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Identifier: 15645566

GI number: 15645566

Start: 1010688

End: 1011557

Strand: Reverse

Name: Not Available

Synonym: HP0950

Alternate gene names: 15645566

Gene position: 1011557-1010688 (Counterclockwise)

Preceding gene: 15645569

Following gene: 15645565

Centisome position: 60.65

GC content: 43.22

Gene sequence:

>870_bases
ATGGGATTTGCAGATTTCTTTAAAAATTTTAAGATCAATAAATTGCGGACAGCGCCAAGTAAGGAAGAACAGCCAAGCCA
TTGGGTGAAATGCCCTAAATGTTATGCGTTAATGTATCATAAAGAAGTGTTTAGTAAATACAGCGTGTGTTTGAAATGCC
ATTACCATTTCCGCATGAAAGCGGCTGAAAGGATTGAATTTTTATGCGATGTGGGGAGTTTTGAAGAGTTTGACAAGCAT
TTACGGCCTAATGATCCTTTAAATTTCGTGGATAAAGAGAGCTATAAACAACGCATTAAAAAATACGAAAAAAGGACTAA
CCGCCCAAGCTCAGTGATCAGCGGTGAGGCTAAAATCAACCGCATGCCTTTGCAGATCGTGGTGTTTGATTTTAGCTTTA
TGGGGGGGAGTTTAGGCTCTGTGGAGGGCGAAAAGATCGTAAGAGCAATCAATCGCGCGGTCGCTAAAAGAGAAGCGTTA
TTGATTGTTTCAGCGAGTGGGGGGGCTAGGATGCAAGAATCCACTTATTCGCTCATGCAAATGGCTAAAACGAGCGCGGC
TTTGAACCGATTGAGTGAGGCCAAACTCCCTTTCATTTCGCTCTTAAGCGATCCCACTTATGGGGGCGTTAGCGCATCTT
TTGCTTTTTTAGGGGATCTCATTATCGCAGAGCCAGGGGCGATGATAGGCTTTGCGGGGCCTAGGGTGATTAAGCAAACT
ATAGGGGCGGATTTGCCTGAGGGCTTTCAAACAGCGGAATTTTTATTAGAGCATGGCTTGATTGATATGATTGTGCACAG
GAAGGATTTGAAGAAGACTTTGAGCGATCTCATCGCTATGATGACGCATAAGACTTCAAAGATTTTTTAA

Upstream 100 bases:

>100_bases
TGTAAAAGAAACCCTTGCATCACTACTCTTAAGCTAATTTTGTTTATTATAAGCAAAACTTGGATACAATCCTAACAAAA
CTGCAAAATTAAGGAAAAAC

Downstream 100 bases:

>100_bases
AGTTTTAACATTGATGCGTTGCGTGGTGTATTCTATCGCTAAAAGTTCGCCTTTAGAGTTAGTGAAAATCTATCAAAAGC
AATGCAGGCAATTTGATTGC

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MGFADFFKNFKINKLRTAPSKEEQPSHWVKCPKCYALMYHKEVFSKYSVCLKCHYHFRMKAAERIEFLCDVGSFEEFDKH
LRPNDPLNFVDKESYKQRIKKYEKRTNRPSSVISGEAKINRMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVAKREAL
LIVSASGGARMQESTYSLMQMAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGDLIIAEPGAMIGFAGPRVIKQT
IGADLPEGFQTAEFLLEHGLIDMIVHRKDLKKTLSDLIAMMTHKTSKIF

Sequences:

>Translated_289_residues
MGFADFFKNFKINKLRTAPSKEEQPSHWVKCPKCYALMYHKEVFSKYSVCLKCHYHFRMKAAERIEFLCDVGSFEEFDKH
LRPNDPLNFVDKESYKQRIKKYEKRTNRPSSVISGEAKINRMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVAKREAL
LIVSASGGARMQESTYSLMQMAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGDLIIAEPGAMIGFAGPRVIKQT
IGADLPEGFQTAEFLLEHGLIDMIVHRKDLKKTLSDLIAMMTHKTSKIF
>Mature_288_residues
GFADFFKNFKINKLRTAPSKEEQPSHWVKCPKCYALMYHKEVFSKYSVCLKCHYHFRMKAAERIEFLCDVGSFEEFDKHL
RPNDPLNFVDKESYKQRIKKYEKRTNRPSSVISGEAKINRMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVAKREALL
IVSASGGARMQESTYSLMQMAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGDLIIAEPGAMIGFAGPRVIKQTI
GADLPEGFQTAEFLLEHGLIDMIVHRKDLKKTLSDLIAMMTHKTSKIF

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1788655, Length=256, Percent_Identity=49.21875, Blast_Score=258, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI25147362, Length=185, Percent_Identity=28.1081081081081, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25147359, Length=185, Percent_Identity=28.1081081081081, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 32553; Mature: 32422

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFADFFKNFKINKLRTAPSKEEQPSHWVKCPKCYALMYHKEVFSKYSVCLKCHYHFRMK
CCHHHHHHCCCCCCEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAERIEFLCDVGSFEEFDKHLRPNDPLNFVDKESYKQRIKKYEKRTNRPSSVISGEAKIN
HHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCHHCC
RMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVAKREALLIVSASGGARMQESTYSLMQ
CCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHH
MAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGDLIIAEPGAMIGFAGPRVIKQT
HHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
IGADLPEGFQTAEFLLEHGLIDMIVHRKDLKKTLSDLIAMMTHKTSKIF
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GFADFFKNFKINKLRTAPSKEEQPSHWVKCPKCYALMYHKEVFSKYSVCLKCHYHFRMK
CHHHHHHCCCCCCEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAERIEFLCDVGSFEEFDKHLRPNDPLNFVDKESYKQRIKKYEKRTNRPSSVISGEAKIN
HHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCHHCC
RMPLQIVVFDFSFMGGSLGSVEGEKIVRAINRAVAKREALLIVSASGGARMQESTYSLMQ
CCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHH
MAKTSAALNRLSEAKLPFISLLSDPTYGGVSASFAFLGDLIIAEPGAMIGFAGPRVIKQT
HHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
IGADLPEGFQTAEFLLEHGLIDMIVHRKDLKKTLSDLIAMMTHKTSKIF
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]