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Identifier: 15646004

GI number: 15646004

Start: 1454965

End: 1455819

Strand: Reverse

Name: Not Available

Synonym: HP1394

Alternate gene names: 15646004

Gene position: 1455819-1454965 (Counterclockwise)

Preceding gene: 15646006

Following gene: 15646003

Centisome position: 87.29

GC content: 41.29

Gene sequence:

>855_bases
ATGAAAGATTCACTTCAAACTATCGGCGTGTTTGTGCGGCCCACCCATTATCAAAACCCTCTTTTTGAAAAGCTAGAGCA
GGCTAAAGAATGGGTTTTAAAGCTTTTAGAAGATGAGGGGTTTGAAAGCTTTATGATTGATAGCCTTGATGGGGCAAAAG
ATGCGCGATTGATAGAAAAAGCTGATGCGTTTTTATGTTTAGGGGGCGATGGCACGATTTTAGGGGCTTTAAGAATGACG
CATTCTTACAATAAGCCATGTTTTGGGGTGAGAATTGGGAATTTAGGGTTTTTGAGCGCGGTTGAATTGAATGGTTTGAA
AGATTTCTTACAAGATTTCAAGCAAGATAGGATCAAATTAGAAGAGCATCTGGCTTTAGAGGGCCGTATCGGGAAAACCT
CTTTTTATGCGATCAATGAAATTGTGATCGCCAAAAAAAAAGCTTTAGGGGTTTTAGACATCAAAGCTTATGCAGGCCAT
ACGCCCTTTAACACCTATAAAGGCGATGGGCTTATCATTGCCACGCCCTTAGGCTCGACCGCTTATAATTTGAGTGCTCA
TGGGCCGATTGTGCATGCTTTAAGCCAGAGCTATATTTTAACGCCCTTGTGCGATTTTTCTTTAACGCAACGCCCTTTAG
TGTTAGGAGCGGAATTTTGTTTGAATTTTTGCGCTCATGAAGACGCTCTTGTGGTCATTGATGGGCAAGCCACCTATGAT
TTAAAGGCCAACCAACCCCTATACATTCAAAAAAGCCCCACGACCACCAAGCTCTTACAAAAAAATTCAAGGGATTATTT
TAAAGTGCTTAAAGAAAAGCTCTTATGGGGGGAAAGCCCTAGCAAAAAAAGATAA

Upstream 100 bases:

>100_bases
AAATAAAAACTTTTCATGAATTTTACATAAGATGATAAAAAAGCAATTAAAACCCCCTTTTTTAAAATTTTGTTTCAAGC
TTTAAGCTACAATAGTATGT

Downstream 100 bases:

>100_bases
AAAGGGTAAAAAACATGCGAGATTTCAATAACGCTCAAATCACACGCTTAAAAGTGCGTCAAAACGCTGTTTTTGAAAAA
TTGGATCTGGAGTTTAAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MKDSLQTIGVFVRPTHYQNPLFEKLEQAKEWVLKLLEDEGFESFMIDSLDGAKDARLIEKADAFLCLGGDGTILGALRMT
HSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDFKQDRIKLEEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYAGH
TPFNTYKGDGLIIATPLGSTAYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYD
LKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR

Sequences:

>Translated_284_residues
MKDSLQTIGVFVRPTHYQNPLFEKLEQAKEWVLKLLEDEGFESFMIDSLDGAKDARLIEKADAFLCLGGDGTILGALRMT
HSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDFKQDRIKLEEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYAGH
TPFNTYKGDGLIIATPLGSTAYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYD
LKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR
>Mature_284_residues
MKDSLQTIGVFVRPTHYQNPLFEKLEQAKEWVLKLLEDEGFESFMIDSLDGAKDARLIEKADAFLCLGGDGTILGALRMT
HSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDFKQDRIKLEEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYAGH
TPFNTYKGDGLIIATPLGSTAYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYD
LKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=252, Percent_Identity=25.3968253968254, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1788968, Length=291, Percent_Identity=26.8041237113402, Blast_Score=107, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6320794, Length=255, Percent_Identity=25.0980392156863, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325068, Length=166, Percent_Identity=32.5301204819277, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322509, Length=240, Percent_Identity=25.8333333333333, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573828, Length=276, Percent_Identity=27.536231884058, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573830, Length=282, Percent_Identity=27.3049645390071, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573832, Length=276, Percent_Identity=27.536231884058, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI161077047, Length=276, Percent_Identity=27.536231884058, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28573826, Length=282, Percent_Identity=27.3049645390071, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI20129957, Length=281, Percent_Identity=24.9110320284698, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281363321, Length=281, Percent_Identity=24.9110320284698, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281363323, Length=281, Percent_Identity=24.9110320284698, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24653424, Length=287, Percent_Identity=24.7386759581882, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24653422, Length=287, Percent_Identity=24.7386759581882, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 31632; Mature: 31632

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDSLQTIGVFVRPTHYQNPLFEKLEQAKEWVLKLLEDEGFESFMIDSLDGAKDARLIEK
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
ADAFLCLGGDGTILGALRMTHSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDFKQDRIKL
CCEEEEECCCCEEEEEEEHHCCCCCCEEEEEECCCCEEEHEEHHHHHHHHHHHHHHHHHH
EEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYAGHTPFNTYKGDGLIIATPLGST
HHHEEECCCCCCCHHHHHHHHEEEHHHHCCEEEEHHHCCCCCCCCCCCCCEEEEECCCCC
AYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYD
EEECCCCCHHHHHHCCCEEECCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEECCCEEEE
LKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR
ECCCCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKDSLQTIGVFVRPTHYQNPLFEKLEQAKEWVLKLLEDEGFESFMIDSLDGAKDARLIEK
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
ADAFLCLGGDGTILGALRMTHSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDFKQDRIKL
CCEEEEECCCCEEEEEEEHHCCCCCCEEEEEECCCCEEEHEEHHHHHHHHHHHHHHHHHH
EEHLALEGRIGKTSFYAINEIVIAKKKALGVLDIKAYAGHTPFNTYKGDGLIIATPLGST
HHHEEECCCCCCCHHHHHHHHEEEHHHHCCEEEEHHHCCCCCCCCCCCCCEEEEECCCCC
AYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYD
EEECCCCCHHHHHHCCCEEECCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEECCCEEEE
LKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR
ECCCCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA