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Identifier: 15645969

GI number: 15645969

Start: 1418889

End: 1419692

Strand: Reverse

Name: Not Available

Synonym: HP1357

Alternate gene names: 15645969

Gene position: 1419692-1418889 (Counterclockwise)

Preceding gene: 15645970

Following gene: 15645968

Centisome position: 85.12

GC content: 39.3

Gene sequence:

>804_bases
ATGGTAGCTTTAAGCAACGCTCTTTCAAGGGTTTTTGGCTCTCTCGCTGGTTATAAATTCCCTTCTTTTATCCAAAAAGG
CATCAACGCCCTTTATGTTAAGATCTTTAAAATTGATTTGAGTGAGTTTGAGCCTTTAGAAAATTATAGGAGTTTGAACG
CTCTTTTCACGCGCTCTTTAAAAAAAGAACGCCCCTTTGACAAATCCCCTAATATTTGCATCGCGCCTTGCGACGCTTTG
ATCACTGAATGCGCTTTTTTAGACAACGATAGCGCTTTACAGATTAAAGGCATGCCTTATAAAGCGCATGAATTAGTGGG
CGAAATCAACCCCTTAAGCCCTTCTTTTTTCTATGCGAATTTTTACCTTTCGCCCAAAGATTACCACCACTACCACGCCC
CTTGCGATTTAGAAATTTTAGAGGCTCGTTATTTTGCGGGGAAATTACTACCGGTCAATAAGCCCTCATTACACAAAAAC
AACAATCTGTTTGTGGGCAATGAAAGGGTCACACTTGTTGCAAAAGACATTCAAGGCAATAGGTTGTATTTTGTAGCGGT
GGGAGCGTTAAATGTGGGTAAAATGCGTTTTAATTTTGATAAGAATATCCAAACTAACGCTAAAGCCCGTTTCACGCAAA
CCTACTCTTACAACCCGCCGATCAAGGTTAAAAAAGGGGATAATTTAGGGAATTTTGAAATGGGCTCTACTATCGTTTTA
TTCATTCAAAACACCGCTTTTAAAGATTTGAAAGAAAAAAACGTGAAGTTTGGGGAAAGTATAGGGGAATTTCATGCCAA
CTGA

Upstream 100 bases:

>100_bases
TGAAAATGTATCAAGAGGGTTATAGCGTGGATTCTATTTCTAAAGAATTTAAAGTGAGTAAGGGCGAGGTGGAGTTTATA
CTGAATATGGCAGGGTTAAA

Downstream 100 bases:

>100_bases
TAACGATTTAAAAGCTGCTATTTTGGAATTATTGCGCGATTTGGACGTGCTTTTAGTGGCTCATTTTTACCAAAAAGATG
AGATTGTAGAGTTAGCCCAT

Product: phosphatidylserine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MVALSNALSRVFGSLAGYKFPSFIQKGINALYVKIFKIDLSEFEPLENYRSLNALFTRSLKKERPFDKSPNICIAPCDAL
ITECAFLDNDSALQIKGMPYKAHELVGEINPLSPSFFYANFYLSPKDYHHYHAPCDLEILEARYFAGKLLPVNKPSLHKN
NNLFVGNERVTLVAKDIQGNRLYFVAVGALNVGKMRFNFDKNIQTNAKARFTQTYSYNPPIKVKKGDNLGNFEMGSTIVL
FIQNTAFKDLKEKNVKFGESIGEFHAN

Sequences:

>Translated_267_residues
MVALSNALSRVFGSLAGYKFPSFIQKGINALYVKIFKIDLSEFEPLENYRSLNALFTRSLKKERPFDKSPNICIAPCDAL
ITECAFLDNDSALQIKGMPYKAHELVGEINPLSPSFFYANFYLSPKDYHHYHAPCDLEILEARYFAGKLLPVNKPSLHKN
NNLFVGNERVTLVAKDIQGNRLYFVAVGALNVGKMRFNFDKNIQTNAKARFTQTYSYNPPIKVKKGDNLGNFEMGSTIVL
FIQNTAFKDLKEKNVKFGESIGEFHAN
>Mature_267_residues
MVALSNALSRVFGSLAGYKFPSFIQKGINALYVKIFKIDLSEFEPLENYRSLNALFTRSLKKERPFDKSPNICIAPCDAL
ITECAFLDNDSALQIKGMPYKAHELVGEINPLSPSFFYANFYLSPKDYHHYHAPCDLEILEARYFAGKLLPVNKPSLHKN
NNLFVGNERVTLVAKDIQGNRLYFVAVGALNVGKMRFNFDKNIQTNAKARFTQTYSYNPPIKVKKGDNLGNFEMGSTIVL
FIQNTAFKDLKEKNVKFGESIGEFHAN

Specific function: Unknown

COG id: COG0688

COG function: function code I; Phosphatidylserine decarboxylase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI13489112, Length=296, Percent_Identity=29.3918918918919, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI1790604, Length=240, Percent_Identity=30.8333333333333, Blast_Score=111, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71980843, Length=250, Percent_Identity=29.2, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71980840, Length=250, Percent_Identity=29.2, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324160, Length=168, Percent_Identity=37.5, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321609, Length=275, Percent_Identity=26.1818181818182, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24649526, Length=296, Percent_Identity=28.3783783783784, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24649528, Length=296, Percent_Identity=28.3783783783784, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24649524, Length=296, Percent_Identity=28.3783783783784, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003817
- InterPro:   IPR005221 [H]

Pfam domain/function: PF02666 PS_Dcarbxylase [H]

EC number: =4.1.1.65 [H]

Molecular weight: Translated: 30201; Mature: 30201

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVALSNALSRVFGSLAGYKFPSFIQKGINALYVKIFKIDLSEFEPLENYRSLNALFTRSL
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEEEEEHHHCCCHHHHHHHHHHHHHHH
KKERPFDKSPNICIAPCDALITECAFLDNDSALQIKGMPYKAHELVGEINPLSPSFFYAN
HHCCCCCCCCCEEEECHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCCCCEEEEE
FYLSPKDYHHYHAPCDLEILEARYFAGKLLPVNKPSLHKNNNLFVGNERVTLVAKDIQGN
EEECCCCCCCCCCCCCCEEEEEHHHCCEEEECCCCCCCCCCCEEECCCEEEEEEEECCCC
RLYFVAVGALNVGKMRFNFDKNIQTNAKARFTQTYSYNPPIKVKKGDNLGNFEMGSTIVL
EEEEEEEECEEECEEEEECCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCEECCCEEEE
FIQNTAFKDLKEKNVKFGESIGEFHAN
EEECCHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MVALSNALSRVFGSLAGYKFPSFIQKGINALYVKIFKIDLSEFEPLENYRSLNALFTRSL
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEEEEEEHHHCCCHHHHHHHHHHHHHHH
KKERPFDKSPNICIAPCDALITECAFLDNDSALQIKGMPYKAHELVGEINPLSPSFFYAN
HHCCCCCCCCCEEEECHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCCCCEEEEE
FYLSPKDYHHYHAPCDLEILEARYFAGKLLPVNKPSLHKNNNLFVGNERVTLVAKDIQGN
EEECCCCCCCCCCCCCCEEEEEHHHCCEEEECCCCCCCCCCCEEECCCEEEEEEEECCCC
RLYFVAVGALNVGKMRFNFDKNIQTNAKARFTQTYSYNPPIKVKKGDNLGNFEMGSTIVL
EEEEEEEECEEECEEEEECCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCEECCCEEEE
FIQNTAFKDLKEKNVKFGESIGEFHAN
EEECCHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA