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Identifier: 15645610

GI number: 15645610

Start: 1056158

End: 1057225

Strand: Reverse

Name: Not Available

Synonym: HP0995

Alternate gene names: 15645610

Gene position: 1057225-1056158 (Counterclockwise)

Preceding gene: 15645611

Following gene: 15645607

Centisome position: 63.39

GC content: 31.55

Gene sequence:

>1068_bases
ATGCCACATAACAAACTCACTAAATCTCAGAGAGAACTCTTTTGTAATCTCAAAGCCTTTTTATACACTAAGGCTAAAAA
CTTCACGCCCATTCAAGATGTGAAGGATATGGCTTTAATCCTAGACACACAAGATAAAATCTTAAAATGTCATAATATAG
AGCAATTAAAACAACTCTGTCATATTCTTTATAATCAAGGCATTAAACACACTATAATGATGCAAGGCTTGTTTTTATTC
TTTAACTATTTTAAAGATAATCTCAAATTAAGAAGTTTTAGAATGCTTAGCGAAGAGCAAGTGATTAACTTTCTCTTTGA
ACTCGCTCAAAATAGAAAACCCAGCTCTATGGCTAAGTATGTGATGTATTTAAGACAATTCTTTGATTATTTGGATAGAA
AAAGGCGTTATAGCTTTGATTTTACGCTTAAAAACCTAGCCTTTGCTAAGACCAAAGAAAGCTTACCCAGACATTTAAAC
GATAAAGACTTAAAGAGTTTTTTAAAAACACTCTTAGACTATAAGCCAGCTACAAGCTTTGAAAAACGCAATAAGTGTAT
TCTACTTATTGTAATACTTGGTGGACTTAGAAAATGCGAAGTGTTAAACATAGAATTAAAACACATTCAAGTAGAAGAGC
AAAACTACTCTATTTTAATTCAAGGTAAAGGTAGAAAAGAGAGAAAAGCTTATATTAAAAAGAGTTTGTTAGAACCAAGC
TTGAATGCTTGGCTTAGTGATGAATATAGACTAAAATATTTTAATGGGGCATATCTTTTTAAAAAAGACAAACAAAAAGC
ACAAAATTCTTTAACGCTTTATAGCTTTATCCCCTTAATCTTTAAACTAGCTCAAATCAAACACTATAAGCAATATGGCA
CAGGCTTACATCTATTTAGGCATAGTTTTGCAACACTCATTTATCAAGAAACCCAAGACTTAGTTTTAACTTCAAGGGCG
TTAGGGCATAGCTCCTTACTCTCTACTAAGATTTATATTCATACTACACAAGAGCATAACAAGAAAGTGGCTCTTGTGTT
TGATAGTTTGATAGAGGACAAGAAGTAA

Upstream 100 bases:

>100_bases
GCAAAATTTTTAAAAATACCGCTTTTAGAACCTAACAAACTAAAAAACATAAAACTCTCATTCTTTAAGATTTCTTTTTA
TATTTTAATAAGGGAGCAAT

Downstream 100 bases:

>100_bases
GGTGGTTAAAATTGATTAGGTAGTTTAGTGTAATTAGTTTAAATAATCTTATTAAGATAAATAATCTAGCATTAGATAGT
TTTAATTAACTATTTAATGT

Product: integrase/recombinase (xerD)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MPHNKLTKSQRELFCNLKAFLYTKAKNFTPIQDVKDMALILDTQDKILKCHNIEQLKQLCHILYNQGIKHTIMMQGLFLF
FNYFKDNLKLRSFRMLSEEQVINFLFELAQNRKPSSMAKYVMYLRQFFDYLDRKRRYSFDFTLKNLAFAKTKESLPRHLN
DKDLKSFLKTLLDYKPATSFEKRNKCILLIVILGGLRKCEVLNIELKHIQVEEQNYSILIQGKGRKERKAYIKKSLLEPS
LNAWLSDEYRLKYFNGAYLFKKDKQKAQNSLTLYSFIPLIFKLAQIKHYKQYGTGLHLFRHSFATLIYQETQDLVLTSRA
LGHSSLLSTKIYIHTTQEHNKKVALVFDSLIEDKK

