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Identifier: 15645363

GI number: 15645363

Start: 797791

End: 798936

Strand: Reverse

Name: Not Available

Synonym: HP0743

Alternate gene names: 15645363

Gene position: 798936-797791 (Counterclockwise)

Preceding gene: 15645379

Following gene: 15645356

Centisome position: 47.9

GC content: 39.88

Gene sequence:

>1146_bases
ATGGCATTAGACAAAAGGATTTGGATGCATTTTGATCTTTTGCCTTTTGTGTTTATTATTCCCTTGTTGGTGGTTTCTTT
TTTGTTGATTTTTGAGAGCAGCGCGGTTTTGAGCTTGAAGCAAGGGGTTTATTATGCGATAGGGTTTATTCTCTTTTGGA
TCGTGTTTTTTATCCCTTTCAGAAAGCTCGGTCGTTGGCTGTTTGTGTTTTATTGGGCGTGCGTTATTTTATTGGCGTTA
GTGGATTTTATGGGATATAGTAAGCTTGGGGCGCAACGATGGCTAGTCATTCCCTTTATCTCTATCACTTTACAGCCTAG
CGAACCCGTGAAAATCGCCATTCTTTTATTGTTGGCGCATTTGATCAAAATCAACCCACCTCCTTTTAAGGGCTATGATT
GGGGCATGTTTTTAAAGCTTAGTTTTTACATTTGCTTACCGGCGGCTTTAATTTTAAAACAGCCTGATTTAGGCACGGCC
CTTATTGTGCTGATCATGGGTTTTGGGATTTTATTGATCGTAGGTTTAAGGACTAGGGTGTGGCTCCCTCTTTTTATCGC
TCTTTTAGTGGCTTCGCCTATCGCTTATCATTTTTTGCATGATTACCAAAAAAAACGCATCGCAGACTTTCTTTCTGAAA
AGCCTAATTACCATGTCATGCAATCCATCATCGCTATAGGATCGGGTGGGTTTTTAGGCAAATCTAAAGAAGCTTGTACC
CAAACCAAATTCAAATTCTTGCCTATCGCAACGAGCGATTTTATCTTTGCTTACTTCGTGGAGCGTTTTGGGTTTTTAGG
GGCTATGTTGCTTTTTGCAATTTATATAGGCTTGAGTTTGCATTTATTTTTTTATCTGTTTGAGAGCAACAGCGATTGGT
TTTTAAAGATTGTAGCCCTTGGGATCTCTATTTTAATCTTTGTTTATTCCAGCGTGAATATCGCCATGACTTTAGGGTTA
GCCCCTGTGGTGGGGATTCCCTTGCCATTATTTAGCTATGGAGGGAGCAGTTTTATCACTTTTATGATCCTGTTTGGGAT
CTTAGAAAACCTGCTTGCTTTTCGCTATATTTTTGGATACAATAGCAAACCATCCTTTGGGAATTTTGGATTCTTAGCTC
AGCTGGTCAGAGCACTCGGCTCATAA

Upstream 100 bases:

>100_bases
GATGAAGTTGGCATGATAACTTCTCTCTTTAAGGAGAATTATCTCAACTTGGATACAATCAAGAAATTAACACAATAAGA
TTAGGGGTTATGAAAAACGC

Downstream 100 bases:

>100_bases
CCGATTGGTCGTAGGTTCAAGTCCTACAGAATCCACCACTCCCGCTTTTTTATTCCCTTTTTAAGTGAAAAGCGATTGGA
CGCTTTCGTTATGATAAATC

Product: rod shape-determining protein (mreB)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MALDKRIWMHFDLLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFILFWIVFFIPFRKLGRWLFVFYWACVILLAL
VDFMGYSKLGAQRWLVIPFISITLQPSEPVKIAILLLLAHLIKINPPPFKGYDWGMFLKLSFYICLPAALILKQPDLGTA
LIVLIMGFGILLIVGLRTRVWLPLFIALLVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSKEACT
QTKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYLFESNSDWFLKIVALGISILIFVYSSVNIAMTLGL
APVVGIPLPLFSYGGSSFITFMILFGILENLLAFRYIFGYNSKPSFGNFGFLAQLVRALGS

Sequences:

>Translated_381_residues
MALDKRIWMHFDLLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFILFWIVFFIPFRKLGRWLFVFYWACVILLAL
VDFMGYSKLGAQRWLVIPFISITLQPSEPVKIAILLLLAHLIKINPPPFKGYDWGMFLKLSFYICLPAALILKQPDLGTA
LIVLIMGFGILLIVGLRTRVWLPLFIALLVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSKEACT
QTKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYLFESNSDWFLKIVALGISILIFVYSSVNIAMTLGL
APVVGIPLPLFSYGGSSFITFMILFGILENLLAFRYIFGYNSKPSFGNFGFLAQLVRALGS
>Mature_380_residues
ALDKRIWMHFDLLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFILFWIVFFIPFRKLGRWLFVFYWACVILLALV
DFMGYSKLGAQRWLVIPFISITLQPSEPVKIAILLLLAHLIKINPPPFKGYDWGMFLKLSFYICLPAALILKQPDLGTAL
IVLIMGFGILLIVGLRTRVWLPLFIALLVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSKEACTQ
TKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYLFESNSDWFLKIVALGISILIFVYSSVNIAMTLGLA
PVVGIPLPLFSYGGSSFITFMILFGILENLLAFRYIFGYNSKPSFGNFGFLAQLVRALGS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=326, Percent_Identity=38.6503067484663, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786277, Length=317, Percent_Identity=29.6529968454259, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43137; Mature: 43006

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDKRIWMHFDLLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFILFWIVFFIPF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLGRWLFVFYWACVILLALVDFMGYSKLGAQRWLVIPFISITLQPSEPVKIAILLLLAH
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHHHHH
LIKINPPPFKGYDWGMFLKLSFYICLPAALILKQPDLGTALIVLIMGFGILLIVGLRTRV
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WLPLFIALLVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSKEACT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHH
QTKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYLFESNSDWFLKIVAL
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GISILIFVYSSVNIAMTLGLAPVVGIPLPLFSYGGSSFITFMILFGILENLLAFRYIFGY
HHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
NSKPSFGNFGFLAQLVRALGS
CCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ALDKRIWMHFDLLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFILFWIVFFIPF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RKLGRWLFVFYWACVILLALVDFMGYSKLGAQRWLVIPFISITLQPSEPVKIAILLLLAH
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHHHHH
LIKINPPPFKGYDWGMFLKLSFYICLPAALILKQPDLGTALIVLIMGFGILLIVGLRTRV
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WLPLFIALLVASPIAYHFLHDYQKKRIADFLSEKPNYHVMQSIIAIGSGGFLGKSKEACT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHH
QTKFKFLPIATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYLFESNSDWFLKIVAL
HCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GISILIFVYSSVNIAMTLGLAPVVGIPLPLFSYGGSSFITFMILFGILENLLAFRYIFGY
HHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
NSKPSFGNFGFLAQLVRALGS
CCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]