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The map label for this gene is mtlD [H]

Identifier: 13508391

GI number: 13508391

Start: 777463

End: 778557

Strand: Direct

Name: mtlD [H]

Synonym: MPN652

Alternate gene names: 13508391

Gene position: 777463-778557 (Clockwise)

Preceding gene: 13508390

Following gene: 13508392

Centisome position: 95.23

GC content: 29.5

Gene sequence:

>1095_bases
ATGAAAAGAATTAATGTATTGCACTTTGGCGCTGGTAATATAGGTAGAGGTGTTATATTACCGATTTACCAACAAAATGA
CTTTTCCATTGATTTAGTGGAATTGAATCAAAATACAGTTAATGAGTTACAAAAGCAAAAACAATACCAAGTTCATTACC
TTGATTGTGATCAAAGTCAGTTAGTTAATGACTTTAATACTTGAAACTTAAAGGATGAAGCGAAGATTATTGAACTAATG
GAAAGAGCTGATGTTATTTCCACTTCAATAGGTGCTAAAAACTTAGCTAGTTTAAAAACTTTGTTTGACAAAGCTAAGTT
CCATAAAAGGGCTATAGTGCTTTGCTTTGAAAACGGCTTTCGGATTAGTTCTAACTTTAAAAACATTTTGCAATTAAATA
ACACACAAGTAAATTTTGTGGATGTGGTAATCGATACAATTGCACCTAACTTCGAAAAGAAAGCGAATTTCTTGGATATT
TATTGCGAGAAGTATTCAGAAATTTATGCTGAAACTTTCCCGCTAGAAATTAAGGGAGTAAATCAAAAGAATAGTTTAGA
TAGATTCATTATTAAAAAACTTTTATTAGTCAATGCACTGCACAGTGTTATTGGACTTTTAGGCTTTCAACAAAAGCTTA
AGTATGTACATGAAACATTGCAAGTTAAAAGTAATTTGACTTTTGTAGAAAAATTAGCCCAACAAATTATTGATGCCCTT
TGTGCTGAATATCCTGAATTTAATAAAAATAATTTGTTAAGTTATGGCAAAAATAACTTAGTCCGTTTTGCTAATCCCAA
GATTCAAGATTTAAACACACGCTTAATTAGGGAACCATTACGTAAACTTAACCAAAATGAACGCTTTTATGCCATTTATA
AACTCTTTAAAAAGAATAAGATTGCACTAAATAATATTTTGCAAGTTTATCTGATGGTTTTAAAAACTAATATAACAGAT
GATACCGAAAGCCAACAAATTGCTAAATTAATAAATGAAAAAGCTTGAACAGAGTTAGCGAAATTATCCAGTTTAGAAGA
GTCAGAATGAAACCTAATTAAACAAGAATTAAGCCGTGAAATTACTAAAAAATAA

Upstream 100 bases:

>100_bases
TATGATCGCGTAAAAGCGAAGCGTGCAGACGCTACGATTTATACCATCAATCAGTTCTTAGATAAACAAGGCTATTTAAC
TATTATTGAAAAGATTAAAA

Downstream 100 bases:

>100_bases
CATTTACATTAACGTTTATTTAAAAAACAAACAAGAAATTTTTGAATTTGTTTTTAAAAAGTTTAAAGAAGATGGTGCTG
TACTAGATAGTTTTTTACCA

Product: mannitol-1-phosphate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKRINVLHFGAGNIGRGVILPIYQQNDFSIDLVELNQNTVNELQKQKQYQVHYLDCDQSQLVNDFNTWNLKDEAKIIELM
ERADVISTSIGAKNLASLKTLFDKAKFHKRAIVLCFENGFRISSNFKNILQLNNTQVNFVDVVIDTIAPNFEKKANFLDI
YCEKYSEIYAETFPLEIKGVNQKNSLDRFIIKKLLLVNALHSVIGLLGFQQKLKYVHETLQVKSNLTFVEKLAQQIIDAL
CAEYPEFNKNNLLSYGKNNLVRFANPKIQDLNTRLIREPLRKLNQNERFYAIYKLFKKNKIALNNILQVYLMVLKTNITD
DTESQQIAKLINEKAWTELAKLSSLEESEWNLIKQELSREITKK

Sequences:

>Translated_364_residues
MKRINVLHFGAGNIGRGVILPIYQQNDFSIDLVELNQNTVNELQKQKQYQVHYLDCDQSQLVNDFNT*NLKDEAKIIELM
ERADVISTSIGAKNLASLKTLFDKAKFHKRAIVLCFENGFRISSNFKNILQLNNTQVNFVDVVIDTIAPNFEKKANFLDI
YCEKYSEIYAETFPLEIKGVNQKNSLDRFIIKKLLLVNALHSVIGLLGFQQKLKYVHETLQVKSNLTFVEKLAQQIIDAL
CAEYPEFNKNNLLSYGKNNLVRFANPKIQDLNTRLIREPLRKLNQNERFYAIYKLFKKNKIALNNILQVYLMVLKTNITD
DTESQQIAKLINEKA*TELAKLSSLEESE*NLIKQELSREITKK
>Mature_364_residues
MKRINVLHFGAGNIGRGVILPIYQQNDFSIDLVELNQNTVNELQKQKQYQVHYLDCDQSQLVNDFNT*NLKDEAKIIELM
ERADVISTSIGAKNLASLKTLFDKAKFHKRAIVLCFENGFRISSNFKNILQLNNTQVNFVDVVIDTIAPNFEKKANFLDI
YCEKYSEIYAETFPLEIKGVNQKNSLDRFIIKKLLLVNALHSVIGLLGFQQKLKYVHETLQVKSNLTFVEKLAQQIIDAL
CAEYPEFNKNNLLSYGKNNLVRFANPKIQDLNTRLIREPLRKLNQNERFYAIYKLFKKNKIALNNILQVYLMVLKTNITD
DTESQQIAKLINEKA*TELAKLSSLEESE*NLIKQELSREITKK

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1790028, Length=386, Percent_Identity=25.6476683937824, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR023028
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.17 [H]

Molecular weight: Translated: 41659; Mature: 41659

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRINVLHFGAGNIGRGVILPIYQQNDFSIDLVELNQNTVNELQKQKQYQVHYLDCDQSQ
CCCEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHCCEEEEECCCHHH
LVNDFNTNLKDEAKIIELMERADVISTSIGAKNLASLKTLFDKAKFHKRAIVLCFENGFR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCE
ISSNFKNILQLNNTQVNFVDVVIDTIAPNFEKKANFLDIYCEKYSEIYAETFPLEIKGVN
EHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHCCEEEECCC
QKNSLDRFIIKKLLLVNALHSVIGLLGFQQKLKYVHETLQVKSNLTFVEKLAQQIIDALC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AEYPEFNKNNLLSYGKNNLVRFANPKIQDLNTRLIREPLRKLNQNERFYAIYKLFKKNKI
HCCCCCCCCCCHHCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCH
ALNNILQVYLMVLKTNITDDTESQQIAKLINEKATELAKLSSLEESENLIKQELSREITK
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
K
C
>Mature Secondary Structure
MKRINVLHFGAGNIGRGVILPIYQQNDFSIDLVELNQNTVNELQKQKQYQVHYLDCDQSQ
CCCEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHHHHHCCEEEEECCCHHH
LVNDFNTNLKDEAKIIELMERADVISTSIGAKNLASLKTLFDKAKFHKRAIVLCFENGFR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCE
ISSNFKNILQLNNTQVNFVDVVIDTIAPNFEKKANFLDIYCEKYSEIYAETFPLEIKGVN
EHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHHHHHCCEEEECCC
QKNSLDRFIIKKLLLVNALHSVIGLLGFQQKLKYVHETLQVKSNLTFVEKLAQQIIDALC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AEYPEFNKNNLLSYGKNNLVRFANPKIQDLNTRLIREPLRKLNQNERFYAIYKLFKKNKI
HCCCCCCCCCCHHCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCH
ALNNILQVYLMVLKTNITDDTESQQIAKLINEKATELAKLSSLEESENLIKQELSREITK
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]