Sequences:

>Translated_355_residues
MPHNKLTKSQRELFCNLKAFLYTKAKNFTPIQDVKDMALILDTQDKILKCHNIEQLKQLCHILYNQGIKHTIMMQGLFLF
FNYFKDNLKLRSFRMLSEEQVINFLFELAQNRKPSSMAKYVMYLRQFFDYLDRKRRYSFDFTLKNLAFAKTKESLPRHLN
DKDLKSFLKTLLDYKPATSFEKRNKCILLIVILGGLRKCEVLNIELKHIQVEEQNYSILIQGKGRKERKAYIKKSLLEPS
LNAWLSDEYRLKYFNGAYLFKKDKQKAQNSLTLYSFIPLIFKLAQIKHYKQYGTGLHLFRHSFATLIYQETQDLVLTSRA
LGHSSLLSTKIYIHTTQEHNKKVALVFDSLIEDKK
>Mature_354_residues
PHNKLTKSQRELFCNLKAFLYTKAKNFTPIQDVKDMALILDTQDKILKCHNIEQLKQLCHILYNQGIKHTIMMQGLFLFF
NYFKDNLKLRSFRMLSEEQVINFLFELAQNRKPSSMAKYVMYLRQFFDYLDRKRRYSFDFTLKNLAFAKTKESLPRHLND
KDLKSFLKTLLDYKPATSFEKRNKCILLIVILGGLRKCEVLNIELKHIQVEEQNYSILIQGKGRKERKAYIKKSLLEPSL
NAWLSDEYRLKYFNGAYLFKKDKQKAQNSLTLYSFIPLIFKLAQIKHYKQYGTGLHLFRHSFATLIYQETQDLVLTSRAL
GHSSLLSTKIYIHTTQEHNKKVALVFDSLIEDKK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=281, Percent_Identity=25.9786476868327, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789261, Length=232, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 42086; Mature: 41955

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHNKLTKSQRELFCNLKAFLYTKAKNFTPIQDVKDMALILDTQDKILKCHNIEQLKQLC
CCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHEEECCHHHHHHHCCHHHHHHHH
HILYNQGIKHTIMMQGLFLFFNYFKDNLKLRSFRMLSEEQVINFLFELAQNRKPSSMAKY
HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VMYLRQFFDYLDRKRRYSFDFTLKNLAFAKTKESLPRHLNDKDLKSFLKTLLDYKPATSF
HHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCH
EKRNKCILLIVILGGLRKCEVLNIELKHIQVEEQNYSILIQGKGRKERKAYIKKSLLEPS
HHCCCEEEEEEECCCCCEEEEEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCC
LNAWLSDEYRLKYFNGAYLFKKDKQKAQNSLTLYSFIPLIFKLAQIKHYKQYGTGLHLFR
HHHHCCCCEEEEEECCEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
HSFATLIYQETQDLVLTSRALGHSSLLSTKIYIHTTQEHNKKVALVFDSLIEDKK
HHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEEEECCCCCCEEEEEEHHHHCCCC
>Mature Secondary Structure 
PHNKLTKSQRELFCNLKAFLYTKAKNFTPIQDVKDMALILDTQDKILKCHNIEQLKQLC
CCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHEEECCHHHHHHHCCHHHHHHHH
HILYNQGIKHTIMMQGLFLFFNYFKDNLKLRSFRMLSEEQVINFLFELAQNRKPSSMAKY
HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VMYLRQFFDYLDRKRRYSFDFTLKNLAFAKTKESLPRHLNDKDLKSFLKTLLDYKPATSF
HHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCH
EKRNKCILLIVILGGLRKCEVLNIELKHIQVEEQNYSILIQGKGRKERKAYIKKSLLEPS
HHCCCEEEEEEECCCCCEEEEEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHCCCC
LNAWLSDEYRLKYFNGAYLFKKDKQKAQNSLTLYSFIPLIFKLAQIKHYKQYGTGLHLFR
HHHHCCCCEEEEEECCEEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
HSFATLIYQETQDLVLTSRALGHSSLLSTKIYIHTTQEHNKKVALVFDSLIEDKK
HHHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEEEECCCCCCEEEEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]