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Identifier: 15645479

GI number: 15645479

Start: 913292

End: 913813

Strand: Reverse

Name: Not Available

Synonym: HP0860

Alternate gene names: 15645479

Gene position: 913813-913292 (Counterclockwise)

Preceding gene: 15645480

Following gene: 15645478

Centisome position: 54.79

GC content: 36.59

Gene sequence:

>522_bases
ATGAACACTAACAAAGCCCTTTTTTTGGACAGAGACGGCATTATCAATATTGATAAAGGCTATGTGAGTCAAAAAGAAGA
TTTTGAGTTTCAAAAAGGGATTTTTGAATTGCTAAAGCATGCGAAATCTTTAGGCTACAAACTGCTTTTAATCACCAACC
AATCTGGGATCAACCGAGGCTATTACACCCTTAAAGATTTTGAACAACTCACCCAATACCTCCAAGAAAGCTTGTTCAAA
GAATTAGGTTTTAATCTGGATGGCATCTATTTTTGCAGGCACGCCCCAGAAGAAAATTGCGCTTGCAGGAAGCCAAAGCC
TTCTTTGATTTTGCAAGCTGCTAAAGAGCATCAAATTTGCTTGGAGCAATCTTTTATGATAGGCGATAAAGAGAGCGACA
TGTTAGCCGGCTTGAACGCTAAAGTTAAAAATAACCTTTTGCTCATTCAAAACCCTTTAAAAACTCCTCATTCTTGGATA
CAATGTAAAGATTTTAAAGAGATGATAGATCTAATCAAATAA

Upstream 100 bases:

>100_bases
ATCCTTTATATGGGGATCATGCTCATTAACCACAAAATGCCTCATGCCATGCATCATCAAAACAACACCACTCAGCATGA
TCATAAAGGAGTGCATTCGC

Downstream 100 bases:

>100_bases
GGACAAGAATGCGTTATATTGATGATGAATTAGAAAATCAAACGATTTTAATCACCGGTGGGGCTGGCTTTGTAGGCAGT
AATCTAGCCTTTTATTTTCA

Product: hypothetical protein

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MNTNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLKHAKSLGYKLLLITNQSGINRGYYTLKDFEQLTQYLQESLFK
ELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQICLEQSFMIGDKESDMLAGLNAKVKNNLLLIQNPLKTPHSWI
QCKDFKEMIDLIK

Sequences:

>Translated_173_residues
MNTNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLKHAKSLGYKLLLITNQSGINRGYYTLKDFEQLTQYLQESLFK
ELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQICLEQSFMIGDKESDMLAGLNAKVKNNLLLIQNPLKTPHSWI
QCKDFKEMIDLIK
>Mature_173_residues
MNTNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLKHAKSLGYKLLLITNQSGINRGYYTLKDFEQLTQYLQESLFK
ELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQICLEQSFMIGDKESDMLAGLNAKVKNNLLLIQNPLKTPHSWI
QCKDFKEMIDLIK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=160, Percent_Identity=40.625, Blast_Score=134, Evalue=2e-33,
Organism=Escherichia coli, GI87082027, Length=136, Percent_Identity=34.5588235294118, Blast_Score=77, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 19994; Mature: 19994

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLKHAKSLGYKLLLITNQSGINRG
CCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCC
YYTLKDFEQLTQYLQESLFKELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQIC
CEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
LEQSFMIGDKESDMLAGLNAKVKNNLLLIQNPLKTPHSWIQCKDFKEMIDLIK
HHHHHHCCCCCCHHHHCCCCHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNTNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLKHAKSLGYKLLLITNQSGINRG
CCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCC
YYTLKDFEQLTQYLQESLFKELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQIC
CEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
LEQSFMIGDKESDMLAGLNAKVKNNLLLIQNPLKTPHSWIQCKDFKEMIDLIK
HHHHHHCCCCCCHHHHCCCCHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 12101286 [H]