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The map label for this gene is frr [H]

Identifier: 13508375

GI number: 13508375

Start: 762639

End: 763193

Strand: Direct

Name: frr [H]

Synonym: MPN636

Alternate gene names: 13508375

Gene position: 762639-763193 (Clockwise)

Preceding gene: 13508374

Following gene: 13508376

Centisome position: 93.42

GC content: 36.94

Gene sequence:

>555_bases
ATGAGTCCAGAAAAATACCTGAACTTCTTTAAAGAAACCGCTGATAAAAAGTTCCAATGACTCAAAGAAGAATTGAGCAA
AATCCGTACTGGTAGACCTAATCCAAAACTGTTTGATAATCTCCTTGTGGAAAGCTATGGTGACAGAATGCCAATGGTAG
CATTAGCACAAATTGCGGTAAATCCACCGCGGGAAATTGTGATCAAGCCGTTTGACGTTAAAAACAATATTAATGCCATC
TACAGCGAAATTCAACGTGCTAACTTAGGTGTACAACCAGTGATTGACGGAGATAAAATTCGCATTAACTTTCCCCCAAT
GACCCAAGAAAGTCGTTTGGAAAGCATTAAGCAAGCTAAAAAAGTAGTGGAACAAATCCACCAAGAGTTGCGCAGTGTGC
GACGTGATACCCTTCAAATGATTAAGAAGGATGATCATAAAGACGAAGACTTTGAAGAATTCTTAAAAGAAGAAGTAGAA
AAAGTTAACAAGCAGTATATTGCACAGTTAGAAACTATTCAAAAACAAAAAGAAAAAGAACTATTAGTGGTCTAA

Upstream 100 bases:

>100_bases
TTTAAACTAGGGCAAAGTAAATAATTAGTCCGTGTTTTACATTGTCGTTGAATTTCCGCAACCGCTTTCCATTAAAATAA
TTTAACGCCTGAATAAAGTG

Downstream 100 bases:

>100_bases
TGGATCTGAAAGATAATTCCTTCGCTAAAAAACGATCGACAGTGTTCGTTGTTTTGCTCATTGTCTTTTGTTTTTTTTTA
ATGTTTTCAGCCTTTGCTGA

Product: ribosome releasing factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSPEKYLNFFKETADKKFQWLKEELSKIRTGRPNPKLFDNLLVESYGDRMPMVALAQIAVNPPREIVIKPFDVKNNINAI
YSEIQRANLGVQPVIDGDKIRINFPPMTQESRLESIKQAKKVVEQIHQELRSVRRDTLQMIKKDDHKDEDFEEFLKEEVE
KVNKQYIAQLETIQKQKEKELLVV

Sequences:

>Translated_184_residues
MSPEKYLNFFKETADKKFQ*LKEELSKIRTGRPNPKLFDNLLVESYGDRMPMVALAQIAVNPPREIVIKPFDVKNNINAI
YSEIQRANLGVQPVIDGDKIRINFPPMTQESRLESIKQAKKVVEQIHQELRSVRRDTLQMIKKDDHKDEDFEEFLKEEVE
KVNKQYIAQLETIQKQKEKELLVV
>Mature_183_residues
SPEKYLNFFKETADKKFQ*LKEELSKIRTGRPNPKLFDNLLVESYGDRMPMVALAQIAVNPPREIVIKPFDVKNNINAIY
SEIQRANLGVQPVIDGDKIRINFPPMTQESRLESIKQAKKVVEQIHQELRSVRRDTLQMIKKDDHKDEDFEEFLKEEVEK
VNKQYIAQLETIQKQKEKELLVV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Escherichia coli, GI1786368, Length=165, Percent_Identity=34.5454545454545, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 21463; Mature: 21332

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPEKYLNFFKETADKKFQLKEELSKIRTGRPNPKLFDNLLVESYGDRMPMVALAQIAVN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCC
PPREIVIKPFDVKNNINAIYSEIQRANLGVQPVIDGDKIRINFPPMTQESRLESIKQAKK
CCHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
VVEQIHQELRSVRRDTLQMIKKDDHKDEDFEEFLKEEVEKVNKQYIAQLETIQKQKEKEL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LVV
CCC
>Mature Secondary Structure 
SPEKYLNFFKETADKKFQLKEELSKIRTGRPNPKLFDNLLVESYGDRMPMVALAQIAVN
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCC
PPREIVIKPFDVKNNINAIYSEIQRANLGVQPVIDGDKIRINFPPMTQESRLESIKQAKK
CCHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
VVEQIHQELRSVRRDTLQMIKKDDHKDEDFEEFLKEEVEKVNKQYIAQLETIQKQKEKEL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LVV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]