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Identifier: 15645245

GI number: 15645245

Start: 666410

End: 668698

Strand: Reverse

Name: Not Available

Synonym: HP0621

Alternate gene names: 15645245

Gene position: 668698-666410 (Counterclockwise)

Preceding gene: 15645246

Following gene: 15645240

Centisome position: 40.09

GC content: 38.49

Gene sequence:

>2289_bases
TTGTCAGACGCTCCAAAAAGATCCCTTAATCCAACCCTAATGATGAATAATAATAATACCCCACCCAAACCCCTAGAAGA
AAGCCTGGATTTAAAAGAGTTTATCGCTCTTTTTAAAACCTTTTTTGCCAAAGAAAGAGATACTATTGCTTTAGAAAACG
ATCTCAAGCAAACTTTCACTTATTTAAACGAAGTGGATGCGATCGGTTTGCCCACCCCTAAAAGCGTGAAAGAAAGCGAT
CTTATTATCATCAAACTCACCAAATTAGGGACGCTCCATTTAGATGAAATTTTTGAGATTGTCAAACGATTGCACTACAT
TGTCGTTTTACAAAACGCTTTTAAAACTTTCACGCATTTAAAATTTCATGAACGCCTTAACGCTATTGTCCTGCCCCCTT
TTTTTAACGATCTGATCGCTTTATTTGATGATGAAGGGAAAATCAAACAAGGGGCTAACGCTACCCTAGACGCTTTGAAT
GAAAGTTTGAACCGCCTTAAAAAAGAGAGCGTAAAAATCATTCACCATTACGCCCGCTCTAAAGAGCTTGCCCCTTATTT
AGTGGATACGCAAAGCCATCTTAAGCATGGTTATGAATGCCTTTTATTGAAAAGCGGGTTTTCTGGCGCGATTAAAGGCG
TTGTGCTAGAAAGGAGCGCTAATGGCTATTTCTATCTTTTGCCTGAAAGCGCCCAAAAAATCGCCCAAAAAATCGCCCAA
ATTGGTAATGAAATAGATTGTTGCATTGTTGAAATGTGCCAAACTCTAAGCCATAGCTTGCAAAAACACCTTTTATTTTT
AAAATTCCTTTTTAAAGAATTTGATTTTTTAGACAGCTTGCAAGCCCGGCTTAATTTCGCTAAAGCCTACAATTTAGAAT
TTGTCATGCCAAGCTTTACACAAAAAAAAATGATTTTAGAAAACTTTTCACACCCCATTTTAAAAGAGCCAAAGCCCTTA
AATTTGAAGTTTGAAAAATCCATGCTTGCTGTTACCGGCGTGAATGCGGGCGGGAAAACCATGCTCTTAAAATCGCTTTT
AAGCGCGGCTTTTTTAAGCAAGCATCTCATTCCTATGAAAATCAACGCCCATCATTCCATTATCCCCTATTTTAAAGAAA
TCCACGCCATTATTAATGACCCCCAAAACAGCGCGAACAATATCTCTACTTTTGCCGGCAGAATGAAGCAATTTAGCGCT
CTTTTATCCAAAGAAAACATGCTTTTAGGCGTTGATGAAATAGAGCTAGGGACTGACGCTGATGAAGCGAGCAGTTTGTA
TAAAACCCTGTTAGAAAAATTGCTTAAACAAAACAACCAAATCATTATCACCACGCACCACAAACGCTTGAGCGTGTTAA
TGGCAGAAAACAAGGAAGTGGAATTACTAGCCGCTCTTTATGATGAAGAAAAAGAACGGCCCACTTACACTTTTTTAAAA
GGGGTTATTGGCAAAAGCTATGCGTTTGAAACCGCTTTGCGCTATGGCGTGCCGCATTTTTTGATTGAAAAAGCGAAAAC
CTTCTATGGCGAAGATAAGGAAAAATTGAATGTTTTGATTGAAAATTCCAGCGCGCTAGAAAGGGAATTGAAACAAAAGA
ATGAACATTTAGAGAACGCTTTAAAAGAGCAAGAATATTTGAAAAACGCATGGCTTTTAGAAATGGAAAAACAAAAAGAA
ATCTTTCACAATAAAAAATTGGAATTGGAAAAATCCTACCAACAAGCCCTAAATATCTTAAAAAGCGAAGTCGCTTCAAA
AGATACTAGCTCCATGCATAAAGAAATCCATAAAGCGAGCGAAATTTTAAGCAAACACAAAACAAACCAAGAGATCCCAC
AAATCATAACGAACTTTCAAGCCAACGAAAAAGCGCGCTACAAGAATGAAAGCGTGCTGATTGTACAAATTTTAGACAAG
GGCTATTATTGGATAGAAACCGAGCTTGGCATGCGTTTAAAAGCGCATGGGAGTTTGTTGAAAAAAATCCAAAAACCCCC
TAAAAACAAATTCAAACCCCCTAAAACAACCATTCCTAAACCTAAAGAAGCGAGCTTGCGCCTTGATTTAAGGGGGCAAC
GCAGCGAAGAAGCCCTGGATTTACTAGACGCTTTTTTAAACGACGCGCTTTTAGGGGGCTTTGAAGAAGTGCTGATTTGC
CACGGCAAAGGGAGCGGGATTTTAGAAAAGTTTGTGAAAGAATTTTTAAAAAACCACCCCAAAGTGGTGAGCTTTAGCGA
CGCTCCCATTAATTTAGGCGGCAGTGGGGTTAAAATCGTTAAATTGTAG

Upstream 100 bases:

>100_bases
TTAAAGTCAATAACCAAACCTTTAATTTAGTGAGCGGAACTTTAAGCTTTTTAGGCAAAAAACAAACCCCTATGAAAGAC
GTTCTTGTGGATTTGGATTC

Downstream 100 bases:

>100_bases
TTTTTGGCACTTTTTATGGGGAATACAAAAATCCGCTTTAAACTATAAAGCCATTTCACACCAACACCCAATGAGAACAA
AGCCTTTTAAAAGAGCGTTA

Product: recombination and DNA strand exchange inhibitor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MSDAPKRSLNPTLMMNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPKSVKESD
LIIIKLTKLGTLHLDEIFEIVKRLHYIVVLQNAFKTFTHLKFHERLNAIVLPPFFNDLIALFDDEGKIKQGANATLDALN
ESLNRLKKESVKIIHHYARSKELAPYLVDTQSHLKHGYECLLLKSGFSGAIKGVVLERSANGYFYLLPESAQKIAQKIAQ
IGNEIDCCIVEMCQTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMILENFSHPILKEPKPL
NLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSA
LLSKENMLLGVDEIELGTDADEASSLYKTLLEKLLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLK
GVIGKSYAFETALRYGVPHFLIEKAKTFYGEDKEKLNVLIENSSALERELKQKNEHLENALKEQEYLKNAWLLEMEKQKE
IFHNKKLELEKSYQQALNILKSEVASKDTSSMHKEIHKASEILSKHKTNQEIPQIITNFQANEKARYKNESVLIVQILDK
GYYWIETELGMRLKAHGSLLKKIQKPPKNKFKPPKTTIPKPKEASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLIC
HGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL

Sequences:

>Translated_762_residues
MSDAPKRSLNPTLMMNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPKSVKESD
LIIIKLTKLGTLHLDEIFEIVKRLHYIVVLQNAFKTFTHLKFHERLNAIVLPPFFNDLIALFDDEGKIKQGANATLDALN
ESLNRLKKESVKIIHHYARSKELAPYLVDTQSHLKHGYECLLLKSGFSGAIKGVVLERSANGYFYLLPESAQKIAQKIAQ
IGNEIDCCIVEMCQTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMILENFSHPILKEPKPL
NLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSA
LLSKENMLLGVDEIELGTDADEASSLYKTLLEKLLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLK
GVIGKSYAFETALRYGVPHFLIEKAKTFYGEDKEKLNVLIENSSALERELKQKNEHLENALKEQEYLKNAWLLEMEKQKE
IFHNKKLELEKSYQQALNILKSEVASKDTSSMHKEIHKASEILSKHKTNQEIPQIITNFQANEKARYKNESVLIVQILDK
GYYWIETELGMRLKAHGSLLKKIQKPPKNKFKPPKTTIPKPKEASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLIC
HGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL
>Mature_761_residues
SDAPKRSLNPTLMMNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFTYLNEVDAIGLPTPKSVKESDL
IIIKLTKLGTLHLDEIFEIVKRLHYIVVLQNAFKTFTHLKFHERLNAIVLPPFFNDLIALFDDEGKIKQGANATLDALNE
SLNRLKKESVKIIHHYARSKELAPYLVDTQSHLKHGYECLLLKSGFSGAIKGVVLERSANGYFYLLPESAQKIAQKIAQI
GNEIDCCIVEMCQTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMILENFSHPILKEPKPLN
LKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMKINAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSAL
LSKENMLLGVDEIELGTDADEASSLYKTLLEKLLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLKG
VIGKSYAFETALRYGVPHFLIEKAKTFYGEDKEKLNVLIENSSALERELKQKNEHLENALKEQEYLKNAWLLEMEKQKEI
FHNKKLELEKSYQQALNILKSEVASKDTSSMHKEIHKASEILSKHKTNQEIPQIITNFQANEKARYKNESVLIVQILDKG
YYWIETELGMRLKAHGSLLKKIQKPPKNKFKPPKTTIPKPKEASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLICH
GKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL

Specific function: This Protein Is Involved In The Repair Of Mismatches In DNA. It Is Possible That It Carries Out The Mismatch Recognition Step. This Protein Has A Weak Atpase Activity. [C]

COG id: COG1193

COG function: function code L; Mismatch repair ATPase (MutS family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Smr domain [H]

Homologues:

Organism=Escherichia coli, GI1789089, Length=257, Percent_Identity=27.6264591439689, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005747
- InterPro:   IPR000432
- InterPro:   IPR007696
- InterPro:   IPR002625 [H]

Pfam domain/function: PF00488 MutS_V; PF01713 Smr [H]

EC number: NA

Molecular weight: Translated: 86754; Mature: 86623

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50828 SMR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAPKRSLNPTLMMNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFT
CCCCCCCCCCCEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
YLNEVDAIGLPTPKSVKESDLIIIKLTKLGTLHLDEIFEIVKRLHYIVVLQNAFKTFTHL
HHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFHERLNAIVLPPFFNDLIALFDDEGKIKQGANATLDALNESLNRLKKESVKIIHHYARS
HHHHHCCEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KELAPYLVDTQSHLKHGYECLLLKSGFSGAIKGVVLERSANGYFYLLPESAQKIAQKIAQ
CCCCCCEECCHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHH
IGNEIDCCIVEMCQTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFT
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHH
QKKMILENFSHPILKEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMK
HHHHHHHHCCCCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEE
INAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIELGTDA
ECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCEECCCCH
DEASSLYKTLLEKLLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLK
HHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHH
GVIGKSYAFETALRYGVPHFLIEKAKTFYGEDKEKLNVLIENSSALERELKQKNEHLENA
HHHCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHH
LKEQEYLKNAWLLEMEKQKEIFHNKKLELEKSYQQALNILKSEVASKDTSSMHKEIHKAS
HHHHHHHHHHHHEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EILSKHKTNQEIPQIITNFQANEKARYKNESVLIVQILDKGYYWIETELGMRLKAHGSLL
HHHHHHCCCHHHHHHHHCCCCCCHHHCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHH
KKIQKPPKNKFKPPKTTIPKPKEASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLIC
HHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
HGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL
ECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SDAPKRSLNPTLMMNNNNTPPKPLEESLDLKEFIALFKTFFAKERDTIALENDLKQTFT
CCCCCCCCCCEEEECCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHH
YLNEVDAIGLPTPKSVKESDLIIIKLTKLGTLHLDEIFEIVKRLHYIVVLQNAFKTFTHL
HHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFHERLNAIVLPPFFNDLIALFDDEGKIKQGANATLDALNESLNRLKKESVKIIHHYARS
HHHHHCCEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KELAPYLVDTQSHLKHGYECLLLKSGFSGAIKGVVLERSANGYFYLLPESAQKIAQKIAQ
CCCCCCEECCHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHH
IGNEIDCCIVEMCQTLSHSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFT
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHH
QKKMILENFSHPILKEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMK
HHHHHHHHCCCCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEE
INAHHSIIPYFKEIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIELGTDA
ECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCEECCCCH
DEASSLYKTLLEKLLKQNNQIIITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLK
HHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHHH
GVIGKSYAFETALRYGVPHFLIEKAKTFYGEDKEKLNVLIENSSALERELKQKNEHLENA
HHHCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHH
LKEQEYLKNAWLLEMEKQKEIFHNKKLELEKSYQQALNILKSEVASKDTSSMHKEIHKAS
HHHHHHHHHHHHEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EILSKHKTNQEIPQIITNFQANEKARYKNESVLIVQILDKGYYWIETELGMRLKAHGSLL
HHHHHHCCCHHHHHHHHCCCCCCHHHCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHH
KKIQKPPKNKFKPPKTTIPKPKEASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLIC
HHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
HGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL
ECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]