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The map label for this gene is cdsA [H]

Identifier: 13508376

GI number: 13508376

Start: 763193

End: 764380

Strand: Direct

Name: cdsA [H]

Synonym: MPN637

Alternate gene names: 13508376

Gene position: 763193-764380 (Clockwise)

Preceding gene: 13508375

Following gene: 13508377

Centisome position: 93.48

GC content: 36.45

Gene sequence:

>1188_bases
ATGGATCTGAAAGATAATTCCTTCGCTAAAAAACGATCGACAGTGTTCGTTGTTTTGCTCATTGTCTTTTGTTTTTTTTT
AATGTTTTCAGCCTTTGCTGACGGCTTTAACTTTTGATCGCCTTGGTCAACTGATTTCAATTCACGCGTAATTCACATTA
AAAGTGACGGTAATATAGAAACCACTAGTATTGTCAGCCATGAGTTGCATCCTGACTTTAAGGCAGTCCGTTTTGCTTTT
GGCTTAGTGATAGTTTTATTTATTAGCGTTATTGCCGTTTTAATGAATTGGGAGTTGTCTAACAGTATCTTTAAAAACTA
TGAAAAGCTCAACTTATCCTTATCACTACTTAGTGGAATTATGGTTTCAGGTGGGATGATTCCAACCTTTTTCGTAATCT
ATTTCCGTGAATGAAATGCGACCGTTAACTGAATTTGAACTGCCTCGTTTGCTGGCATGATTGTCTTTTTATGGGCAGTG
TACATGATTAGCACTTCCTTCATAAAGATCCGACCATCATTGCAAGTGATTTATAGCCTAGGTGCAGTGATCTGTTTCAT
CGCTTGCATAGGTACAATTTACTTTTCCGTAATTAGGGGATGGACTACCATTTTTCTCTTAATTGCTATTGGCGTTTGCA
CTGATACCTTTGCTTATCTGTTTGGTAAACGTTTTGGAAAAAATCCCCTCATTAAAATTTCTCCCTCAAAAACTTGGGAA
GGTGCTTTCTTTGGGGTTACTGGTACAGTTTTAACCATTTCTATTATTTGTGTTTTGTACTCGATCCCTAACTATGTAAG
ACAACCTAGCATAAAGGATGCAAGTAAGACAGCACTACAAACACCACAAAACTATGATGTGCATAACCTTATTACCAATG
TCTTTCTCATCTCCTTCATTTCCGGTGGTAGTACCTTTTACATCTACTGGTGAGTTAGCACATTAGCACTGATATTTACT
GCTTCCATTTTTGCCATAGGTGGTGATTTATTCTTTAGTTACATTAAAAGACTCACAAAAATTAAGGATTTTTCGAAGTT
ATTGGGTAAACACGGTGGTATCTTAGACCGGTTTGATTCCAGCTCTTTTTTAATTAGTTTTTTCTTTATTTACCACGTAA
TTGCGGGAATCTCTTCTAACCAAAGATTGCTTATGGAACCAAACACTTATTTCAGTGCTGTAAGTTAG

Upstream 100 bases:

>100_bases
AAGAATTCTTAAAAGAAGAAGTAGAAAAAGTTAACAAGCAGTATATTGCACAGTTAGAAACTATTCAAAAACAAAAAGAA
AAAGAACTATTAGTGGTCTA

Downstream 100 bases:

>100_bases
TTTTTAGAATTTAAAGGAAATGACTCCTAAATTAAAGCTTAACACTAACAGTAATTGAACTAAGAAAACCCTTGGCAGCT
TATTTGAACTCAAGAAGGGT

Product: CDP-diglyceride synthetase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MDLKDNSFAKKRSTVFVVLLIVFCFFLMFSAFADGFNFWSPWSTDFNSRVIHIKSDGNIETTSIVSHELHPDFKAVRFAF
GLVIVLFISVIAVLMNWELSNSIFKNYEKLNLSLSLLSGIMVSGGMIPTFFVIYFREWNATVNWIWTASFAGMIVFLWAV
YMISTSFIKIRPSLQVIYSLGAVICFIACIGTIYFSVIRGWTTIFLLIAIGVCTDTFAYLFGKRFGKNPLIKISPSKTWE
GAFFGVTGTVLTISIICVLYSIPNYVRQPSIKDASKTALQTPQNYDVHNLITNVFLISFISGGSTFYIYWWVSTLALIFT
ASIFAIGGDLFFSYIKRLTKIKDFSKLLGKHGGILDRFDSSSFLISFFFIYHVIAGISSNQRLLMEPNTYFSAVS

Sequences:

>Translated_395_residues
MDLKDNSFAKKRSTVFVVLLIVFCFFLMFSAFADGFNF*SPWSTDFNSRVIHIKSDGNIETTSIVSHELHPDFKAVRFAF
GLVIVLFISVIAVLMNWELSNSIFKNYEKLNLSLSLLSGIMVSGGMIPTFFVIYFRE*NATVN*I*TASFAGMIVFLWAV
YMISTSFIKIRPSLQVIYSLGAVICFIACIGTIYFSVIRGWTTIFLLIAIGVCTDTFAYLFGKRFGKNPLIKISPSKTWE
GAFFGVTGTVLTISIICVLYSIPNYVRQPSIKDASKTALQTPQNYDVHNLITNVFLISFISGGSTFYIYW*VSTLALIFT
ASIFAIGGDLFFSYIKRLTKIKDFSKLLGKHGGILDRFDSSSFLISFFFIYHVIAGISSNQRLLMEPNTYFSAVS
>Mature_395_residues
MDLKDNSFAKKRSTVFVVLLIVFCFFLMFSAFADGFNF*SPWSTDFNSRVIHIKSDGNIETTSIVSHELHPDFKAVRFAF
GLVIVLFISVIAVLMNWELSNSIFKNYEKLNLSLSLLSGIMVSGGMIPTFFVIYFRE*NATVN*I*TASFAGMIVFLWAV
YMISTSFIKIRPSLQVIYSLGAVICFIACIGTIYFSVIRGWTTIFLLIAIGVCTDTFAYLFGKRFGKNPLIKISPSKTWE
GAFFGVTGTVLTISIICVLYSIPNYVRQPSIKDASKTALQTPQNYDVHNLITNVFLISFISGGSTFYIYW*VSTLALIFT
ASIFAIGGDLFFSYIKRLTKIKDFSKLLGKHGGILDRFDSSSFLISFFFIYHVIAGISSNQRLLMEPNTYFSAVS

Specific function: Unknown

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Homo sapiens, GI22035624, Length=178, Percent_Identity=33.7078651685393, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI20143480, Length=174, Percent_Identity=34.4827586206897, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17539014, Length=185, Percent_Identity=33.5135135135135, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539016, Length=185, Percent_Identity=33.5135135135135, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319503, Length=186, Percent_Identity=31.1827956989247, Blast_Score=63, Evalue=9e-11,
Organism=Drosophila melanogaster, GI17864222, Length=177, Percent_Identity=37.2881355932203, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 43624; Mature: 43624

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKDNSFAKKRSTVFVVLLIVFCFFLMFSAFADGFNFSPWSTDFNSRVIHIKSDGNIET
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEH
TSIVSHELHPDFKAVRFAFGLVIVLFISVIAVLMNWELSNSIFKNYEKLNLSLSLLSGIM
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VSGGMIPTFFVIYFRENATVNITASFAGMIVFLWAVYMISTSFIKIRPSLQVIYSLGAVI
HCCCCHHHEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHH
CFIACIGTIYFSVIRGWTTIFLLIAIGVCTDTFAYLFGKRFGKNPLIKISPSKTWEGAFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEE
GVTGTVLTISIICVLYSIPNYVRQPSIKDASKTALQTPQNYDVHNLITNVFLISFISGGS
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
TFYIYWVSTLALIFTASIFAIGGDLFFSYIKRLTKIKDFSKLLGKHGGILDRFDSSSFLI
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
SFFFIYHVIAGISSNQRLLMEPNTYFSAVS
HHHHHHHHHHCCCCCCEEEECCCHHHCCCC
>Mature Secondary Structure
MDLKDNSFAKKRSTVFVVLLIVFCFFLMFSAFADGFNFSPWSTDFNSRVIHIKSDGNIET
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCEEH
TSIVSHELHPDFKAVRFAFGLVIVLFISVIAVLMNWELSNSIFKNYEKLNLSLSLLSGIM
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VSGGMIPTFFVIYFRENATVNITASFAGMIVFLWAVYMISTSFIKIRPSLQVIYSLGAVI
HCCCCHHHEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHH
CFIACIGTIYFSVIRGWTTIFLLIAIGVCTDTFAYLFGKRFGKNPLIKISPSKTWEGAFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEE
GVTGTVLTISIICVLYSIPNYVRQPSIKDASKTALQTPQNYDVHNLITNVFLISFISGGS
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
TFYIYWVSTLALIFTASIFAIGGDLFFSYIKRLTKIKDFSKLLGKHGGILDRFDSSSFLI
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
SFFFIYHVIAGISSNQRLLMEPNTYFSAVS
HHHHHHHHHHCCCCCCEEEECCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]