATTT
GATGCTTGGAGCGGCTAGGAATAATTCCAAAAGCGCTCTAAAAGTTTTGCCCCCTTTAATCACGCACCATTCCAAAAACC
AAAGCGACAACACCAAAGAAGTTTTAAGCATCTATCAAACTTGTAACACTTATTCTATCAAAGCGCTTCTAAACTAG

Upstream 100 bases:

>100_bases
ATGCGTCTATGATTGGCGAAGCGTTTAAGGCACTCGCTCTAAAAACCCCTTTTAAAGGACGGTTGTTGCATGCGCAAATC
TTAGAAAATGAAGCCCTTTT

Downstream 100 bases:

>100_bases
CGCCCTTAAATTAAGGATTAAAAAAATGAAATGTTCGCATTGCCAGTTGGAGTTTAAAGAAAGTGAGCTTTTTAAAGAGG
TGATCAATCATAAAGAATTG

Product: hypothetical protein

Products: NA

Alternate protein names: tRNA m6A37 methyltransferase [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MDRKLLRLYQPLNAYSYNSDSLFLYDFSRPFIKNSGAILDIGSGCGILGLLCARDNPLAIVHLVEKDNKMAFCSQKNALK
FPNAQVFEGDFLDFNPPILYDIIVCNPPFYALGSIKSKIKGHARHQSELDFASLVAKVKKCLKPKGYFIFCYEALSLCLV
IEGLKSVKLTLETLRFVQSFKDKNAHLMLGAARNNSKSALKVLPPLITHHSKNQSDNTKEVLSIYQTCNTYSIKALLN

Sequences:

>Translated_238_residues
MDRKLLRLYQPLNAYSYNSDSLFLYDFSRPFIKNSGAILDIGSGCGILGLLCARDNPLAIVHLVEKDNKMAFCSQKNALK
FPNAQVFEGDFLDFNPPILYDIIVCNPPFYALGSIKSKIKGHARHQSELDFASLVAKVKKCLKPKGYFIFCYEALSLCLV
IEGLKSVKLTLETLRFVQSFKDKNAHLMLGAARNNSKSALKVLPPLITHHSKNQSDNTKEVLSIYQTCNTYSIKALLN
>Mature_238_residues
MDRKLLRLYQPLNAYSYNSDSLFLYDFSRPFIKNSGAILDIGSGCGILGLLCARDNPLAIVHLVEKDNKMAFCSQKNALK
FPNAQVFEGDFLDFNPPILYDIIVCNPPFYALGSIKSKIKGHARHQSELDFASLVAKVKKCLKPKGYFIFCYEALSLCLV
IEGLKSVKLTLETLRFVQSFKDKNAHLMLGAARNNSKSALKVLPPLITHHSKNQSDNTKEVLSIYQTCNTYSIKALLN

Specific function: Specifically methylates the adenine in position 37 of tRNA(Val) [H]

COG id: COG4123

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR020596
- InterPro:   IPR007848
- InterPro:   IPR022882 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.55 [H]

Molecular weight: Translated: 26688; Mature: 26688

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRKLLRLYQPLNAYSYNSDSLFLYDFSRPFIKNSGAILDIGSGCGILGLLCARDNPLAI
CCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCEEEECCCCCEEE
VHLVEKDNKMAFCSQKNALKFPNAQVFEGDFLDFNPPILYDIIVCNPPFYALGSIKSKIK
EEEEECCCCEEEECCCCCCCCCCCEEECCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHH
GHARHQSELDFASLVAKVKKCLKPKGYFIFCYEALSLCLVIEGLKSVKLTLETLRFVQSF
HHHCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDKNAHLMLGAARNNSKSALKVLPPLITHHSKNQSDNTKEVLSIYQTCNTYSIKALLN
CCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure
MDRKLLRLYQPLNAYSYNSDSLFLYDFSRPFIKNSGAILDIGSGCGILGLLCARDNPLAI
CCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCEEEECCCCCEEE
VHLVEKDNKMAFCSQKNALKFPNAQVFEGDFLDFNPPILYDIIVCNPPFYALGSIKSKIK
EEEEECCCCEEEECCCCCCCCCCCEEECCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHH
GHARHQSELDFASLVAKVKKCLKPKGYFIFCYEALSLCLVIEGLKSVKLTLETLRFVQSF
HHHCCCCCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDKNAHLMLGAARNNSKSALKVLPPLITHHSKNQSDNTKEVLSIYQTCNTYSIKALLN
CCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA