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Identifier: 15645565

GI number: 15645565

Start: 1010222

End: 1010674

Strand: Reverse

Name: Not Available

Synonym: HP0949

Alternate gene names: 15645565

Gene position: 1010674-1010222 (Counterclockwise)

Preceding gene: 15645566

Following gene: 15645564

Centisome position: 60.6

GC content: 36.42

Gene sequence:

>453_bases
ATGCGTTGCGTGGTGTATTCTATCGCTAAAAGTTCGCCTTTAGAGTTAGTGAAAATCTATCAAAAGCAATGCAGGCAATT
TGATTGCGAGCTGGAATTGGTGGATTTATTCCCTAAAAATACCGCCAACGCTCAAAAAGTTTCTAAAAAACTGGCTCAAA
AAAGCTACTCTCTAGCTTTTGAGCCGTATTTAAACCCTAAGGCAAAAAATATCGCCTTACACCCTAAAGCTCAAAGGGGC
GATAGCTTTGCGTTTAGTAAAATGTTAGAAAATCATCTTAATATTAATTTTTTTATCGCTGGAGCGTATGGGTTTGAAGA
AAATTTTTTAAAGGATTGTCAAGCTTGGAGTTTGAGCGAGATGACTTTTAGCCATGAAGTGGCTAAAATTGTCTTATGCG
AGCAAATCTATAGGGCTTTAAGCATTATTTTTAAGCATCCATACCATAAATAG

Upstream 100 bases:

>100_bases
GATATGATTGTGCACAGGAAGGATTTGAAGAAGACTTTGAGCGATCTCATCGCTATGATGACGCATAAGACTTCAAAGAT
TTTTTAAAGTTTTAACATTG

Downstream 100 bases:

>100_bases
GAGGTGCGCATGCGTTTTTACATTATCTTTACATTTTTGTTTATTGTGGGTTTTGGTGTGTTTGTTTATAGTATTGATCC
GCAAGCTTACGCCTTTAATT

Product: rRNA large subunit methyltransferase

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MRCVVYSIAKSSPLELVKIYQKQCRQFDCELELVDLFPKNTANAQKVSKKLAQKSYSLAFEPYLNPKAKNIALHPKAQRG
DSFAFSKMLENHLNINFFIAGAYGFEENFLKDCQAWSLSEMTFSHEVAKIVLCEQIYRALSIIFKHPYHK

Sequences:

>Translated_150_residues
MRCVVYSIAKSSPLELVKIYQKQCRQFDCELELVDLFPKNTANAQKVSKKLAQKSYSLAFEPYLNPKAKNIALHPKAQRG
DSFAFSKMLENHLNINFFIAGAYGFEENFLKDCQAWSLSEMTFSHEVAKIVLCEQIYRALSIIFKHPYHK
>Mature_150_residues
MRCVVYSIAKSSPLELVKIYQKQCRQFDCELELVDLFPKNTANAQKVSKKLAQKSYSLAFEPYLNPKAKNIALHPKAQRG
DSFAFSKMLENHLNINFFIAGAYGFEENFLKDCQAWSLSEMTFSHEVAKIVLCEQIYRALSIIFKHPYHK

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA [H]

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003742 [H]

Pfam domain/function: PF02590 SPOUT_MTase [H]

EC number: NA

Molecular weight: Translated: 17331; Mature: 17331

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCVVYSIAKSSPLELVKIYQKQCRQFDCELELVDLFPKNTANAQKVSKKLAQKSYSLAF
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCEEE
EPYLNPKAKNIALHPKAQRGDSFAFSKMLENHLNINFFIAGAYGFEENFLKDCQAWSLSE
CCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHCCCCHHH
MTFSHEVAKIVLCEQIYRALSIIFKHPYHK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRCVVYSIAKSSPLELVKIYQKQCRQFDCELELVDLFPKNTANAQKVSKKLAQKSYSLAF
CCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCEEE
EPYLNPKAKNIALHPKAQRGDSFAFSKMLENHLNINFFIAGAYGFEENFLKDCQAWSLSE
CCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHCCCCHHH
MTFSHEVAKIVLCEQIYRALSIIFKHPYHK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA