Click here to switch to the map view.

The map label for this gene is mtlF

Identifier: 13508392

GI number: 13508392

Start: 778538

End: 778969

Strand: Direct

Name: mtlF

Synonym: MPN653

Alternate gene names: 13508392

Gene position: 778538-778969 (Clockwise)

Preceding gene: 13508391

Following gene: 13508394

Centisome position: 95.36

GC content: 30.09

Gene sequence:

>432_bases
GTGAAATTACTAAAAAATAACATTTACATTAACGTTTATTTAAAAAACAAACAAGAAATTTTTGAATTTGTTTTTAAAAA
GTTTAAAGAAGATGGTGCTGTACTAGATAGTTTTTTACCAGCAATTGTGGAACGCGATAAAGCAGCTAGTGTAGCAATTG
GTAATTACCTCTTTTTACCCCACCCAGTTTATGACGAAATAGCAAACATTCAAAAAGAAAAAATGGTGTTTATTGGTTTA
AAAGATGTAATTAACATTGATGGTCAACCAATTAAATTTATCTGTGGTTTAGCCTTAAAAGGTGAGCACCAAATGGATGC
GTTGCAATCTTTAGCAATAGCTTTTTCAGACCCTGAAGAAGTGGAAAAGTTAGTTAAAGATAAGGATTTAACACAAGATA
AGGTACTTGAATTTTTAGCAAAACACAACTAA

Upstream 100 bases:

>100_bases
CAAATTGCTAAATTAATAAATGAAAAAGCTTGAACAGAGTTAGCGAAATTATCCAGTTTAGAAGAGTCAGAATGAAACCT
AATTAAACAAGAATTAAGCC

Downstream 100 bases:

>100_bases
GCAGTCACAATATTACTTAATTAAAAATAGTAAGTAACTAAATAAATTAACTTGCTTTTCGTCAGTTTTGTAACTAATAT
AGTCATTTAAAAAATTTTAT

Product: PTS system mannitol-specific component IIA (EIIA-MTL)

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Mtl; EIII-Mtl; PTS system mannitol-specific EIIA component

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MKLLKNNIYINVYLKNKQEIFEFVFKKFKEDGAVLDSFLPAIVERDKAASVAIGNYLFLPHPVYDEIANIQKEKMVFIGL
KDVINIDGQPIKFICGLALKGEHQMDALQSLAIAFSDPEEVEKLVKDKDLTQDKVLEFLAKHN

Sequences:

>Translated_143_residues
MKLLKNNIYINVYLKNKQEIFEFVFKKFKEDGAVLDSFLPAIVERDKAASVAIGNYLFLPHPVYDEIANIQKEKMVFIGL
KDVINIDGQPIKFICGLALKGEHQMDALQSLAIAFSDPEEVEKLVKDKDLTQDKVLEFLAKHN
>Mature_143_residues
MKLLKNNIYINVYLKNKQEIFEFVFKKFKEDGAVLDSFLPAIVERDKAASVAIGNYLFLPHPVYDEIANIQKEKMVFIGL
KDVINIDGQPIKFICGLALKGEHQMDALQSLAIAFSDPEEVEKLVKDKDLTQDKVLEFLAKHN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG4668

COG function: function code G; Mannitol/fructose-specific phosphotransferase system, IIA domain

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTMA_MYCPN (P75145)

Other databases:

- EMBL:   U00089
- PIR:   S73515
- RefSeq:   NP_110342.1
- ProteinModelPortal:   P75145
- IntAct:   P75145
- GeneID:   877014
- GenomeReviews:   U00089_GR
- KEGG:   mpn:MPN653
- OMA:   ERTISTY
- ProtClustDB:   CLSK275473
- BioCyc:   MPNE272634:MPN653-MONOMER
- GO:   GO:0005737
- InterPro:   IPR016152
- InterPro:   IPR002178
- Gene3D:   G3DSA:3.40.930.10

Pfam domain/function: PF00359 PTS_EIIA_2; SSF55804 PTrfase/Anion_transptr

EC number: 2.7.1.69

Molecular weight: Translated: 16313; Mature: 16313

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS51094 PTS_EIIA_TYPE_2; PS00372 PTS_EIIA_TYPE_2_HIS

Important sites: ACT_SITE 61-61

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKNNIYINVYLKNKQEIFEFVFKKFKEDGAVLDSFLPAIVERDKAASVAIGNYLFLP
CCEECCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCEEECC
HPVYDEIANIQKEKMVFIGLKDVINIDGQPIKFICGLALKGEHQMDALQSLAIAFSDPEE
CCHHHHHHCCCHHHEEEEEHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCHHH
VEKLVKDKDLTQDKVLEFLAKHN
HHHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKLLKNNIYINVYLKNKQEIFEFVFKKFKEDGAVLDSFLPAIVERDKAASVAIGNYLFLP
CCEECCCEEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEECCEEECC
HPVYDEIANIQKEKMVFIGLKDVINIDGQPIKFICGLALKGEHQMDALQSLAIAFSDPEE
CCHHHHHHCCCHHHEEEEEHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCHHH
VEKLVKDKDLTQDKVLEFLAKHN
HHHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633