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Identifier: 15645651

GI number: 15645651

Start: 1097475

End: 1098548

Strand: Reverse

Name: Not Available

Synonym: HP1037

Alternate gene names: 15645651

Gene position: 1098548-1097475 (Counterclockwise)

Preceding gene: 15645652

Following gene: 15645650

Centisome position: 65.87

GC content: 41.43

Gene sequence:

>1074_bases
ATGAAAGGATTAGAAAGAGAATCGCATTTCACGCTCAATGAGAATGCGATGTTTTTTGAGTGTGCTTATAGTTGCGATAA
CGCTTTGTTTTTGCAATTAGACGATCGCTCGTTTTTTATCACTGATTCTCGCTACACTCAAGAAGCTAAAGAAAGCGTTC
AGCCTAAAAATGGCGTTTTAGCGGAAGTGGTAGAATCTAGCGATTTAGTGCAAAGCGCGATTGATTTGATTGTTAAAAGT
TCGGTTAAAAAACTCTTTTTTGACCCCAATCAAGTGAATTTACAAACCTACAAGCGTTTAAATTCAGCGCTTGGGGATAA
GGTTGCTTTAGAGGGCGTGCCTAGTTACCACCGCCAAAAACGCATCATTAAAAACGAGCATGAAATCCAACTTCTCAAAA
AATCTCAAGCGCTGAATGTTGAAGCTTTTGAAAATTTTGCCGAGTATGTGAAAAAGATTTTTGATGAAAAAGAGTCGTTG
AGCGAGCGGTATTTGCAGCATAAGGTTAAGGACTTTTTGACTAGAGAGGGGGTTTATGATCTGAGCTTTGAGCCTATTTT
AGCCTTGAATGCGAACGCGAGCAAGCCCCATGCTTTGCCTAGTGCGAAGGATTTTTTAAAAGCGGAGCACAGCATTCTTT
TGGATATGGGGATCAAATACGAACGCTATTGCTCTGATAGGACTCGCACGGCTTTTTTTGACCCTAAAGATTTTGTCTTT
AAAAGAGAGCAGAGTTTCAAGGATAAAGAGCGTCAAAAGATTTATGACATTGTGAAAGAAGCGCAAGAAAAGGCTATTTC
AGGCATTAGAGCGGGCATGACCGGTAAAGAAGCGGACAGCTTGGCTAGGGGAGTGATTAGCGATTATGGTTATGGGCAAT
ATTTCACTCACAGCACCGGGCATGGCATTGGCTTAGACATCCATGAGCTTCCCTATATTTCATCGCGCAGTGAAACCATT
TTAGAAGAGGGCATGGTGTTTTCTGTAGAGCCTGGGATTTATATCCCTGGGTTTTTTGGGGTGCGCATTGAAGATTTAGT
GGTGATCAAAAATTCTAGGTCTGAGCTTTTGTGA

Upstream 100 bases:

>100_bases
GCGATGGTCAATATTTTAGCCGAAATGAAAGCGTTCCAAGAAGCCCAAAAAAACAACCCTAATAACCCCATTAACAATCA
AAAATAAAAGGGGGCTACCC

Downstream 100 bases:

>100_bases
TGCGAGAGATCCTTACTAGCCGCTTTTTCCCTAGCCTTTTTAAAAAAAGGCTTGATTTTTCTAACAGGGTGGTTTTAGGG
TTGGGATCTAATCTTAAAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKGLERESHFTLNENAMFFECAYSCDNALFLQLDDRSFFITDSRYTQEAKESVQPKNGVLAEVVESSDLVQSAIDLIVKS
SVKKLFFDPNQVNLQTYKRLNSALGDKVALEGVPSYHRQKRIIKNEHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESL
SERYLQHKVKDFLTREGVYDLSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
KREQSFKDKERQKIYDIVKEAQEKAISGIRAGMTGKEADSLARGVISDYGYGQYFTHSTGHGIGLDIHELPYISSRSETI
LEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRSELL

Sequences:

>Translated_357_residues
MKGLERESHFTLNENAMFFECAYSCDNALFLQLDDRSFFITDSRYTQEAKESVQPKNGVLAEVVESSDLVQSAIDLIVKS
SVKKLFFDPNQVNLQTYKRLNSALGDKVALEGVPSYHRQKRIIKNEHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESL
SERYLQHKVKDFLTREGVYDLSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
KREQSFKDKERQKIYDIVKEAQEKAISGIRAGMTGKEADSLARGVISDYGYGQYFTHSTGHGIGLDIHELPYISSRSETI
LEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRSELL
>Mature_357_residues
MKGLERESHFTLNENAMFFECAYSCDNALFLQLDDRSFFITDSRYTQEAKESVQPKNGVLAEVVESSDLVQSAIDLIVKS
SVKKLFFDPNQVNLQTYKRLNSALGDKVALEGVPSYHRQKRIIKNEHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESL
SERYLQHKVKDFLTREGVYDLSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
KREQSFKDKERQKIYDIVKEAQEKAISGIRAGMTGKEADSLARGVISDYGYGQYFTHSTGHGIGLDIHELPYISSRSETI
LEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRSELL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI264681563, Length=257, Percent_Identity=27.2373540856031, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI11559925, Length=278, Percent_Identity=26.6187050359712, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI93141226, Length=250, Percent_Identity=28, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788728, Length=324, Percent_Identity=32.4074074074074, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1789275, Length=310, Percent_Identity=25.4838709677419, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17509539, Length=361, Percent_Identity=25.7617728531856, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320922, Length=252, Percent_Identity=24.2063492063492, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321118, Length=252, Percent_Identity=23.015873015873, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40797; Mature: 40797

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLERESHFTLNENAMFFECAYSCDNALFLQLDDRSFFITDSRYTQEAKESVQPKNGVL
CCCCCCCCCEEECCCCEEEEEEECCCCEEEEEECCCEEEEECCHHHHHHHHHCCCCCCHH
AEVVESSDLVQSAIDLIVKSSVKKLFFDPNQVNLQTYKRLNSALGDKVALEGVPSYHRQK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHH
RIIKNEHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESLSERYLQHKVKDFLTREGVYD
HHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
LSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
CCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEECCCCHHHHH
KREQSFKDKERQKIYDIVKEAQEKAISGIRAGMTGKEADSLARGVISDYGYGQYFTHSTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEECCCC
HGIGLDIHELPYISSRSETILEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRSELL
CCCCCCHHHCCCCCCCHHHHHHCCCEEEECCCEEECCCCCCEEEEEEEEECCHHCCC
>Mature Secondary Structure
MKGLERESHFTLNENAMFFECAYSCDNALFLQLDDRSFFITDSRYTQEAKESVQPKNGVL
CCCCCCCCCEEECCCCEEEEEEECCCCEEEEEECCCEEEEECCHHHHHHHHHCCCCCCHH
AEVVESSDLVQSAIDLIVKSSVKKLFFDPNQVNLQTYKRLNSALGDKVALEGVPSYHRQK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCCCHHHHH
RIIKNEHEIQLLKKSQALNVEAFENFAEYVKKIFDEKESLSERYLQHKVKDFLTREGVYD
HHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
LSFEPILALNANASKPHALPSAKDFLKAEHSILLDMGIKYERYCSDRTRTAFFDPKDFVF
CCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEECCCCHHHHH
KREQSFKDKERQKIYDIVKEAQEKAISGIRAGMTGKEADSLARGVISDYGYGQYFTHSTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEECCCC
HGIGLDIHELPYISSRSETILEEGMVFSVEPGIYIPGFFGVRIEDLVVIKNSRSELL
CCCCCCHHHCCCCCCCHHHHHHCCCEEEECCCEEECCCCCCEEEEEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]