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Identifier: 15645995

GI number: 15645995

Start: 1447156

End: 1448028

Strand: Reverse

Name: Not Available

Synonym: HP1385

Alternate gene names: 15645995

Gene position: 1448028-1447156 (Counterclockwise)

Preceding gene: 15646000

Following gene: 15645994

Centisome position: 86.82

GC content: 37.0

Gene sequence:

>873_bases
ATGGATTACAAATGTTTTAAAGGCAAGCATGCGAACATCGTTATAGAAATCATCAGTCTTTTAGAAAAAGGGGTTAAAAA
AGCCCAAGAAATTTTAGAAAAACCAGACGCTGGGAGTTACACGAAGTTAGAAAACAGCAGCGGGGATACGCCTATTAAAG
CGGATTTAGCCCTAGATAAGTTTTTAGAAGAAAATTTTTTGAGTTTAGAAAACATCAAAAGCGTTTTTAGCGAAGAAAAA
GAAACGCCTGTTACTAAAGAAAACGGCTCTTATTTGATCGCTTATGACCCCTTAGATGGGAGTTCAGTGATGGAGGCGAA
TTTCTTAGTAGGCACGATTATAGGGATTTATGAAAAGGATTATAAGGCGCAAAATCTAGCCGCAAGCCTTTATGTGGTTT
TTGGGCATAAAATTGAATTAGTGGTGGCTTTAGAAGAAGTTTATCGTTACTCGTTTTACCAAAACAAGTTCCATTTTATA
GAAACCATCGTTTTAGAAAATAAGGGTAAAATCGTCGCTAGCGGAGGCAATCAAAAGGATTTTTCTTTGGGCTTAAAAAA
GGCTTTAGAAGGGTTTTTTGCAGAAAATTACCGCTTACGATACTCAGGATCTATGGTGGCTGATGTCCATCATGTGTTGG
TTAAAAAAGGCGGAATGTTTTCCTACCCGCAAAAGAAATTGCGAAAGCTTTTTGAAGTCTTCCCTTTAGCCTTGATGGTT
GAAAAAGCTAAAGGGGAAGCGTTTTATTTTGATAAGGGGGTTAAAAAGCGTTTGCTAGAACAAAGCGTAGAAAACTATCA
TGAAAAAAGCGAATGCTATTTAGCCAGCCAGCATGAAGCTCACATTTTAGAAAAATATTTAAAGGGAGAATGA

Upstream 100 bases:

>100_bases
AGCGCTCAAAAGGCTCGGAGCTACTTTCAAAATACTTCCCTATTTTCAATGTTTTCAAGTAAAATATTAGCATCTTTAAT
CAAATCATAAAAGGGTTTTT

Downstream 100 bases:

>100_bases
TGCAAAATAGCGTTAAAAAATTAGAATATGAAGAGCGTTTCAATGACGCTCTTTTGAAATTACAAGCATGCCAAGAAGAA
AAGCAGGTAACGAGTTGTTT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MDYKCFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDKFLEENFLSLENIKSVFSEEK
ETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGIYEKDYKAQNLAASLYVVFGHKIELVVALEEVYRYSFYQNKFHFI
ETIVLENKGKIVASGGNQKDFSLGLKKALEGFFAENYRLRYSGSMVADVHHVLVKKGGMFSYPQKKLRKLFEVFPLALMV
EKAKGEAFYFDKGVKKRLLEQSVENYHEKSECYLASQHEAHILEKYLKGE

Sequences:

>Translated_290_residues
MDYKCFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDKFLEENFLSLENIKSVFSEEK
ETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGIYEKDYKAQNLAASLYVVFGHKIELVVALEEVYRYSFYQNKFHFI
ETIVLENKGKIVASGGNQKDFSLGLKKALEGFFAENYRLRYSGSMVADVHHVLVKKGGMFSYPQKKLRKLFEVFPLALMV
EKAKGEAFYFDKGVKKRLLEQSVENYHEKSECYLASQHEAHILEKYLKGE
>Mature_290_residues
MDYKCFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDKFLEENFLSLENIKSVFSEEK
ETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGIYEKDYKAQNLAASLYVVFGHKIELVVALEEVYRYSFYQNKFHFI
ETIVLENKGKIVASGGNQKDFSLGLKKALEGFFAENYRLRYSGSMVADVHHVLVKKGGMFSYPQKKLRKLFEVFPLALMV
EKAKGEAFYFDKGVKKRLLEQSVENYHEKSECYLASQHEAHILEKYLKGE

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=309, Percent_Identity=29.126213592233, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI16579888, Length=309, Percent_Identity=29.126213592233, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI22907028, Length=313, Percent_Identity=26.8370607028754, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1790679, Length=278, Percent_Identity=29.4964028776978, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508131, Length=322, Percent_Identity=27.0186335403727, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323409, Length=275, Percent_Identity=30.1818181818182, Blast_Score=96, Evalue=7e-21,
Organism=Drosophila melanogaster, GI45550998, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19921562, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR023079 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 32949; Mature: 32949

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYKCFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEHHHHHHH
FLEENFLSLENIKSVFSEEKETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGIYEKD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
YKAQNLAASLYVVFGHKIELVVALEEVYRYSFYQNKFHFIETIVLENKGKIVASGGNQKD
CHHHHHHHEEEEEECCEEEEEHHHHHHHHHHHHCCHHHHHHEEEEECCCEEEECCCCCCH
FSLGLKKALEGFFAENYRLRYSGSMVADVHHVLVKKGGMFSYPQKKLRKLFEVFPLALMV
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EKAKGEAFYFDKGVKKRLLEQSVENYHEKSECYLASQHEAHILEKYLKGE
HHCCCCEEEECHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MDYKCFKGKHANIVIEIISLLEKGVKKAQEILEKPDAGSYTKLENSSGDTPIKADLALDK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEHHHHHHH
FLEENFLSLENIKSVFSEEKETPVTKENGSYLIAYDPLDGSSVMEANFLVGTIIGIYEKD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
YKAQNLAASLYVVFGHKIELVVALEEVYRYSFYQNKFHFIETIVLENKGKIVASGGNQKD
CHHHHHHHEEEEEECCEEEEEHHHHHHHHHHHHCCHHHHHHEEEEECCCEEEECCCCCCH
FSLGLKKALEGFFAENYRLRYSGSMVADVHHVLVKKGGMFSYPQKKLRKLFEVFPLALMV
HHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EKAKGEAFYFDKGVKKRLLEQSVENYHEKSECYLASQHEAHILEKYLKGE
HHCCCCEEEECHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA