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Identifier: 15644685

GI number: 15644685

Start: 53715

End: 56186

Strand: Reverse

Name: Not Available

Synonym: HP0054

Alternate gene names: 15644685

Gene position: 56186-53715 (Counterclockwise)

Preceding gene: 15644686

Following gene: 15644684

Centisome position: 3.37

GC content: 32.93

Gene sequence:

>2472_bases
ATGCTCTTTGATCAAACCTTAACCTATATTTCTTTATTTTCTGGGGCAGGAGTGGGGTGCTATGGGCTTTTAGAAGAGGG
GTTTGAATGCGTTGCTACCAATGAAATTTTAGAAAAACGCTTGAATATCCAAAGGATTAATCGCAAATGCAAATTAGATG
AAAGCTACATTAGTGGGGACATTAAAAAGCCAGAAACAAAAGAAAAAATTTTAAAGCAAATTGAATTTTATTCTAAAAAA
TTTGGTAATGATAGGGTTGATTTAGTGGTAGCAACCCCACCTTGTCAAGGCATGAGCGTAGCCAATCATAAGAAGAAAAA
CGATGAGATCAAACGGAATTCTTTGGTGGTTGAAAGCATTGATTTGATCAAACAAATCAAACCCAGATTTTTTATTTTAG
AAAATGTCCCTAGTTTTTATAAAACAGGTTGTATAGACAAAAATGATAATTTGCTAGAAATAGGATCTATGATAGAGCAA
AATTTGAGTGGCGATTATATGCTCTATGATGAGGTAATCAATTTTAAAAATTTTGGAGCTAATTCAAGCCGAACAAGAAC
TTTAGTGATAGGGGTTTGTAAAGAGTTTAAAGATTTTATAAGCGCGTTAGAATTTTTTCCTGATTTCAAACAAGAAAAAA
CCTTAAAAGAAGTGATAGGATCGTTAAAACCACTTGCTTGGGGCGAGTATGACAACACGGATTTTTATCATAGTTTTAGA
ACTTATCCAAAGCATATGCAAGAATGGATTAAGGATTTAAAAGAAGGACAAAGCGCGTTTGAGAATACAGAATTAAACAA
AAAACCTCATAGAATTGTTGGCAGTAAGATTGTCTTAAATGTTTCTAAAAATGGCGATAAATATAAAAGACAAAAATATC
ATAGCGTTGCCCCTTGCATTCATACAAGAAACGACCAAATGGCTAGCCAAAACACGATCCACCCCAAAGATGATAGAGTG
TTTTCCATTAGAGAGCTGATGCTTTTAATGAATATCCCTAGCCGTTTTAAGTGGTTAGATTTAGAATTACAAGAATTAAA
CGCCCTTAACCAACAAGAAAAAGAAAAAATCTCCAAACAAAACGAAATGAATATAAGACAAAGCATCGGTGAAGCTGTTC
CAACGATTATTTTTAAGCAAATTGCCATAAAGATAAAAAATTTCATGTCTCAAACCCACTTAGAGCCTAAAGAAATCATT
AGGCTTATTGATGTGCACCATTTATTAGAGCCACAAAATTTGAAGCGATTTATTTTAGAAAATCAAAACAAGATTGCAAG
AGCGAGTTTAGTGAGTTTGGCAGAAATGTCTAATTCTAAACGCATAGAAAAAAGCGCGTATTTTACAAACCCTTTTATTA
TTAATGAAATAGCGAAGTTATTGCCAAGCTTTAAACAAGAGAGTGTTACTATTATAGAGCCAAGTGCAGGGTGTGGGAAT
TTCTTAAGTGCTCTTTTTAAAAAATACACTTCTGTTAAAAAAGTTTATTTAAAGTGTATAGATATTGATAAAAATAGTTT
AGAAATTTTAGAGATTTTATATAAAGATTGCATTCCTAACAATTTTGAGATGGAATTGATTTGCAAAGATTTTCTAGCCT
ATGAATGCGGCAAAGTGGATTTAATTGTGGGCAATCCGCCTTTTGGCAAAACGCATGAAAGATTCAAAGATTATAGTTTA
AGACTCACTCATTTAGCAGGGATTTTTTTAGAAAAGTCTTTAAAACTAGCCAACTTTACAGCGATGGTTATGCCTAAAAA
CCTTTTAAACACTAAAGAGTATGCAGAAACTAGAACTAAGCTTGAAAAAAAGGGAGTAGGAGCGATTTTAGACTTTGGCG
AGCTTGGTTTTAAGGGTGTTTTGGTAGAAACAATTGCTATTGTTACACAAAAATCAAAAGAAGTTTTAGCGCGTTCGTTA
CCCCTAAATCTAAGCATCAAGCAAAAGCCAAGCTATATTTTTGACAAACAATTGCCCTATTGGGTTATCTATCGCAACGC
TTTTTTTGATAAGGTGTTTCATTCCATGCAGTTTGGTCTTTTTGAAGTGTTTAGAGACAGACAAATCACTAATTCTGTGT
TGGTTAAAAATGGTATTCGTGTGATTAAATCTCGCAATATTGATGAAAACGGAAAGATTATTAGCATTGAAAATTACGAT
AGCTACATTCAAAAAGAGGTTTTAAGTCCGTTTAAGATAGCTTCATTTTTAGACAGAGATGATGTCTATTTAACCCCCAA
CATGACCTATAAGCCAAGGATTTTAAAAAAAGAAAAAGGCTATGTGGTTAATGGCTCTGTGGCTATTTTAATCCCTAAAA
ACCCCATATCTTTAAGCAAGAAACAATGCGATTATATCTCTAGCGTTGAATTTAGAGATTTTTATAAAATCGCTAGGAAT
TATCAAACGCGCACCTTAAATATTGATAGCATGAGTTGTTTTTGGTTTGGAATTTTAAGGAGTAGCTTATGA

