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Identifier: 15645263

GI number: 15645263

Start: 685734

End: 686414

Strand: Reverse

Name: Not Available

Synonym: HP0639

Alternate gene names: 15645263

Gene position: 686414-685734 (Counterclockwise)

Preceding gene: 15645275

Following gene: 15645261

Centisome position: 41.16

GC content: 38.47

Gene sequence:

>681_bases
ATGGAACAAAAAATTTGCGTGATCGGTTTTAGCGGCGGGCAAGACAGCACCACTTTAGCCGTGTGGGCGAAAAAGCGTTT
TAAAAAAGTCTGTTTAGTGGGGTTTGATTATGCGCAAAAACACTCTGTGGAATTAGAATGCGCTCAAAAAATCGCTTCTC
TTTTACAACTCCCTTATGAAATCATCCCATTAGATTTTTTAGAAAATATCACCCGCTCTGCGCTTTTTAAAAACTCTAAC
GATTTAATAGGGCATTCGCATGCGCAAAATAAAGATTTACCCAATTCTTTTGTGCCTAATCGTAACGCTATTTTTATCAC
CCTTTTGCATTCTTACGCGCAAAAACTAGGGGCTAGCAATATCGCTTTAGGAGTTTCGCAAGCGGATTTTAGCGGCTATC
CGGATTGTAAAGAAGATTTTATTAAAAGCATCGAGCATGCCTTAAATTTAGGATCAAACACGGCGATTAAAATCCTAACG
CCTTTAATGTTTTTGAATAAAGCGCAAGAATTTCAAATGGCTAAAGATTTGGGCGTCTTGGATTTAGTCATCAAAGAAAC
GCACACCTGCTATCAAGGAGAGCGAAAGATTTTGCATGCTTATGGTTATGGTTGCGATAAATGCCCGGCATGCCAATTGA
GAAAAAAAGGCTTTGAAGAGTTTCAAGCTAATAAAAAATAA

Upstream 100 bases:

>100_bases
TCAAACAATTCTTTTAATCCTTCTTCTAACTCAAACACGCTTTTTACTCTTAAAATTTCTTTGTGTTATTATATCTTTTT
AGAATTTTTAAGGAATTTTG

Downstream 100 bases:

>100_bases
GGTTTTTTAAAAAACCAACTAAAGAGCGGTAAAAAGCGTGTTTTAATGTTTGTTTTTAAAGTTATATGTATAGTTAAGAT
AAACGCTCACCACTCTTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MEQKICVIGFSGGQDSTTLAVWAKKRFKKVCLVGFDYAQKHSVELECAQKIASLLQLPYEIIPLDFLENITRSALFKNSN
DLIGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKLGASNIALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILT
PLMFLNKAQEFQMAKDLGVLDLVIKETHTCYQGERKILHAYGYGCDKCPACQLRKKGFEEFQANKK

Sequences:

>Translated_226_residues
MEQKICVIGFSGGQDSTTLAVWAKKRFKKVCLVGFDYAQKHSVELECAQKIASLLQLPYEIIPLDFLENITRSALFKNSN
DLIGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKLGASNIALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILT
PLMFLNKAQEFQMAKDLGVLDLVIKETHTCYQGERKILHAYGYGCDKCPACQLRKKGFEEFQANKK
>Mature_226_residues
MEQKICVIGFSGGQDSTTLAVWAKKRFKKVCLVGFDYAQKHSVELECAQKIASLLQLPYEIIPLDFLENITRSALFKNSN
DLIGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKLGASNIALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILT
PLMFLNKAQEFQMAKDLGVLDLVIKETHTCYQGERKILHAYGYGCDKCPACQLRKKGFEEFQANKK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=223, Percent_Identity=39.0134529147982, Blast_Score=167, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25278; Mature: 25278

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQKICVIGFSGGQDSTTLAVWAKKRFKKVCLVGFDYAQKHSVELECAQKIASLLQLPYE
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCHH
IIPLDFLENITRSALFKNSNDLIGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKLGASN
HCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCC
IALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILTPLMFLNKAQEFQMAKDLGVL
CEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
DLVIKETHTCYQGERKILHAYGYGCDKCPACQLRKKGFEEFQANKK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHCCCC
>Mature Secondary Structure
MEQKICVIGFSGGQDSTTLAVWAKKRFKKVCLVGFDYAQKHSVELECAQKIASLLQLPYE
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCHH
IIPLDFLENITRSALFKNSNDLIGHSHAQNKDLPNSFVPNRNAIFITLLHSYAQKLGASN
HCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCC
IALGVSQADFSGYPDCKEDFIKSIEHALNLGSNTAIKILTPLMFLNKAQEFQMAKDLGVL
CEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
DLVIKETHTCYQGERKILHAYGYGCDKCPACQLRKKGFEEFQANKK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA