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The map label for this gene is hsdR

Identifier: 13508084

GI number: 13508084

Start: 412681

End: 413301

Strand: Direct

Name: hsdR

Synonym: MPN345

Alternate gene names: NA

Gene position: 412681-413301 (Clockwise)

Preceding gene: 13508083

Following gene: 13508085

Centisome position: 50.55

GC content: 32.69

Gene sequence:

>621_bases
ATGAGATGAAGTGACTCTGAAAACAATAAAATCGACTATATTGAAGACTTTGCAACTCATTTTTTAAACAAAAACGCCTT
ATTAAACGTTATTTGTAAATTTTGTGTGTTCAGGTCAAATAGTGATCTTTGAGTTATGCGTCCTTACCAAATATGCGCAA
CTGAAAGAATTTTAGAAAAAATAAAAGAAGACAATAGGAACAGTAAAAACTCTAAAAATGCAAGTAAGGGCGGCTGTATT
TGACACTCAACCGGAAGTGGTAAAACACTAACTTCTTTTAAAGCTGTTCAATTGGCTAGTGAAATAGACTTTGTTGATAA
AGTCCTTTTCGTTGTTGACAGGAAAGACTTGGACAACCAAACGATCGAAGAATATGAAAAGTTTCAAGCGGGTTCTGTTA
GCGAAACTGAGAACACAAATGATCTTAAAGAAAAGATATTAGACGATAGTACCGCCACACGTGCAATTGTTACTACTATT
CATAAACTTAAGAGGTTAATAGATCAGAGAAGTAAGCTTAAAGACGAAGATCTTAAAAAGAAAAACATCGTTCTTATATT
CGATGAATGTCATCGATCTCAATTTGGAAAAATGAAACAAGAAATCGATGAGTTTTTTTAA

Upstream 100 bases:

>100_bases
CGCAAAGGAAACAAGATACTGCTCAATAACAACATGGGATAACCTTAAAGAAAAAAGGAAATCAGTAAGAGGATTGTCAA
ACTCTTCTTTTAAAAGTTTG

Downstream 100 bases:

>100_bases
AATGGGATTTTATTTGGCTTTACTGGAACGCCTATTTTTGAAAGTGAATATTCAGACAAGAATCAAACTCTAGAGAACCA
GCAAAAGACAACTAGAAGTA

Product: type I restriction enzyme

Products: NA

Alternate protein names: MpnORFDBP; Putative type I restriction enzyme MpnORFDP R protein part 2 [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MRWSDSENNKIDYIEDFATHFLNKNALLNVICKFCVFRSNSDLWVMRPYQICATERILEKIKEDNRNSKNSKNASKGGCI
WHSTGSGKTLTSFKAVQLASEIDFVDKVLFVVDRKDLDNQTIEEYEKFQAGSVSETENTNDLKEKILDDSTATRAIVTTI
HKLKRLIDQRSKLKDEDLKKKNIVLIFDECHRSQFGKMKQEIDEFF

Sequences:

>Translated_206_residues
MR*SDSENNKIDYIEDFATHFLNKNALLNVICKFCVFRSNSDL*VMRPYQICATERILEKIKEDNRNSKNSKNASKGGCI
*HSTGSGKTLTSFKAVQLASEIDFVDKVLFVVDRKDLDNQTIEEYEKFQAGSVSETENTNDLKEKILDDSTATRAIVTTI
HKLKRLIDQRSKLKDEDLKKKNIVLIFDECHRSQFGKMKQEIDEFF
>Mature_206_residues
MR*SDSENNKIDYIEDFATHFLNKNALLNVICKFCVFRSNSDL*VMRPYQICATERILEKIKEDNRNSKNSKNASKGGCI
*HSTGSGKTLTSFKAVQLASEIDFVDKVLFVVDRKDLDNQTIEEYEKFQAGSVSETENTNDLKEKILDDSTATRAIVTTI
HKLKRLIDQRSKLKDEDLKKKNIVLIFDECHRSQFGKMKQEIDEFF

Specific function: Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG0610

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR006935 [H]

Pfam domain/function: PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 23345; Mature: 23345

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSDSENNKIDYIEDFATHFLNKNALLNVICKFCVFRSNSDLVMRPYQICATERILEKIK
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHH
EDNRNSKNSKNASKGGCIHSTGSGKTLTSFKAVQLASEIDFVDKVLFVVDRKDLDNQTIE
HHCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
EYEKFQAGSVSETENTNDLKEKILDDSTATRAIVTTIHKLKRLIDQRSKLKDEDLKKKNI
HHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCE
VLIFDECHRSQFGKMKQEIDEFF
EEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRSDSENNKIDYIEDFATHFLNKNALLNVICKFCVFRSNSDLVMRPYQICATERILEKIK
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHH
EDNRNSKNSKNASKGGCIHSTGSGKTLTSFKAVQLASEIDFVDKVLFVVDRKDLDNQTIE
HHCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
EYEKFQAGSVSETENTNDLKEKILDDSTATRAIVTTIHKLKRLIDQRSKLKDEDLKKKNI
HHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCE
VLIFDECHRSQFGKMKQEIDEFF
EEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]