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Identifier: 15645379

GI number: 15645379

Start: 814054

End: 815442

Strand: Reverse

Name: Not Available

Synonym: HP0760

Alternate gene names: NA

Gene position: 815442-814054 (Counterclockwise)

Preceding gene: 15645380

Following gene: 15645363

Centisome position: 48.89

GC content: 42.98

Gene sequence:

>1389_bases
ATGCAAATTGCAACAGCAATATGGAAAACAAGAATTTGGCAACTCCAAACCCATTTTGATAAAAAAGAAGCGCATTTGAA
GCATTTAGAAGCACAACACAAAGAATTTGTAAGAGATGAAAAACGCTATTTAGAAAAGGAAAAAAAAGAGCTTGAAAAAG
AACGCCAAATTTTAGAACAAGAAAAAGAAAATTTTAAAAAACAGCGCGCTGTTTGTAAAGAATCTCAAGCCAAAGCGCTA
GACGCGATGCTCAATTACATGGCTTATACTAAAGATGAAATTAAAAGCATGATTTTAGAGCAATTAGAAGAAGAATTAGA
AGCCCAAAAAAGCGCCTTAATCAGGCGTTATGAAAAAGAAGCCAAAGAAGAGGGCAAGAAAAAATCGTATGCCATTTTAG
CGGAAGCGACAGCCCGTTTTGCGGGTAATTATGCGGCAGAGAATTTAACAACTCGTATTGCTTTGCCTTGCTCAGATTAT
ATCGGTCGTGTGATAGGCAAAGACGGGAAAAATATTGAAGCGTTTAAAAAGGTCAGCGGGGTGGATATAGAATTTAGCGA
AGATAGCAGCGAATTGTGTTTGTCCAGTTTCAATCTTTATCGGCGTGAAGTAGCGAGCGAGACGCTTAAAATTTTAATAG
AAGACGGCCGTATCCAGCCTAACAGGATTGAAGAGGTTTATCATAGAGTCGCGCGCAACCTGGAAAAAGAATTGCTTTCT
GAAGGGGAGAGCGTGGTGTTAGAATTAGAGCTTGGAGCTATGGAAGATGAGCTTAAAATTTTAATAGGCAAAATGCGTTA
TCGCTCCAGTTTTGGGCAAAACGCCTTACAGCATTCTAAAGAAGTCGCTCTTTTAGCCGGCTTGATTGCAGAGCAGCTTG
GGGGGGATAAAAAACTCGCTAGAAGAGCCGGTATTTTGCATGATATTGGTAAAGCGCTCACCCAAGAGCTTGGGAGAGAT
CATGTGAATTTAGGGGTTGAGGTGTGCAAGCGCCATAAAGAAGATCCGGTTGTGATCAATGCGATTTATGCCCACCATGG
GCATGAAGAGATTTTGAGCGTGGAGTGCGCGAGCGTGTGCGCGGCTGATGCGCTTTCAGCAGGGCGTCCTGGGGCTAGGA
GAAAGAGCGATGAAGAATACGCTAAACGCATGCAAGCTTTAGAAGAGATCGCGCTAGAATTTGATGGGGTGGAAAAAGCG
TATGCGATGGAGAGTGGGCGAGAATTAAGAGTGATTGTCAAATCCAACCAAGTCAGGGACAATCAAGTGCCTATTATTGC
CAGAAAGATCGCTAAAAAGATAGAAGAGAGCGCTCAGTATGTGGGCGAAGTGGGCGTGCAAGTGGTGCGAGAAAGCCGTT
TCAAAACGACCGCTACGCTCAAGCAATAA

Upstream 100 bases:

>100_bases
GGCAAGCCACTTTAAAAAGCGCTTCAGCTAAAGCCAAATTGATGGAGTTTCAAGCGAAATCTTTTGTGGAAGCTGAAGAG
ATACGCATGAAAAGCCAAGA

Downstream 100 bases:

>100_bases
TCAAGCCTTTTTCCCGCACCTTTTCCAAATGCCTTTAGAAAAAACTTTATAATAGATGAATGAGCGCAAAAAAGTTTCTG
ATGCGATCACTACAAAAATA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MQIATAIWKTRIWQLQTHFDKKEAHLKHLEAQHKEFVRDEKRYLEKEKKELEKERQILEQEKENFKKQRAVCKESQAKAL
DAMLNYMAYTKDEIKSMILEQLEEELEAQKSALIRRYEKEAKEEGKKKSYAILAEATARFAGNYAAENLTTRIALPCSDY
IGRVIGKDGKNIEAFKKVSGVDIEFSEDSSELCLSSFNLYRREVASETLKILIEDGRIQPNRIEEVYHRVARNLEKELLS
EGESVVLELELGAMEDELKILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGRD
HVNLGVEVCKRHKEDPVVINAIYAHHGHEEILSVECASVCAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKA
YAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQYVGEVGVQVVRESRFKTTATLKQ

Sequences:

>Translated_462_residues
MQIATAIWKTRIWQLQTHFDKKEAHLKHLEAQHKEFVRDEKRYLEKEKKELEKERQILEQEKENFKKQRAVCKESQAKAL
DAMLNYMAYTKDEIKSMILEQLEEELEAQKSALIRRYEKEAKEEGKKKSYAILAEATARFAGNYAAENLTTRIALPCSDY
IGRVIGKDGKNIEAFKKVSGVDIEFSEDSSELCLSSFNLYRREVASETLKILIEDGRIQPNRIEEVYHRVARNLEKELLS
EGESVVLELELGAMEDELKILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGRD
HVNLGVEVCKRHKEDPVVINAIYAHHGHEEILSVECASVCAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKA
YAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQYVGEVGVQVVRESRFKTTATLKQ
>Mature_462_residues
MQIATAIWKTRIWQLQTHFDKKEAHLKHLEAQHKEFVRDEKRYLEKEKKELEKERQILEQEKENFKKQRAVCKESQAKAL
DAMLNYMAYTKDEIKSMILEQLEEELEAQKSALIRRYEKEAKEEGKKKSYAILAEATARFAGNYAAENLTTRIALPCSDY
IGRVIGKDGKNIEAFKKVSGVDIEFSEDSSELCLSSFNLYRREVASETLKILIEDGRIQPNRIEEVYHRVARNLEKELLS
EGESVVLELELGAMEDELKILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQLGGDKKLARRAGILHDIGKALTQELGRD
HVNLGVEVCKRHKEDPVVINAIYAHHGHEEILSVECASVCAADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKA
YAMESGRELRVIVKSNQVRDNQVPIIARKIAKKIEESAQYVGEVGVQVVRESRFKTTATLKQ

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA [H]

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675 [H]

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1 [H]

EC number: =3.1.4.16 [H]

Molecular weight: Translated: 52583; Mature: 52583

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIATAIWKTRIWQLQTHFDKKEAHLKHLEAQHKEFVRDEKRYLEKEKKELEKERQILEQ
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKENFKKQRAVCKESQAKALDAMLNYMAYTKDEIKSMILEQLEEELEAQKSALIRRYEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKEEGKKKSYAILAEATARFAGNYAAENLTTRIALPCSDYIGRVIGKDGKNIEAFKKVSG
HHHCCCHHHHHHHHHHHHHHHCCHHHHCCHHEEECCHHHHHHHHHCCCCCCHHHHHHHCC
VDIEFSEDSSELCLSSFNLYRREVASETLKILIEDGRIQPNRIEEVYHRVARNLEKELLS
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
EGESVVLELELGAMEDELKILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQLGGDKKLA
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RRAGILHDIGKALTQELGRDHVNLGVEVCKRHKEDPVVINAIYAHHGHEEILSVECASVC
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHCCHHHHHHHHHHHHH
AADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKAYAMESGRELRVIVKSNQVRD
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCC
NQVPIIARKIAKKIEESAQYVGEVGVQVVRESRFKTTATLKQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQIATAIWKTRIWQLQTHFDKKEAHLKHLEAQHKEFVRDEKRYLEKEKKELEKERQILEQ
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKENFKKQRAVCKESQAKALDAMLNYMAYTKDEIKSMILEQLEEELEAQKSALIRRYEKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKEEGKKKSYAILAEATARFAGNYAAENLTTRIALPCSDYIGRVIGKDGKNIEAFKKVSG
HHHCCCHHHHHHHHHHHHHHHCCHHHHCCHHEEECCHHHHHHHHHCCCCCCHHHHHHHCC
VDIEFSEDSSELCLSSFNLYRREVASETLKILIEDGRIQPNRIEEVYHRVARNLEKELLS
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
EGESVVLELELGAMEDELKILIGKMRYRSSFGQNALQHSKEVALLAGLIAEQLGGDKKLA
CCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RRAGILHDIGKALTQELGRDHVNLGVEVCKRHKEDPVVINAIYAHHGHEEILSVECASVC
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEHHHHCCHHHHHHHHHHHHH
AADALSAGRPGARRKSDEEYAKRMQALEEIALEFDGVEKAYAMESGRELRVIVKSNQVRD
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEEECCCCCC
NQVPIIARKIAKKIEESAQYVGEVGVQVVRESRFKTTATLKQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA