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The map label for this gene is coaD

Identifier: 15646084

GI number: 15646084

Start: 1547912

End: 1548385

Strand: Reverse

Name: coaD

Synonym: HP1475

Alternate gene names: 15646084

Gene position: 1548385-1547912 (Counterclockwise)

Preceding gene: 15646085

Following gene: 15646083

Centisome position: 92.84

GC content: 40.93

Gene sequence:

>474_bases
ATGCAAAAAATCGGCATTTACCCGGGCACTTTTGATCCGGTCACTAACGGGCATATAGACATTATCCACCGATCCAGCGA
ATTGTTTGAAAAGCTCATTGTCGCTGTGGCACATTCAAGCGCTAAAAACCCTATGTTTAGTTTAGATGAGCGCTTAAAAA
TGATACAACTCGCCACTAAAAGTTTTAAAAATGTAGAATGCGTGGCGTTTGAAGGGCTGTTAGCCAATCTGGCTAAAGAA
TACCATTGTAAGGTGTTAGTTAGGGGTTTAAGGGTGGTGAGCGATTTTGAATACGAATTGCAAATGGGCTATGCGAACAA
ATCCTTAAACCACGAATTAGAGACCTTGTATTTCATGCCCACTTTACAAAACGCTTTCATAAGCTCTTCTATCGTGCGAT
CCATTATCGCGCATAAGGGCGATGCGAGCCATTTAGTGCCTAAAGAAATTTATCCTTTGATTTCAAAGGCTTAA

Upstream 100 bases:

>100_bases
AGAGCAAGACTTTAGAAGCGATGCAAGATTTTTTAGTGGGGAAGTGGTTTGACAGCTTAGGGATAGAAAATGACTTATAC
CCACGATGGGGAATGAACTG

Downstream 100 bases:

>100_bases
AATGTATGTGGTGTTAGAAGGCGTTGATGGCGCGGGCAAAAGCACTCAAGTAGAATTATTAAAAGACCGGTTTAAAAACG
CCCTTTTTACCAAAGAGCCA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLDERLKMIQLATKSFKNVECVAFEGLLANLAKE
YHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA

Sequences:

>Translated_157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLDERLKMIQLATKSFKNVECVAFEGLLANLAKE
YHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA
>Mature_157_residues
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLDERLKMIQLATKSFKNVECVAFEGLLANLAKE
YHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=151, Percent_Identity=49.6688741721854, Blast_Score=178, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 17668; Mature: 17668

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLDERLKMIQLATK
CCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCHHHHEEECH
TLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLDERLKMIQLATK
CCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
SFKNVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMP
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCHHHHEEECH
TLQNAFISSSIVRSIIAHKGDASHLVPKEIYPLISKA
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA