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Identifier: 15645482

GI number: 15645482

Start: 915210

End: 916838

Strand: Reverse

Name: Not Available

Synonym: HP0863

Alternate gene names: 15645482

Gene position: 916838-915210 (Counterclockwise)

Preceding gene: 15645483

Following gene: 15645481

Centisome position: 54.97

GC content: 37.51

Gene sequence:

>1629_bases
ATGAATAAACCATTTTTAATCTTACTCATAGCCCTAATTGTCTTTAGCGGCTGTAACATGAGAAAATATTTCAAACCCGC
TAAACACCAAATTAAAGGCGAAGCGTATTTCCCTAACCATTTGCAAGAAAGTATCGTTTCGTCTAATCGTTATGGAGCCA
TTTTGAAAAATGGAGCGGTTATAGGCGATAAAGGTTTAACGCAGCTAAGAATCGGTAAGAACTTCAATTACGAAAGCAGT
TTTTTAAATGAGAGTCAAGGGTTTTTTATTCTTGCGCAAGATTGTTTGAACAAGATTGATAAAAAAACAAACAAAAGCAA
GGTGGCTAAGACTGAAGAAACGGAATTGAAATTAAAGGGCGTTGAAGCGGAAGTCCAAGATAAAGTCTGTCATCAAGTGG
AATTGATTAGCAATAACCCTAACGCCAGCCAACAATCTATCGTTATTCCTTTGGAGACTTTTGCCTTGAGCGCAAGCGTT
AAAGGGAATCTTTTAGCGGTGGTGTTAGCGGACAATTCAGCGAACTTATACGACATCACTTCTCAAAAATTGCTTTTTAG
TGAGAAAGGTTCCCCAAGCACCACGATCAATTCTTTAATGGCGATGCCTATTTTTATGGATACGGTCGTGGTGTTCCCCA
TGCTAGATGGGCGCTTGTTGGTCGTGGATTATGTGCACGGAAACCCTACGCCTATTAGAAACATTGTTATCAGCAGCGAT
AAGTTTTTTAACAATATCACCTACCTTATCGTAGATGGCAATAACATGATCGCTTCTACAGGGAAAAGGATACTCTCAGT
AGTGAGCGGTCAAGAGTTCAACTATGATGGGGATATTGTGGATTTGCTTTATGATAAGGGGACTTTATATGTGCTCACGC
TAGACGGGCAGATTTTGCAAATGGATAAGAGTTTGAGGGAATTAAACAGCGTGAAACTGCCTTCGTCGCTCAACACGATT
GTATTAAACCATAATAAATTGTATTCTTTAGAAAAACGAGGGTATGTGATAGAGGTGGATTTAAATGATTTTGATTCGTA
TAATGTCTATAAAACGCCAACTATAGGCAGTTTTAAGTTTTTTTCATCTAATCGTTTGGATAAAGGGGTGTTTTATGATA
AAAATCGGGTGTATTACGATCGCTACTATTTAGATTATAACGATTTTAAACCAAAACTTTATCCCGTTGTGGAAAAATCG
GCATCTAAAAAATCTCAAAAAGGCGAAAAAGGGAACGCTCCTATTTATTTGCAAGAAAGGCATAAAGCTAAAGAAAATAA
ACAGCCTTTAGAAGAAAACAAAGTTAAACCAAGAAATAGCGGGTTTGAAGAAGAAGAGGTTAAAACCAGAAGGCCTGAGC
CTATTAGGGATCAAAATAACGCCACCCAACAAGGCGAAACAAAAAACAATGAAAGTAAAAACGCTCCTGTCTTAAAAGAA
AACGCCGCTAAAAAAGAAGTGCCAAAACCAAATTCTAAAGAAGAAAAACGCCGCTTGAAAGAAGAAAAGAAAAAAGCCAA
AGCCGAACAAAGAGCGAGAGAATTTGAACAAAGAGCGAGAGAGCATCAAGAAAGAGATGAAAAAGAGCTTGAAGAAAGAA
GAAAAGCTTTAGAAATGAATAAGAAGTAG

Upstream 100 bases:

>100_bases
TCTGTTTTAAAACATTATGGAATGTTAGAAGATATTCAGCAAAACCCTTCCAAACCAACCAATCTAAAGAAAGAAACCAT
TCAAGGAACGCATTGATTTG

Downstream 100 bases:

>100_bases
GCCTATGCCAGCTAGGCAATCTTTTACAGATTTGAAAAACCTGGTTTTGTGCGATATAGGCAACACGCGTATCCATTTTG
CACAAAACTATCAGCTCTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAVIGDKGLTQLRIGKNFNYESS
FLNESQGFFILAQDCLNKIDKKTNKSKVAKTEETELKLKGVEAEVQDKVCHQVELISNNPNASQQSIVIPLETFALSASV
KGNLLAVVLADNSANLYDITSQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSD
KFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQMDKSLRELNSVKLPSSLNTI
VLNHNKLYSLEKRGYVIEVDLNDFDSYNVYKTPTIGSFKFFSSNRLDKGVFYDKNRVYYDRYYLDYNDFKPKLYPVVEKS
ASKKSQKGEKGNAPIYLQERHKAKENKQPLEENKVKPRNSGFEEEEVKTRRPEPIRDQNNATQQGETKNNESKNAPVLKE
NAAKKEVPKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEMNKK

Sequences:

>Translated_542_residues
MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAVIGDKGLTQLRIGKNFNYESS
FLNESQGFFILAQDCLNKIDKKTNKSKVAKTEETELKLKGVEAEVQDKVCHQVELISNNPNASQQSIVIPLETFALSASV
KGNLLAVVLADNSANLYDITSQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSD
KFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQMDKSLRELNSVKLPSSLNTI
VLNHNKLYSLEKRGYVIEVDLNDFDSYNVYKTPTIGSFKFFSSNRLDKGVFYDKNRVYYDRYYLDYNDFKPKLYPVVEKS
ASKKSQKGEKGNAPIYLQERHKAKENKQPLEENKVKPRNSGFEEEEVKTRRPEPIRDQNNATQQGETKNNESKNAPVLKE
NAAKKEVPKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEMNKK
>Mature_542_residues
MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAVIGDKGLTQLRIGKNFNYESS
FLNESQGFFILAQDCLNKIDKKTNKSKVAKTEETELKLKGVEAEVQDKVCHQVELISNNPNASQQSIVIPLETFALSASV
KGNLLAVVLADNSANLYDITSQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSD
KFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQMDKSLRELNSVKLPSSLNTI
VLNHNKLYSLEKRGYVIEVDLNDFDSYNVYKTPTIGSFKFFSSNRLDKGVFYDKNRVYYDRYYLDYNDFKPKLYPVVEKS
ASKKSQKGEKGNAPIYLQERHKAKENKQPLEENKVKPRNSGFEEEEVKTRRPEPIRDQNNATQQGETKNNESKNAPVLKE
NAAKKEVPKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEMNKK

Specific function: Binds plasminogen, specifically, and in a concentration and lysine-dependent manner. Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin. Acquisition of plasminogen/plasmin could enable H.py

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface (Probable). Note=The plasminogen-binding region is localized on the surface the bacterium (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PGBB_HELPY (O25534)

Other databases:

- EMBL:   AE000511
- PIR:   G64627
- RefSeq:   NP_207657.1
- GeneID:   899392
- GenomeReviews:   AE000511_GR
- KEGG:   hpy:HP0863
- NMPDR:   fig|85962.1.peg.854
- TIGR:   HP_0863
- HOGENOM:   HBG501845
- OMA:   NNMIAST
- ProtClustDB:   CLSK872461
- InterPro:   IPR015943
- InterPro:   IPR011046
- Gene3D:   G3DSA:2.130.10.10

Pfam domain/function: SSF50978 WD40_like

EC number: NA

Molecular weight: Translated: 61900; Mature: 61900

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAV
CCCCHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCCCCHHHHHHHHCCCCCCEEEECCEE
IGDKGLTQLRIGKNFNYESSFLNESQGFFILAQDCLNKIDKKTNKSKVAKTEETELKLKG
ECCCCCEEEEECCCCCCCHHHCCCCCCEEEEHHHHHHHHHHHCCHHHCCCCCCCEEEEEC
VEAEVQDKVCHQVELISNNPNASQQSIVIPLETFALSASVKGNLLAVVLADNSANLYDIT
CCHHHHHHHHHEEEEECCCCCCCCCEEEEEEHHEEEEEECCCCEEEEEEECCCCCEEEEC
SQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSD
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEECCC
KFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQ
CCCCCEEEEEECCCCEEHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEECCHHHH
MDKSLRELNSVKLPSSLNTIVLNHNKLYSLEKRGYVIEVDLNDFDSYNVYKTPTIGSFKF
HHHHHHHHHCCCCCCCCCEEEEECCEEEEECCCCEEEEEECCCCCCCCCEECCCCCCEEE
FSSNRLDKGVFYDKNRVYYDRYYLDYNDFKPKLYPVVEKSASKKSQKGEKGNAPIYLQER
CCCCCCCCCEEECCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEHH
HKAKENKQPLEENKVKPRNSGFEEEEVKTRRPEPIRDQNNATQQGETKNNESKNAPVLKE
HHCHHCCCCCHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHC
NAAKKEVPKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEMN
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KK
CC
>Mature Secondary Structure
MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAV
CCCCHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCCCCHHHHHHHHCCCCCCEEEECCEE
IGDKGLTQLRIGKNFNYESSFLNESQGFFILAQDCLNKIDKKTNKSKVAKTEETELKLKG
ECCCCCEEEEECCCCCCCHHHCCCCCCEEEEHHHHHHHHHHHCCHHHCCCCCCCEEEEEC
VEAEVQDKVCHQVELISNNPNASQQSIVIPLETFALSASVKGNLLAVVLADNSANLYDIT
CCHHHHHHHHHEEEEECCCCCCCCCEEEEEEHHEEEEEECCCCEEEEEEECCCCCEEEEC
SQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSD
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEECCC
KFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQ
CCCCCEEEEEECCCCEEHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEECCHHHH
MDKSLRELNSVKLPSSLNTIVLNHNKLYSLEKRGYVIEVDLNDFDSYNVYKTPTIGSFKF
HHHHHHHHHCCCCCCCCCEEEEECCEEEEECCCCEEEEEECCCCCCCCCEECCCCCCEEE
FSSNRLDKGVFYDKNRVYYDRYYLDYNDFKPKLYPVVEKSASKKSQKGEKGNAPIYLQER
CCCCCCCCCEEECCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEHH
HKAKENKQPLEENKVKPRNSGFEEEEVKTRRPEPIRDQNNATQQGETKNNESKNAPVLKE
HHCHHCCCCCHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHC
NAAKKEVPKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEMN
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9252185