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The map label for this gene is cfxE

Identifier: 13507990

GI number: 13507990

Start: 302383

End: 303030

Strand: Direct

Name: cfxE

Synonym: MPN251

Alternate gene names: 13507990

Gene position: 302383-303030 (Clockwise)

Preceding gene: 13507989

Following gene: 13507991

Centisome position: 37.04

GC content: 40.9

Gene sequence:

>648_bases
TTGCTAAACTTGGTCGTGAATAGGGAAATTGCCTTTTCGCTTTTACCACTGTTACACCAGTTTGACCGCAAGTTGTTAGA
ACAATTCTTTGCGGACGGCTTGCGCTTAATCCACTATGACGTGATGGACCATTTTGTGGACAACACTGTCTTTCAAGGGG
AACATTTAGATGAATTACAACAAATTGGTTTTCAGGTCAATGTACATTTGATGGTACAAGCATTAGAACAAATCTTGCCA
GTATACCTCCACCATCAAGCCGTTAAGCGCATTTCCTTTCACGTTGAACCGTTTGATATCCCTACCATCAAACACTTTAT
TGCGCAAATTAAACAAGCGGGAAAACAAGTCGGTTTAGCGTTTAAATTCACCACTCCGCTTGTAAATTACGAGCGCTTGG
TGCAACAACTGGACTTTGTTACCTTAATGAGTGTCCCCCCAGGAAAGGGCGGGCAAGCCTTTAACAGTGCTGTTTTTAAT
AACTTAAAACAAGCCCACAAATACCACTGCTCAATTGAAATCGATGGTGGGATCAAATTAGATAACATTCACCAAATCCA
GGATGATGTCAATTTTATTGTCATGGGAAGTGGCTTTATAAAATTAGAACGATGGCAGCGCCAACAGCTGCTCAAAACCA
ATCAATAA

Upstream 100 bases:

>100_bases
TTTTACTTCTGGTTATCAATGGCCACAATGATGAGTGGTTCACTGCTGGGACACAACGTCTTTGATCAACCAGGGGTGGA
AGTGTACAAGCAGTTAATGT

Downstream 100 bases:

>100_bases
CTTTATATGTCTGCAACTGCTATTAGCGATCTCTTTGAAAAACCAGCCCAATTTAAAAACAAGAAAATTAAGCTAACGGG
TTGATTGAAAAACAAACGTA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MLNLVVNREIAFSLLPLLHQFDRKLLEQFFADGLRLIHYDVMDHFVDNTVFQGEHLDELQQIGFQVNVHLMVQALEQILP
VYLHHQAVKRISFHVEPFDIPTIKHFIAQIKQAGKQVGLAFKFTTPLVNYERLVQQLDFVTLMSVPPGKGGQAFNSAVFN
NLKQAHKYHCSIEIDGGIKLDNIHQIQDDVNFIVMGSGFIKLERWQRQQLLKTNQ

Sequences:

>Translated_215_residues
MLNLVVNREIAFSLLPLLHQFDRKLLEQFFADGLRLIHYDVMDHFVDNTVFQGEHLDELQQIGFQVNVHLMVQALEQILP
VYLHHQAVKRISFHVEPFDIPTIKHFIAQIKQAGKQVGLAFKFTTPLVNYERLVQQLDFVTLMSVPPGKGGQAFNSAVFN
NLKQAHKYHCSIEIDGGIKLDNIHQIQDDVNFIVMGSGFIKLERWQRQQLLKTNQ
>Mature_215_residues
MLNLVVNREIAFSLLPLLHQFDRKLLEQFFADGLRLIHYDVMDHFVDNTVFQGEHLDELQQIGFQVNVHLMVQALEQILP
VYLHHQAVKRISFHVEPFDIPTIKHFIAQIKQAGKQVGLAFKFTTPLVNYERLVQQLDFVTLMSVPPGKGGQAFNSAVFN
NLKQAHKYHCSIEIDGGIKLDNIHQIQDDVNFIVMGSGFIKLERWQRQQLLKTNQ

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family

Homologues:

Organism=Homo sapiens, GI40385883, Length=184, Percent_Identity=30.9782608695652, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI219879828, Length=183, Percent_Identity=30.0546448087432, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI1789788, Length=190, Percent_Identity=30.5263157894737, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17552948, Length=184, Percent_Identity=31.5217391304348, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24586301, Length=182, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPE_MYCPN (P75522)

Other databases:

- EMBL:   U00089
- PIR:   S73907
- RefSeq:   NP_109939.1
- ProteinModelPortal:   P75522
- GeneID:   876912
- GenomeReviews:   U00089_GR
- KEGG:   mpn:MPN251
- HOGENOM:   HBG571751
- OMA:   MYRIAPS
- ProtClustDB:   PRK05581
- BioCyc:   MetaCyc:MONOMER-582
- BioCyc:   MPNE272634:MPN251-MONOMER
- BRENDA:   5.1.3.1
- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR11749

Pfam domain/function: PF00834 Ribul_P_3_epim; SSF51366 RibP_bind_barrel

EC number: =5.1.3.1

Molecular weight: Translated: 24853; Mature: 24853

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNLVVNREIAFSLLPLLHQFDRKLLEQFFADGLRLIHYDVMDHFVDNTVFQGEHLDELQ
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHH
QIGFQVNVHLMVQALEQILPVYLHHQAVKRISFHVEPFDIPTIKHFIAQIKQAGKQVGLA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCEE
FKFTTPLVNYERLVQQLDFVTLMSVPPGKGGQAFNSAVFNNLKQAHKYHCSIEIDGGIKL
EEECCCCCCHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCEEE
DNIHQIQDDVNFIVMGSGFIKLERWQRQQLLKTNQ
CHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNLVVNREIAFSLLPLLHQFDRKLLEQFFADGLRLIHYDVMDHFVDNTVFQGEHLDELQ
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHH
QIGFQVNVHLMVQALEQILPVYLHHQAVKRISFHVEPFDIPTIKHFIAQIKQAGKQVGLA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCEE
FKFTTPLVNYERLVQQLDFVTLMSVPPGKGGQAFNSAVFNNLKQAHKYHCSIEIDGGIKL
EEECCCCCCHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCEEE
DNIHQIQDDVNFIVMGSGFIKLERWQRQQLLKTNQ
CHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8948633