| Definition | Helicobacter pylori 26695, complete genome. |
|---|---|
| Accession | NC_000915 |
| Length | 1,667,867 |
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The map label for this gene is uvrA
Identifier: 15645328
GI number: 15645328
Start: 757282
End: 760089
Strand: Reverse
Name: uvrA
Synonym: HP0705
Alternate gene names: 15645328
Gene position: 760089-757282 (Counterclockwise)
Preceding gene: 15645336
Following gene: 15645310
Centisome position: 45.57
GC content: 40.31
Gene sequence:
>2808_bases ATGGATAAGATCATTATTCAAGGGGCTAGGGAAAACAATCTCAAAAATATTTTTTTAGAAATCCCTAAAAACCAGTTTGT TGTTTTTACCGGATTGAGCGGTTCGGGTAAATCCACTTTAGCGTTTGACACTTTATACGCTGAAGGCCAAAGGCGCTATT TAGAGAGTTTGTCCAGCTATGCTAGGCAATTTTTAGACAAAGTGGGTAAGCCTAATGTGGATAAAATTGAAGGCCTAACC CCTGCGATCGCTATTGATCAAAAAACCACTTCTAAAAACCCCAGATCCACTGTGGGGACGATCACTGAAATTTATGATTA TTTAAGGTTGTTGTTTGCAAGGGTTGGGGAGCAATTTTGCCCCACATGTTTAGAGCCTATTAGTTCTATGAGCACGAGCG ATATTATTTCTCAAATCTGTCATTTAGAAGAAAATTCTAAAATCATTATTCTCGCCCCCATTATTAAAGATAAAAAAGGT TCGTTTAATGATAAATTAGAGAGCTTGCGTTTGAAGGGGTATGTGAGGGCTTTTGTTGATGGGGTGATGGTGCGTTTAGA TGAAGAAATCCATTTGCACAAAACCAAAAAACACACCATTGAAGCGGTGGTGGATAGGGTGGTAGTTAATAATGAAAACG CTTCACGGATCGCTAGCGCAATAGAAAAAGCCCTTAAAGAAAGCTATGGGGAATTAGAAGTGGAAATCTTGCAAGACAAC GCGCCAAGCATCAGAAAGCATTACAGCGAACATAAGGCATGCTTTAAATGCAAGATGAGTTTTGAAGAATTAGAGCCTTT GAGTTTTTCCTTCAATTCGCCTAAAGGGGCGTGCGAAAGTTGCTTGGGTTTGGGGACAAAATTTAGCCTAGATATTAGTA AGATTTTAGATCCTAACACGCCTTTAAATCAAGGAGCGATTAAAGTGATTTTTGGGTATAACCGCAGTTATTACGCTCAA ATGTTTGAAGGTTTTTGCGAATATAATGGCATTGACAGTGCACTTTGTTTTAACGAATTGAATAAAGAGCAGCAAGACGC TCTTTTGTATGGGAATGGCACTGAAATCAGCTTTCATTTTAAAAACAGCCCTTTAAAACGCCCTTGGAAAGGCATCATTC AAATCGCTTATGACATGTTTAAAGAGCAAAAGGATTTGAGCGATTACATGAGCGAAAAAACCTGTTCTTCGTGCGAGGGG CATCGTTTGAAAGCCTCCAGTTTGAGCGTCCAAGTCGCTGGCTTGAAAATGGCGGATTTTTTAACTAAGCCCATTGAAGA AGTTTATCACTTTTTTAATGATCCCACGCATTTTAGCTATCTTAACGAGCAAGAAAAAAAGATCGCTGAACCCATTTTAA AAGAGATTTTAGAAAGGGTGTTTTTTTTATACGATGTGGGGTTAGGGTATTTGACTTTAGGGAGGGATGCGCGAACGATT AGCGGAGGGGAGAGCCAAAGGATACGAATCGCTAGTCAAATCGGGAGTGGTTTGACAGGGGTTTTGTATGTTTTAGACGA GCCTAGCATTGGCTTGCATGAAAAAGATACGCTCAAACTCATTAACACCCTTAGGAATTTACAAAAAAAAGGGAACACGC TCATTGTCGTAGAGCATGACAAAGAGACGATTAAGCATGCGGATTTTGTTGTGGATATTGGGCCAAAGGCTGGAAGGCAT GGGGGTGAAGTGGTTTTTAGCGGGAGCGTGAAAGAATTATTGCAAAATAACCATTCTACCGCCTTGTATCTCAACGGCAC TAAAAAGATTGAGCGCCCTAAATTTGAACTCCCTAAAGAAAAGCATTTTTTAGAAATTAAAAATGTCAATATCAATAACA TTAAGAATTTGAGCGTTCAAATCCCTTTAAAACAATTGGTGTGCATTACTGGGGTGAGCGGGAGCGGTAAAAGCTCGTTG ATTTTACAAACCCTTTTACCCACCGCTCAAACCCTTTTAAACCATGCTAAAAAAACTCAAAGCTTGAATGGGGTGGAGAT TGTAGGGTTGGAGCATTTGGATAAAGTGATTTATTTAGATCAAGCCCCCATAGGCAAAACCCCACGAAGCAACCCTGCCA CTTACACGGGAGTGATGGATGAAATCAGGATTTTATTTGCCGAGCAAAAAGAAGCTAAAATTTTAGGCTATAGTGCGAGC CGTTTTAGCTTTAATGTTAAAGGAGGGCGGTGCGAGAAATGCCAAGGCGATGGGGACATTAAAATAGAAATGCACTTTTT GCCTGATGTGTTAGTCCAATGCGATAGCTGTAAGGGCGCTAAATACAACCCCCAAACTTTAGAAATCAAGGTGAAAGGCA AATCCATTGCCGATGTGTTGAACATGAGCGTGGAAGAGGCTTATGAATTTTTTGCTAAATTCCCTAAAATCGCCGTGAAG TTAAAAACGCTTATGGATGTGGGCTTAGGCTATATCACTTTAGGGCAAAACGCTACGACTTTAAGTGGGGGGGAGGCTCA AAGGATCAAATTAGCTAAAGAATTGAGTAAAAAAGACACAGGCAAAACCCTTTATATTTTAGATGAGCCTACTACCGGTT TGCATTTTGAAGACGTGAATCATCTTTTACAAGTCTTGCATTCTTTAGTGGCGTTAGGCAATTCTATGCTAGTGATTGAG CATAATTTAGACATTATCAAAAACGCTGACTACATTATAGACATGGGGCCTGATGGGGGGGATAAGGGCGGGAAAGTCAT TGCGAGCGGCACGCCTTTAGAGGTGGCGCAAAATTGCGAAAAAACCCAAAGCTACACGGGAAAATTTTTAGCTTTGGAAT TGAAATAG
Upstream 100 bases:
>100_bases TGAATAAGAAATGATAATAAAACCATTCTTTTTTGAAGTATAATAGCTCCTTTTAATCCATTTTCTTATTTTAAGGAAAC TCTTGCAACATAAAACCATT
Downstream 100 bases:
>100_bases CTTGCATTTGTTTGTAGAAACAATGTAGGGCTGAAAATAACAGACAGCTAAATATTAGAGAGCAGAGGCACTATTGCGTC ATGGTTTCAAAATTATAAGG
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 935; Mature: 935
Protein sequence:
>935_residues MDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSYARQFLDKVGKPNVDKIEGLT PAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARVGEQFCPTCLEPISSMSTSDIISQICHLEENSKIIILAPIIKDKKG SFNDKLESLRLKGYVRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVVNNENASRIASAIEKALKESYGELEVEILQDN APSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNTPLNQGAIKVIFGYNRSYYAQ MFEGFCEYNGIDSALCFNELNKEQQDALLYGNGTEISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKTCSSCEG HRLKASSLSVQVAGLKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLGRDARTI SGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHDKETIKHADFVVDIGPKAGRH GGEVVFSGSVKELLQNNHSTALYLNGTKKIERPKFELPKEKHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSGSGKSSL ILQTLLPTAQTLLNHAKKTQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKILGYSAS RFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGKSIADVLNMSVEEAYEFFAKFPKIAVK LKTLMDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGNSMLVIE HNLDIIKNADYIIDMGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK
Sequences:
>Translated_935_residues MDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSYARQFLDKVGKPNVDKIEGLT PAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARVGEQFCPTCLEPISSMSTSDIISQICHLEENSKIIILAPIIKDKKG SFNDKLESLRLKGYVRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVVNNENASRIASAIEKALKESYGELEVEILQDN APSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNTPLNQGAIKVIFGYNRSYYAQ MFEGFCEYNGIDSALCFNELNKEQQDALLYGNGTEISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKTCSSCEG HRLKASSLSVQVAGLKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLGRDARTI SGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHDKETIKHADFVVDIGPKAGRH GGEVVFSGSVKELLQNNHSTALYLNGTKKIERPKFELPKEKHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSGSGKSSL ILQTLLPTAQTLLNHAKKTQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKILGYSAS RFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGKSIADVLNMSVEEAYEFFAKFPKIAVK LKTLMDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGNSMLVIE HNLDIIKNADYIIDMGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK >Mature_935_residues MDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSYARQFLDKVGKPNVDKIEGLT PAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARVGEQFCPTCLEPISSMSTSDIISQICHLEENSKIIILAPIIKDKKG SFNDKLESLRLKGYVRAFVDGVMVRLDEEIHLHKTKKHTIEAVVDRVVVNNENASRIASAIEKALKESYGELEVEILQDN APSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNTPLNQGAIKVIFGYNRSYYAQ MFEGFCEYNGIDSALCFNELNKEQQDALLYGNGTEISFHFKNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKTCSSCEG HRLKASSLSVQVAGLKMADFLTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLGRDARTI SGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHDKETIKHADFVVDIGPKAGRH GGEVVFSGSVKELLQNNHSTALYLNGTKKIERPKFELPKEKHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSGSGKSSL ILQTLLPTAQTLLNHAKKTQSLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKILGYSAS RFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGKSIADVLNMSVEEAYEFFAKFPKIAVK LKTLMDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDTGKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGNSMLVIE HNLDIIKNADYIIDMGPDGGDKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=947, Percent_Identity=51.636747624076, Blast_Score=912, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 104062; Mature: 104062
Theoretical pI: Translated: 7.55; Mature: 7.55
Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSY CCCEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHH ARQFLDKVGKPNVDKIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARVGEQFC HHHHHHHHCCCCCHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHC PTCLEPISSMSTSDIISQICHLEENSKIIILAPIIKDKKGSFNDKLESLRLKGYVRAFVD HHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH GVMVRLDEEIHLHKTKKHTIEAVVDRVVVNNENASRIASAIEKALKESYGELEVEILQDN HHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECC APSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNT CCHHHHHHHHHHHHHHEECCHHHCCCCEEECCCCCHHHHHHHCCCCEEEEEHHHHCCCCC PLNQGAIKVIFGYNRSYYAQMFEGFCEYNGIDSALCFNELNKEQQDALLYGNGTEISFHF CCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCCEEEEEE KNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKTCSSCEGHRLKASSLSVQVAGLKMADF CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCHHHHH LTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLGRDARTI HHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC SGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHD CCCCCCEEEEHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC KETIKHADFVVDIGPKAGRHGGEVVFSGSVKELLQNNHSTALYLNGTKKIERPKFELPKE HHHHHHCCEEEECCCCCCCCCCCEEECCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCC KHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSGSGKSSLILQTLLPTAQTLLNHAKKTQ CCEEEEECCCCCCCCCEEEEECHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHC SLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKILGYSAS CCCCEEEEEHHHHCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEEEECC RFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGKSIADVL EEEEECCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHH NMSVEEAYEFFAKFPKIAVKLKTLMDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDT CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCC GKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGNSMLVIEHNLDIIKNADYIIDMGPDGG CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCEEEEECCCCC DKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEC >Mature Secondary Structure MDKIIIQGARENNLKNIFLEIPKNQFVVFTGLSGSGKSTLAFDTLYAEGQRRYLESLSSY CCCEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHH ARQFLDKVGKPNVDKIEGLTPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLFARVGEQFC HHHHHHHHCCCCCHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHC PTCLEPISSMSTSDIISQICHLEENSKIIILAPIIKDKKGSFNDKLESLRLKGYVRAFVD HHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH GVMVRLDEEIHLHKTKKHTIEAVVDRVVVNNENASRIASAIEKALKESYGELEVEILQDN HHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECC APSIRKHYSEHKACFKCKMSFEELEPLSFSFNSPKGACESCLGLGTKFSLDISKILDPNT CCHHHHHHHHHHHHHHEECCHHHCCCCEEECCCCCHHHHHHHCCCCEEEEEHHHHCCCCC PLNQGAIKVIFGYNRSYYAQMFEGFCEYNGIDSALCFNELNKEQQDALLYGNGTEISFHF CCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEECCCEEEEEE KNSPLKRPWKGIIQIAYDMFKEQKDLSDYMSEKTCSSCEGHRLKASSLSVQVAGLKMADF CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEECCHHHHH LTKPIEEVYHFFNDPTHFSYLNEQEKKIAEPILKEILERVFFLYDVGLGYLTLGRDARTI HHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC SGGESQRIRIASQIGSGLTGVLYVLDEPSIGLHEKDTLKLINTLRNLQKKGNTLIVVEHD CCCCCCEEEEHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC KETIKHADFVVDIGPKAGRHGGEVVFSGSVKELLQNNHSTALYLNGTKKIERPKFELPKE HHHHHHCCEEEECCCCCCCCCCCEEECCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCC KHFLEIKNVNINNIKNLSVQIPLKQLVCITGVSGSGKSSLILQTLLPTAQTLLNHAKKTQ CCEEEEECCCCCCCCCEEEEECHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHC SLNGVEIVGLEHLDKVIYLDQAPIGKTPRSNPATYTGVMDEIRILFAEQKEAKILGYSAS CCCCEEEEEHHHHCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCEEEEEECC RFSFNVKGGRCEKCQGDGDIKIEMHFLPDVLVQCDSCKGAKYNPQTLEIKVKGKSIADVL EEEEECCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHH NMSVEEAYEFFAKFPKIAVKLKTLMDVGLGYITLGQNATTLSGGEAQRIKLAKELSKKDT CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCC GKTLYILDEPTTGLHFEDVNHLLQVLHSLVALGNSMLVIEHNLDIIKNADYIIDMGPDGG CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCEEEEECCCCC DKGGKVIASGTPLEVAQNCEKTQSYTGKFLALELK CCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9923682 [H]