Upstream 100 bases:

>100_bases
CGAACAGGCACTAAAGAGGCTTTTGAAACCATGCTTAAAGAAATTGAGAGCTTGAAACATTAATGCTTCAAATGAATTTG
GTTTAATCCTTAATCCCCTT

Downstream 100 bases:

>100_bases
AAGAGCAATCAATGATTGATTTTTTAAAACTTAGAGATTATGACATTAGAAAAACACAAAATGCGCGATGGATAGATCAA
AAATGCACCCCTGATGTGTT

Product: adenine/cytosine DNA methyltransferase

Products: NA

Alternate protein names: M.HgaIA; Cytosine-specific methyltransferase HgaIA; M.HgaI-1 [H]

Number of amino acids: Translated: 823; Mature: 823

Protein sequence:

>823_residues
MLFDQTLTYISLFSGAGVGCYGLLEEGFECVATNEILEKRLNIQRINRKCKLDESYISGDIKKPETKEKILKQIEFYSKK
FGNDRVDLVVATPPCQGMSVANHKKKNDEIKRNSLVVESIDLIKQIKPRFFILENVPSFYKTGCIDKNDNLLEIGSMIEQ
NLSGDYMLYDEVINFKNFGANSSRTRTLVIGVCKEFKDFISALEFFPDFKQEKTLKEVIGSLKPLAWGEYDNTDFYHSFR
TYPKHMQEWIKDLKEGQSAFENTELNKKPHRIVGSKIVLNVSKNGDKYKRQKYHSVAPCIHTRNDQMASQNTIHPKDDRV
FSIRELMLLMNIPSRFKWLDLELQELNALNQQEKEKISKQNEMNIRQSIGEAVPTIIFKQIAIKIKNFMSQTHLEPKEII
RLIDVHHLLEPQNLKRFILENQNKIARASLVSLAEMSNSKRIEKSAYFTNPFIINEIAKLLPSFKQESVTIIEPSAGCGN
FLSALFKKYTSVKKVYLKCIDIDKNSLEILEILYKDCIPNNFEMELICKDFLAYECGKVDLIVGNPPFGKTHERFKDYSL
RLTHLAGIFLEKSLKLANFTAMVMPKNLLNTKEYAETRTKLEKKGVGAILDFGELGFKGVLVETIAIVTQKSKEVLARSL
PLNLSIKQKPSYIFDKQLPYWVIYRNAFFDKVFHSMQFGLFEVFRDRQITNSVLVKNGIRVIKSRNIDENGKIISIENYD
SYIQKEVLSPFKIASFLDRDDVYLTPNMTYKPRILKKEKGYVVNGSVAILIPKNPISLSKKQCDYISSVEFRDFYKIARN
YQTRTLNIDSMSCFWFGILRSSL

Sequences:

>Translated_823_residues
MLFDQTLTYISLFSGAGVGCYGLLEEGFECVATNEILEKRLNIQRINRKCKLDESYISGDIKKPETKEKILKQIEFYSKK
FGNDRVDLVVATPPCQGMSVANHKKKNDEIKRNSLVVESIDLIKQIKPRFFILENVPSFYKTGCIDKNDNLLEIGSMIEQ
NLSGDYMLYDEVINFKNFGANSSRTRTLVIGVCKEFKDFISALEFFPDFKQEKTLKEVIGSLKPLAWGEYDNTDFYHSFR
TYPKHMQEWIKDLKEGQSAFENTELNKKPHRIVGSKIVLNVSKNGDKYKRQKYHSVAPCIHTRNDQMASQNTIHPKDDRV
FSIRELMLLMNIPSRFKWLDLELQELNALNQQEKEKISKQNEMNIRQSIGEAVPTIIFKQIAIKIKNFMSQTHLEPKEII
RLIDVHHLLEPQNLKRFILENQNKIARASLVSLAEMSNSKRIEKSAYFTNPFIINEIAKLLPSFKQESVTIIEPSAGCGN
FLSALFKKYTSVKKVYLKCIDIDKNSLEILEILYKDCIPNNFEMELICKDFLAYECGKVDLIVGNPPFGKTHERFKDYSL
RLTHLAGIFLEKSLKLANFTAMVMPKNLLNTKEYAETRTKLEKKGVGAILDFGELGFKGVLVETIAIVTQKSKEVLARSL
PLNLSIKQKPSYIFDKQLPYWVIYRNAFFDKVFHSMQFGLFEVFRDRQITNSVLVKNGIRVIKSRNIDENGKIISIENYD
SYIQKEVLSPFKIASFLDRDDVYLTPNMTYKPRILKKEKGYVVNGSVAILIPKNPISLSKKQCDYISSVEFRDFYKIARN
YQTRTLNIDSMSCFWFGILRSSL
>Mature_823_residues
MLFDQTLTYISLFSGAGVGCYGLLEEGFECVATNEILEKRLNIQRINRKCKLDESYISGDIKKPETKEKILKQIEFYSKK
FGNDRVDLVVATPPCQGMSVANHKKKNDEIKRNSLVVESIDLIKQIKPRFFILENVPSFYKTGCIDKNDNLLEIGSMIEQ
NLSGDYMLYDEVINFKNFGANSSRTRTLVIGVCKEFKDFISALEFFPDFKQEKTLKEVIGSLKPLAWGEYDNTDFYHSFR
TYPKHMQEWIKDLKEGQSAFENTELNKKPHRIVGSKIVLNVSKNGDKYKRQKYHSVAPCIHTRNDQMASQNTIHPKDDRV
FSIRELMLLMNIPSRFKWLDLELQELNALNQQEKEKISKQNEMNIRQSIGEAVPTIIFKQIAIKIKNFMSQTHLEPKEII
RLIDVHHLLEPQNLKRFILENQNKIARASLVSLAEMSNSKRIEKSAYFTNPFIINEIAKLLPSFKQESVTIIEPSAGCGN
FLSALFKKYTSVKKVYLKCIDIDKNSLEILEILYKDCIPNNFEMELICKDFLAYECGKVDLIVGNPPFGKTHERFKDYSL
RLTHLAGIFLEKSLKLANFTAMVMPKNLLNTKEYAETRTKLEKKGVGAILDFGELGFKGVLVETIAIVTQKSKEVLARSL
PLNLSIKQKPSYIFDKQLPYWVIYRNAFFDKVFHSMQFGLFEVFRDRQITNSVLVKNGIRVIKSRNIDENGKIISIENYD
SYIQKEVLSPFKIASFLDRDDVYLTPNMTYKPRILKKEKGYVVNGSVAILIPKNPISLSKKQCDYISSVEFRDFYKIARN
YQTRTLNIDSMSCFWFGILRSSL

Specific function: This methylase recognizes the strands carrying the 5'- GCGTC-3' sequence, causes specific methylation on C-2, and protects the DNA from cleavage by the HgaI endonuclease [H]

COG id: COG0827

COG function: function code L; Adenine-specific DNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C5-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018117
- InterPro:   IPR001525 [H]

Pfam domain/function: PF00145 DNA_methylase [H]

EC number: =2.1.1.37 [H]

Molecular weight: Translated: 95116; Mature: 95116

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00092 N6_MTASE ; PS00094 C5_MTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDQTLTYISLFSGAGVGCYGLLEEGFECVATNEILEKRLNIQRINRKCKLDESYISGD
CCCHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHCCC
IKKPETKEKILKQIEFYSKKFGNDRVDLVVATPPCQGMSVANHKKKNDEIKRNSLVVESI
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHH
DLIKQIKPRFFILENVPSFYKTGCIDKNDNLLEIGSMIEQNLSGDYMLYDEVINFKNFGA
HHHHHCCCCEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHCCCC
NSSRTRTLVIGVCKEFKDFISALEFFPDFKQEKTLKEVIGSLKPLAWGEYDNTDFYHSFR
CCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
TYPKHMQEWIKDLKEGQSAFENTELNKKPHRIVGSKIVLNVSKNGDKYKRQKYHSVAPCI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEECCEEEEEECCCCCHHHHHHHHHHCCHH
HTRNDQMASQNTIHPKDDRVFSIRELMLLMNIPSRFKWLDLELQELNALNQQEKEKISKQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHCCHHHHHHHHHH
NEMNIRQSIGEAVPTIIFKQIAIKIKNFMSQTHLEPKEIIRLIDVHHLLEPQNLKRFILE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHC
NQNKIARASLVSLAEMSNSKRIEKSAYFTNPFIINEIAKLLPSFKQESVTIIEPSAGCGN
CCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHH
FLSALFKKYTSVKKVYLKCIDIDKNSLEILEILYKDCIPNNFEMELICKDFLAYECGKVD
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEE
LIVGNPPFGKTHERFKDYSLRLTHLAGIFLEKSLKLANFTAMVMPKNLLNTKEYAETRTK
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEECCHHHHCHHHHHHHHHH
LEKKGVGAILDFGELGFKGVLVETIAIVTQKSKEVLARSLPLNLSIKQKPSYIFDKQLPY
HHHCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCE
WVIYRNAFFDKVFHSMQFGLFEVFRDRQITNSVLVKNGIRVIKSRNIDENGKIISIENYD
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHH
SYIQKEVLSPFKIASFLDRDDVYLTPNMTYKPRILKKEKGYVVNGSVAILIPKNPISLSK
HHHHHHHCCHHHHHHHCCCCCEEECCCCCCCCCCEECCCCEEECCEEEEEECCCCCCCCH
KQCDYISSVEFRDFYKIARNYQTRTLNIDSMSCFWFGILRSSL
HHHHHHHCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLFDQTLTYISLFSGAGVGCYGLLEEGFECVATNEILEKRLNIQRINRKCKLDESYISGD
CCCHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHCCC
IKKPETKEKILKQIEFYSKKFGNDRVDLVVATPPCQGMSVANHKKKNDEIKRNSLVVESI
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHCCCCCCHHHHHHHHHHHH
DLIKQIKPRFFILENVPSFYKTGCIDKNDNLLEIGSMIEQNLSGDYMLYDEVINFKNFGA
HHHHHCCCCEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHCCCC
NSSRTRTLVIGVCKEFKDFISALEFFPDFKQEKTLKEVIGSLKPLAWGEYDNTDFYHSFR
CCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
TYPKHMQEWIKDLKEGQSAFENTELNKKPHRIVGSKIVLNVSKNGDKYKRQKYHSVAPCI
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEECCEEEEEECCCCCHHHHHHHHHHCCHH
HTRNDQMASQNTIHPKDDRVFSIRELMLLMNIPSRFKWLDLELQELNALNQQEKEKISKQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHHHHCCHHHHHHHHHH
NEMNIRQSIGEAVPTIIFKQIAIKIKNFMSQTHLEPKEIIRLIDVHHLLEPQNLKRFILE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHC
NQNKIARASLVSLAEMSNSKRIEKSAYFTNPFIINEIAKLLPSFKQESVTIIEPSAGCGN
CCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHH
FLSALFKKYTSVKKVYLKCIDIDKNSLEILEILYKDCIPNNFEMELICKDFLAYECGKVD
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEE
LIVGNPPFGKTHERFKDYSLRLTHLAGIFLEKSLKLANFTAMVMPKNLLNTKEYAETRTK
EEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEECCHHHHCHHHHHHHHHH
LEKKGVGAILDFGELGFKGVLVETIAIVTQKSKEVLARSLPLNLSIKQKPSYIFDKQLPY
HHHCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCE
WVIYRNAFFDKVFHSMQFGLFEVFRDRQITNSVLVKNGIRVIKSRNIDENGKIISIENYD
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHH
SYIQKEVLSPFKIASFLDRDDVYLTPNMTYKPRILKKEKGYVVNGSVAILIPKNPISLSK
HHHHHHHCCHHHHHHHCCCCCEEECCCCCCCCCCEECCCCEEECCEEEEEECCCCCCCCH
KQCDYISSVEFRDFYKIARNYQTRTLNIDSMSCFWFGILRSSL
HHHHHHHCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1856224 [H]